186,972 research outputs found

    Il paradigma interrogante dei Minori Stranieri Non Accompagnati. Sfide, questioni e pratiche educative

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    Giovani, stranieri, soli e in un Paese che non è il loro. Proviamo a guardarli così, come ai ragazzi che sono, adolescenti spaventati e dalle molte speranze, fiaccati dalle fatiche di un viaggio che li segnerà per sempre, ma pieni di energie per i sogni che li hanno fatti partire. La questione ci riguarda, riguarda noi. Questi minori ci interroghino e mettono a nudo (e in discussione), in modo per certi versi paradigmatico, la nostra idea di alterità culturale, non tanto in senso astratto, ma in quanto calata nella pratiche concrete di accoglienza e integrazione. Il contributo delinea le principali sfide pedagogiche e questioni educative legate al lavoro con i minori stranieri non accompagnati

    Tra universalismo dei diritti e pluralità delle culture: il caso delle mutilazioni genitali femminili

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    La domanda sui diritti umani alla luce della pluralità delle culture investe il tema dei reati culturalmente motivati. Nel presente saggio ci si interroga sulla valutazione che il giudice può fare, ad esempio, a proposito delle mutilazioni genitali femminili. Tenendo conto del senso antropologico che contraddistingue i riti di passaggio, si auspica che il giudice si avvalga di altri saperi, segnatamente quello dell'antropologo al fine di valutare i comportamenti secondo un'ermeneutica diatopica

    Pulmonary lymphatic vessel morphology: a review

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    Our understanding of lymphatic vessels has been advanced by the recent identification of relatively specific lymphatic endothelium markers, including Prox-1, VEGFR3, podoplanin and LYVE-1. The use of lymphatic markers has led to the observation that, contrary to previous assumptions, human lymphatic vessels extend deep inside the pulmonary lobule, either in association with bronchioles, intralobular arterioles or small pulmonary veins. Pulmonary lymphatic vessels may thus be classified into pleural, interlobular (in interlobular septa) and intralobular. Intralobular lymphatic vessels may be further subdivided in: bronchovascular (associated with a bronchovascular bundle), perivascular (associated with a blood vessel), peribronchiolar (associated with a bronchiole), and interalveolar (in interalveolar septa). Most of the intralobular lymphatic vessels are in close contact with a blood vessel, either alone or within a bronchovascular bundle. A minority is associated with a bronchiole, and small lymphatics are occasionally present even in interalveolar septa, seemingly independent of blood vessels or bronchioles. The lymphatics of the interlobular septa often contain valves, are usually associated with the pulmonary veins, and connect with the pleural lymphatics. The large lymphatics associated with bronchovascular bundles have similar characteristics to pleural and interlobular lymphatics and may be considered conducting vessels. The numerous small perivascular lymphatics and the few peribronchiolar ones that are found inside the lobule are probably the absorbing compartment of the lung responsible for maintaining the alveolar interstitium relatively dry in order to provide a minimal thickness of the air-blood barrier and thus optimize gas diffusion. These lymphatic populations could be differentially involved in the pathogenesis of diseases preferentially involving distinct lung compartments

    Aufnahme läuft! Partizipative, sozio-technische Gestaltung digitaler Kommunikationssysteme

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    Der Beitrag beschäftigt sich mit einem Vorgehen zur partizipativen, sozio-technischen Gestaltung digitaler Kommunikationssysteme. Dieses Vorgehen wurde für ein konkretes Beispiel der Adoption eines Videokonferenztools in unserer Hochschule entwickelt und erprobt. Aus diesem Beispiel werden anschließend Best Practices für die partizipative, sozio-technische Systemgestaltung in Hochschulen abgeleitet

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Standardisierung und Harmonisierung sozio-demographischer Variablen

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    In der Umfrageforschung sind demographische und sozio-ökonomische Variablen in der Regel die unabhängigen Variablen. Für einen Vergleich von Einstellungen und Verhalten der Befragten über unterschiedliche Umfragen hinweg ist eine Standar­disierung der unabhängigen, der demographischen und sozio-ökonomischen Variablen zwingend erforderlich. Eine von den Dachverbänden der Umfragen durchführenden Gruppen: der akademischen Sozialforschung, der kommerziellen Markt- und Sozialfor­schung und der amtlichen Statistik eingesetzte Arbeitsgruppe hat für die Bundes­republik Deutsch­land ein entsprechendes Instrumentarium entwickelt und formuliert: die „Demogra­phischen Standards“, deren einzelne Variablen der derzeit aktuellen Ausgabe von 2010 hier beschrie­ben werden. Für den interkulturellen und internationalen Vergleich ist eine Standardisierung nicht möglich. Hier hilft nur eine Harmonisierung der einzelnen Variablen über die an der Umfrage beteiligten Kulturen oder Länder hinweg. Beschrieben werden die unter­schiedlichen Techniken der Harmonisierung und die Regeln, die bei deren Anwendung zu beachten sind

    Comparing Meanshift/SVM and Mask-RCNN algorithms for beach litter detection on UAVs images

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    Novel methodologies for beach litter monitoring take advantage of machine learning techniques applied to highresolution aerial-photogrammetric images acquired by unmanned aerial vehicles (UAV). In this study, a first attempt to classify multiple classes of litter items from very highresolution images derived from an aerophotogrammetric survey is proposed. For this purpose, a comparison between segmentation and classification algorithms is proposed for the automatic identification of beach macro-litter items (>2.5 cm). In particular, the Meanshift segmentation algorithm joined with the Support Vector Machine (SVM) classification algorithm were compared to a Convolutional Neural Network (Mask- RCNN). Two beach sectors, one on the Atlantic coast of Portugal and the other on the Adriatic coast of the Apulia region (Italy) were used as training site while test cases were conducted on the Italian site. Segmentation and classification phases were conducted considering three labels associated with three litter types. Results show a better performance of the Mask-RCNN algorithm with a precision value of 0.178 for 3 classes. The proposed comparison shows that algorithms based on Convolutional Neural Networks provide a useful tool for beach litter analysis programs and highlights how their training phase requires a specific survey plan to be followed during UAV image acquisitions

    Synthesis and Preliminary Evaluation of L-Dopa/Benserazide Conjugates as dual Acting Codrugs

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    The synthesis and “in vitro” chemical and enzymatic stability of Dopa/Benserazide conjugates (2 and 3) as dual acting codrugs are described. These codrugs possess a good lipophilicity (log P = -0.10) when compared to the parent drug LD and benserazide. Furthermore carbonyl and oxalyl spacers provide adequate stability in aqueous buffer solutions (pH 1.3 and 7.4). In 80% rat plasma at 37 °C, catechol esters and amide bonds of the studied derivatives were cleaved, and LD and benserazide were formed in one step. Our findings indicate that synthesized codrugs show good stability toward g.i. hydrolysis releasing LD and benserazide in rat plasma after enzymatic hydrolysis
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