1,721,079 research outputs found
Occurrence of Incisional Complications After Closure of Equine Ventral Midline Celiotomies With 2 Polyglycolic Acid in Simple Interrupted Suture Pattern
No full textThe aim of this retrospective study was to describe the use of simple interrupted suture pattern for the closure of the abdomen after ventral midline celiotomy in horses and to evaluate the prevalence of resulting incisional complications. Seventy horses undergoing abdominal surgery (2006–2015) and surviving at least 30 days were included in the study. Closure technique of the abdominal wall was performed on three layers. Linea alba was closed with a simple interrupted pattern using number two coated braided absorbable polyglycolic acid suture. Follow-up information was recovered at the 90th day postoperatively. Incisional complications considered included drainage, infection, dehiscence, and herniation. The complications observed in the present study using simple interrupted suture pattern were 4.29% (3 of 70), lower than reported in literature with different suture pattern. Simple interrupted suture pattern could be a valid option for the closure of linea alba after ventral midline celiotomy in horses
Le basi patogenetiche delle malattie chirurgiche nei piccoli animali. Prima edizione italiana
No full textM.J.BOJRA
Short-term General Anesthesia With Tiletamine/Zolazepam in Horses Sedated With Medetomidine for Castration Under Field Conditions
No full textThe objective of the study is to evaluate the anesthetic effect produced by the tiletamine/zolazepamassociation in horses sedated with medetomidine undergoing orchiectomy underfield conditions. Tenuncastrated male horses, American Society of Anesthesiologists category I, undergoing orchiectomy,were enrolled in the study. The horses received acepromazine (0.03 mg kg1intramuscularly) 30 mi-nutes before sedation with medetomidine (8mgkg1intravenously). Anesthesia was induced withtiletamine/zolazepam (0.7 mg kg1intravenously). During anesthesia, heart rate (HR), pulse quality,respiratory rate, temperature, SpO2, movement, and reflexes were measured every 5 minutes. Arterialblood gases were evaluated before the premedication and during the surgical procedure. The quality ofinduction and recovery was recorded. The sedation was appropriate, and the quality of recovery wasevaluated as good. A statistically significant difference was revealed between the basal and intra-anesthesia HR. No differences were observed in blood gas parameters during the procedure. The re-sults suggested that general anesthesia produced with tiletamine/zolazepam for induction in horsessedated with medetomidine is suitable during orchiectomy underfield conditions
The influence of environmental variables on platelet concentration in horse platelet-rich plasma
Full text linkPlatelet-rich plasma (PRP) commonly refers to blood products which contain a higher platelet (PLT) concentration as compared to normal plasma. Autologous PRP has been shown to be safe and effective in promoting the natural processes of soft tissue healing or reconstruction in humans and horses. Variability in PLT concentration has been observed in practice between PRP preparations from different patients or from the same individual under different conditions. A change in PLT concentration could modify PRP efficacy in routine applications. The aim of this study was to test the influence of environmental, individual and agonistic variables on the PLT concentration of PRP in horses. Six healthy Standardbred mares were exposed to six different variables with a one-week washout period between variables, and PRP was subsequently obtained from each horse. The variables were time of withdrawal during the day (morning/evening), hydration status (overhydration/dehydration) treatment with anti-inflammatory drugs and training periods on a treadmill. The platelet concentration was significantly higher in horses treated with a non-steroidal anti-inflammatory drug (P= 0.03). The leukocyte concentration increased 2-9 fold with respect to whole blood in the PRP which was obtained after exposure to all the variable considered. Environmental variation in platelet concentration should be taken into consideration during PRP preparation
Clinical Evaluation of Intralesional Injection of Platelet-Rich Plasma for the Treatment of Proximal Suspensory Ligament Desmitis in Horses
No full textThe study clinically evaluated the effectiveness of autologous platelet-rich plasma (PRP), obtained using a double transfusion bag after an ultrasound-guided intralesion injection into an acute lesion of proximal portion of suspensory ligament (SL). Twenty horses with acute proximal suspensory ligament desmitis were included in the study. An ultrasound evaluation of the proximal region of the SL was carried out, and the cross-sectional area (CSA) percentage and fiber score alignment were determined. Four hundred fifty milliliters of blood was collected, and PRP was obtained by means of the buffy coat method, using a double transfusion bag. The PRP was injected into the lesion using an ultrasound guide. A long-term follow-up was carried out by means of a telephonic interview with the owner. The median CSA of the SL lesion at the first examination was 30%. The median platelet count in the PRP was 1,045 × 103 platelets/μL; the final concentration ranged from six to 20 times higher than the platelet blood count. Sixteen horses returned to activity within a period ranging from 12 to 24weeks from the last PRP injection, and four animals recidivated in different regions of suspensory ligament: midbody desmitis and medial branch. Clinical results confirm that the use of autologous PRP supports healing and reduces recurrence in acute SL lesions
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Evaluation of Protein Carbonyl Content in Healthy and Sick Hospitalized Horses
Full text linkLiterature on the protein carbonyl content (PCC) evaluation in horses is scarce, thus the aims were to evaluate the PCC in healthy and SIRS (Systemic Inflammatory Response Syndrome) horses and to investigate the performances of PCC in terms of sensitivity, specificity, and likelihood ratio in identifying SIRS positive and negative horses. A total of 72 adult horses were included. All the horses underwent to a complete physical examination, blood analysis, and were evaluated for the SIRS status. Blood samples were collected once in healthy horses and at admission time, then 24, 48, 72, and 96 h after admission in sick animals. PCC was evaluated using amethod previously described. Data were statistically analyzed to verify differences in PCC between healthy vs. SIRS positive or SIRS negative horses at all sampling time. The receiver operating characteristic (ROC) curve was performed to verify sensitivity and specificity of PCC in the diagnosis of SIRS-positive and SIRS negative horses. The healthy horses were standardbred mares with a median age of 8.5 years. The sick horses were 31/54 females, 16/54 geldings, and 7/54 stallions of different breeds and with a median age of 12 years old. Eight out of 54 sick horses were SIRS negative, while 46/54 were SIRS positive. Statistically significant differences were obtained between healthy and SIRS positive horses, while no differences were observed between healthy and SIRS negative horses at any sampling time. The best cutoff value of PCC to discriminate between SIRS positive, SIRS negative, and healthy horses, the sensitivity and specificity of cutoff point, the area under receiver operating characteristic curve, the 95%confidence intervals, and the likelihood ratio were reported. We found higher PCC values in sick SIRS-positive horses vs. healthy ones with a decrement over time, while no differences at admission, nor during the observational period, were obtained in sick but SIRS-negative horses. The value of 0.049 nmol/ml/mg is reported as a potential cutoff for the diagnosis of SIRS positivity vs. healthy horses with a sensibility of 74.5% and a specificity of 72.2%. In conclusion, PCC seems to be a sensitive and specific marker for SIRS in horses
High pressure gas distention in equine arthroscopy. 425 cases
No full textThe aim of this study is to underline the suitability of high pressure (250-300 mmHg) joint distension by use of CO2 for arthroscopic procedures and to evaluate and identify technical advantages and disadvantages that might be associated with this technique in horses. The choice of the medium used to obtain joint distension has been critically reviewed and for each distension medium advantages and disadvantages have been detected. Fluids and gases can be used to the purpose and currently Ringer’s sterile solution is mostly used. Main advantages in using gases vs fluids as distension media have been described more in human than in veterinary medicine literature. They are due to 3 major physical principles: better dioptric effect, evenly distributed wall pressure, and gravity without floating effect. In all of the papers describing gas arthroscopy techniques it is suggested not to increase the gas pressure above a threshold of 100-150 mmHg depending on the experiences of the authors to minimize the risk of both venous gas embolism and subcutaneous emphysema
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