122,661 research outputs found
Ophthalmic complications of spina bifida and hydrocephalus
No full textThis thesis represents an attempt to further our knowledge of the ophthalmic complications of spina bifida and hydrocephalus by means of literature review and a long term clinical study, and to determine whether regular ophthalmic supervision can assist in the general management of affected children. The ophthalmic complications of spina bifida have often been reported in the literature and thought to merit regular supervision of affected children, yet few centres currently offer this service. In this study 322 children attending one regional centre were examined repeatedly over a six year period by one ophthalmologist. Ophthalmic complications were found to be very common. They frequently provided evidence of raised intracranial pressure due to shunt dysfunction even when other objective evidence was lacking. Every spina bifida and hydrocephalus clinic should have an ophthalmalogist in its medical team. Preservation of visual function and early diagnosis of raised intracranial pressure in these children should result from this arrangement
Plasma antidiuretic hormone levels in children with spina bifida
No full textPURPOSE:
Urological management of spina bifida patients is controversial. The goals of therapy of neurogenic bladder are continence, prevention of infections and preservation of urinary tract. Desmopressin has been recently used in a spina bifida population that is dry during the day (daytime continence was achieved with clean intermittent catheterization and anticholinergics) but wet at night. The aim of this study was to assess plasma antidiuretic hormone (ADH) levels in these children.
MATERIALS AND METHODS:
The study included 24 patients, 11 males and 13 females (mean age 6.4 years) referred to the Spina Bifida Centre of the Catholic University of Rome, and 57 normal age-matched controls. Morning (07.30-08.00 h) plasma ADH levels were measured using a specific radioimmunoassay.
RESULTS:
Plasma ADH levels (normal range 5-11 microg/l) did not differ between spina bifida population and healthy controls. Serum ADH had a mean of 6.8 microg/l in affected children and a mean of 7.4 microg/l in the controls.
CONCLUSION:
We conclude that the use of desmopressin in children with spina bifida should be reserved only in patients with decreased secretion of ADH, or may be useful in patients with persistent nocturnal incontinence to reduce night wetting. Therefore, research with a larger population is needed
Spina Bifida, Obesity, and Health: A Case Study
No full textABSTRACT\ud
SPINA BIFIDA, OBESITY, AND HEALTH: A CASE STUDY\ud
by\ud
Kerri A. McMurtry\ud
Master of Arts in Kinesiology\ud
California State University, Chico\ud
Spring 2010\ud
This investigation described the physiological characteristics of two trained subjects with spina bifida\(TSB). The subjects were of normal weight and met the ACSM guidelines for participating in physical exercise. The data were compared with existing data untrained subjects with spina bifida (UTSB).\ud
Peak power output (POpeak) and peak oxygen uptake (VO2peak) were assessed using arm ergometry. Body composition was assessed using dual x-ray absorptiometry. Glucose tolerance was determined using an oral glucose tolerance test (OGTT) after an overnight fast.\ud
VO2peak was 33% greater in male TSB compared to UTSB and female TSB VO2peak was 43% higher compared to UTSB. POpeak was 70 watts in the male TSB compared to 62 watts in the UTSB, a difference of 12%. Female TSB POpeak was 19% greater than UTSB (60 vs. 48.9 watts). Body fat percentage was 26.6% and 36% in male TSB and UTSB, respectively. Body fat percentage was 29 and 46% in female TSB and\ud
x\ud
UTSB. Fasting blood glucose in TSB was 89.5 mg/dl which is comparable to UTSB. After consuming a 75 gram glucose load, blood glucose was 127, 124, 111, and 62 mg/dl at 30, 60, 90, and 120 min in TSB.\ud
The results of the present study must be interpreted with caution it was a case study of two individuals. However, we can infer from these data that people who are physically active and within a normal weight respond positively to exercising as indicated by the higher VO2peak and maximum power output and more robust body composition (i.e., lower percent fat and high fat-free weight. This study supported the role of physical activity in promoting health in people with spina bifida.CSU, Chic
L^p estimates for the Caffarelli-Silvestre extension operators
No full textWe study elliptic and parabolic problems governed by the singular elliptic operators L= x+Dyy+ c yDy − b y2 in the half-space RN+1 + ={(x, y) :x∈RN, y>0}
Abnormal skull findings in neural tube defects
No full textThe human neural tube develops and closes during the third and fourth week after conception and is normally completed by 28 days post-conception. Malformations, knows as neural tube defects, occure, when the normal closure process fails. Several clinical types of neural tube defects are recognized, anencefaly and spina bifida being the most common. Such malformations are generally associated with cranial abnormlities
Asymptotic behaviour for elliptic operators with second-order discontinuous coefficients
No full textWe study the behaviour at infinity, in suitable weighted Lp -norms, of solutions of parabolic problems associated to the second order elliptic operator L = Δ + (a - 1) σi, j = 1N x i x j /| x | 2 Di j + c x /| x |2 · - b| x |- 2, where a > 0 and b, c ε &Rdbll
Voci di esperienze vissute
No full textQuali sono le motivazioni profonde che spingono un marito, un amante, un compagno, una fidanzata a trasformarsi in stalker? E perché la vittima alle prime avvisaglie di aggressività non allontana da sé la persona che la minaccia ma gli resta accanto negando l’evidenza dei fatti? Cosa si fa per incoraggiare la vittima a rompere il silenzio e a denunciare l’abuso? Partendo da questi cruciali interrogativi il testo intende contribuire all’individuazione e analisi dei fattori che principalmente motivano la violenza, focalizzando la relazione triadica molestia–vittima–paura, il quadro di personalità e gli aspetti comportamentali di ciascun membro della coppia stalker–vittima che caratterizzano il fenomeno stalking. In particolare, la disamina della normativa in previsione del delitto di “Atti persecutori” integra e definisce più precisamente i reali bisogni della vittima e l’atteggiamento ossessivo dello stalker, affrontando la fattispecie di reato prevista dall’art. 612-bis c.p., e, segnatamente, le esigenze di tutela sociale che hanno portato alla sua introduzione, la struttura del reato attraverso un’analisi dell’autore di condotte criminose e degli eventi necessari per la integrazione del delitto, la giurisprudenza in materia, le misure adottabili contro l’autore del reato e le misure a sostegno delle vittime, con evidenziazione delle relative criticità
Spina bifida : review
No full textSpina bifida is a birth defect of the neural tube that results in an incomplete closure of the spinal column. There are four distinct forms of spina bifida, and depending upon the form, there is an extensive range in the severity of the spinal injury, as well as the secondary conditions that often accompany spina bifida. Treatments for the disorder range from intensive surgical methods to the simple use of medications to treat secondary complications. Although contingent upon the severity of the physical and cognitive dysfunction, those suffering from spina bifida experience similar, though delayed, independence and growth from adolescence to adulthood. Though a vast amount of knowledge has been gained in recent decades, much knowledge is still needed in order to fully understand the molecular and genetic pathways, which lead to the development of spina bifida, and as this knowledge is gained, better treatment methods will result.Thesis (B.?.)Honors Colleg
L^p estimates for Baouendi-Grushin operators
No full textWe prove Lp estimates for the Baouendi–Grushin operator ∆x + |x|α ∆y in Lp (RN+M), 1 < p < ∞, where x ∈ RN, y ∈ RM. When p = 2 more general weights belonging to the reverse Hölder class B2 (RN) are allowed
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