748 research outputs found
Arun Shourie and his Christian critic
No full textCritique by Fr. Augustine Kanjamala on Arun Shourie's Missionaries in India and response to it by the author
Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature
No full textThe epidemiology of microbial keratitis has been investigated in several studies by analysis of organisms cultured from corneal scrapes. However, a comparison of the frequency of different organisms causing keratitis in different parts of the world is lacking. The authors present a review incorporating an analysis of data from studies worldwide. The data provide a comparison of the frequency of culture-positive organisms found in different parts of the world. Associations between a country's gross national income and types of causative organism are explored. The highest proportion of bacterial corneal ulcers was reported in studies from North America, Australia, The Netherlands and Singapore. The highest proportion of staphylococcal ulcers was found in a study from Paraguay, while the highest proportion of pseudomonas ulcers was reported in a study from Bangkok. The highest proportions of fungal infections were found in studies from India and Nepal. The Spearman correlation coefficient demonstrated statistically significant correlations between gross national income and percentages of bacterial (0.85 (95% CI 0.68 to 0.91, p<0.0001)), fungal (–0.81 (95% CI ?0.90 to ?0.66, p<0.0001)) and streptococcal (?0.43 (95% CI ?0.66 to ?0.12, p=0.009)) isolates
R16. Formulation and Evaluation of Doxorubicin HCl Nanoliposomes by Ethanol Injection Method
No full textCorresponding author (Pharmaceutics and Drug delivery): Arun Kumar Kotha, [email protected]://egrove.olemiss.edu/pharm_annual_posters/1015/thumbnail.jp
Extracellular vesicles from mouse trophoblast cells: effects on neural progenitor cells and potential participants in the placenta-brain Axis
No full textThe fetal brain of the mouse is thought to be dependent upon the placenta as a source of serotonin (5-hydroxytryptamine; 5-HT) and other factors. How factors reach the developing brain remains uncertain but are postulated here to be part of the cargo carried by placental extracellular vesicles (EV). We have analyzed the protein, catecholamine, and small RNA content of EV from mouse trophoblast stem cells (TSC) and TSC differentiated into parietal trophoblast giant cells (pTGC), potential primary purveyors of 5-HT. We have examined how exposure of mouse neural progenitor cells (NPC) to EV from either TSC or pTGC affect their transcriptome profiles. The EV from TB cells contained relatively high amounts of 5-HT, as well as dopamine and norepinephrine, but there were no significant differences between EV derived from pTGC and from TSC. Content of miRNA and small nucleolar (sno)RNA, however, did differ according to EV source, and snoRNA were upregulated in EV from pTGC. The primary inferred targets of the miRNA from both pTGC and TSC were mRNA enriched in the fetal brain. NPC readily internalized EV, leading to changes in their transcriptome profiles. Transcripts regulated were mainly ones enriched in neural tissues. The transcripts in EV-treated NPC that demonstrated a likely complementarity with miRNA in EV were mainly up- rather than down-regulated, with functions linked to neuronal processes. Our results are consistent with placenta-derived EV providing direct support for fetal brain development and being an integral part of the placenta-brain axis.This is a manuscript of an article published as Jessica A Kinkade, Arun S Seetharam, Shrikesh Sachdev, Nathan J Bivens, Brett S Phinney, Gabriela Grigorean, R Michael Roberts, Geetu Tuteja, Cheryl S Rosenfeld, Extracellular vesicles from mouse trophoblast cells: effects on neural progenitor cells and potential participants in the placenta-brain Axis, Biology of Reproduction, 2023;, ioad146, https://doi.org/10.1093/biolre/ioad146. © The Author(s) 2023. Posted with permission
Understanding the value-chain of counterfeit products: A multimethod investigation
No full textThe student, - Sreekumar Arun, accepted the attached license on 2021-04-13 at 23:09.The student, - Sreekumar Arun, submitted this Dissertation for approval on 2021-04-13 at 23:23.This Dissertation was approved for publication on 2021-04-15 at 11:53.DSpace SAF Submission Ingestion Package generated from Vireo submission #16317 on 2021-09-16 at 17:03:02Made available in DSpace on 2021-09-17T02:34:25Z (GMT). No. of bitstreams: 2
SREEKUMARARUN-DISSERTATION-2021.pdf: 1165555 bytes, checksum: 5224c2afec936d334243407f8cdc4a58 (MD5)
LICENSE.txt: 4213 bytes, checksum: 6a931b7df048f222f1bf46543b830705 (MD5)
Previous issue date: 2021-04-15Embargo set by: Seth Robbins for item 118507
Lift date: 2023-09-17T02:34:57Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I OnlyThe context of this dissertation is the market for counterfeit products, which accounts for more than one trillion US dollars of trade globally every year. Entrepreneurs who manufacture and market these products are clandestine and operate in the black market. Drawing from this context, this dissertation seeks to advance knowledge on how entrepreneurs strategically use ambiguity in marketing communications, and in relationships with other firms. The first essay examines how and why equivocation is used as a persuasive strategy by sellers of counterfeit products. This essay develops a framework that can help qualitatively and quantitatively identify equivocation rhetoric in firm-generated text. The second essay examines how relationships between firms are managed when one of the firms employs ambiguity as a protection strategy. Specifically, the essay sheds light on how manufacturers and retailers of counterfeit products succeed in maintaining ambiguity, and in managing relationship tension arising from ambiguity. Put together, the essays present an investigation of how counterfeit manufacturers and retailers conduct their marketing functions despite being clandestine and illegal.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-05-0
Author Correction: A shared neural basis underlying psychiatric comorbidity
No full textCorrection to: Nature Medicine. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Hervé Lemaître, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivières. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Hervé Lemaître, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivières and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivières. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article
Improvement in Central Serous Chorioretinopathy Following Multiwavelength Photobiomodulation Treatment – Case Report
No full textAbstract Introduction Central serous chorioretinopathy (CSCR) is a condition where fluid build-up accumulates underneath the retina, resulting in retinal pigment epithelium (RPE) detachment and vision loss. Irreversible retinal functional and anatomical changes are possible consequences. Research into novel strategies to aid in recovery are of interest. Photobiomodulation (PBM) uses light wavelengths to improve cellular function and shows positive effects in several conditions including those with edema. Methods This prospective case report details a 39-year-old woman with CSCR. Multiwavelength PBM treatment was initiated with the Valeda® Light Delivery System. A series of treatment included nine sessions delivered over 3–5 weeks. Follow-up treatments were conducted. Optical coherence tomography (OCT) imaging and best-corrected visual acuity (BCVA) measures were taken. The patient has been followed for approximately 1 year. Results The patient presented with blurred vision and a BCVA score of 65 letters in the left eye. After 3 weeks of observation, the patient’s vision had further declined two lines on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart to 55 letters. Fluorescein angiography was performed, confirming CSCR diagnosis, and PBM was initiated. PBM treatment improved BCVA and fluid build-up in the RPE within 1 week of treatment (three treatment sessions). Following the full series of treatment (nine PBM treatment sessions), fluid was completely resolved and BCVA scored at 80 letters. The patient had a repeat PBM treatment series ~ 6 months later and has shown stable vision and no fluid present on OCT scan. The patient was seen again ~ 1 year later with continued stable vision and no fluid detection. Conclusions PBM is a non-invasive treatment option that may provide benefit in CSCR to resolve fluid build-up, macular change, and vision loss. Research into PBM as an immediate treatment option for CSCR, especially those with chronic presentations or those posed to have irreversible damage, is warranted to confirm effectiveness
Seismic Velocities of the Whitestone Anorthosite and its Mylonitized Equivalents in the Parry Sound Shear Zone
No full textTitle: Seismic Velocities of the Whitestone Anorthosite and its Mylonitized Equivalents in the Parry Sound Shear Zone, Author: Arun Sen, Location: ThodeCompressional wave velocities of the Whitestone anorthosite and its mylonitic equivalent in the Parry Sound shear zone have been measured in the field and to two kilobars in a laboratory confining pressure vessel. Mylonitiztion of the anorthosite has resulted in a preferred orientation of constituent minerals and retrograde mineral assemblages. A seimic anisotropy is consequently developed in the mylonite such that the P-wave velocitites are lower for propagation directions perpendicular to mylonite than for its anorthosite protolith. In the field, rock weathering and surface fractures control velocity variations. At low confining pressure (shallow depth) the P-wave velocity anisotropy is controlled by fracturing which is in turn related to the mylonitic fabric. At approximately one kilobar pressure (depths close to five kilometres) where fractures and porosity are insignificant, the P-wave anisotropy is due solely to the aggregate mineral velocities and their solution and their orientations. The undeformed Whitestone anorthosite has an average P-wave velocity of 7.02 km/s measured in three perpendicular directions at 2 kilobars confining pressure. The mylonite has the following P-wave velocities at 2 kilobars confining pressure: 6.83 km/s parallel to both foliation and lineation, 6.70 km/s parallel to foliation and perpendicular to lineation, and 6.57 km/s perpendicular to foliation.ThesisBachelor of Science (BSc
- …
