1,721,572 research outputs found
Endobronchial ultrasound-guided transbronchial needle aspiration and tuberculosis mediastinal lymphadenopathy
The Role of Early Bronchoscopy in Stable Patients With Mild Hemoptysis: New Insights for Clinical Decision-Making
Contributo allo studio della fonologia delle iscrizioni latine della Sardegna paleocristiana
Il contributo contiene un esame linguistico, incentrato sulla fonetica, delle epigrafi latine rinvenute in Sardegna e risalenti ai secc. IV-VI d.C. Secondo il metodo inaugurato da J. Herman, si procede alla misurazione della rilevanza statistica delle diverse tipologie di "errore"; viene inoltre effettuata una comparazione con i dati ricavabili, per lo stesso periodo, dai titoli provenienti dalla Penisola Iberica, da Lione e da Vienna, dalla regio XI Italiae, da Roma, dall'Italia del Sud e dalla Dalmazia
In vitro susceptibility testing and totally drug-resistant tuberculosis
It is important to consider totally drug-resistant (TDR) tuberculosis (TB) cases as being curable. No case is incurable by definition; we need to re-enforce the message that, although difficult-to-treat, XDRTB cases can have concrete chances of winning their battle against the disease. This message is even more convincing now that we have much improved diagnostic tools e.g. GenXpert and new drugs, e.g. delamanid, bedaquiline and PA-824.
The present evidence on the extent of drug susceptibility testing, as of today, still provides suboptimal predictions for the in vivo effect of second-line anti-TB drugs and further research is needed. In addition, the real impact of the cocktail of anti-TB drugs prescribed on an individual basis is not fully clear. It is difficult, in fact, to attribute cause and effect to each specific drug and the design of prospective clinical trials is also difficult when dealing with XDR-TB and other complicated multidrug-resistant cases.
The therapeutic drug monitoring represents the future for improving the quality of second-line anti-TB drugs prescription. Any contribution in this direction will represent a significant step forward in improving patient management, optimising doses, minimising adverse events and, consequently, maximising the drugs’ effect
ELECTROCHEMICAL MICROSTRUCTURING OF SILICON SURFACES FOR FIELD EMISSION ENHANCEMENT
Parigi (F
Electrochemistry of ethyl alpha -bromo alpha -fluoro-phenylacetate, of some ethyl alpha -bromo trifluoro-methyl-phenylacetates and electrochemical synthesis of the corresponding diastereoisomeric diethyl succinates.
J. CHEM. RESEARCH (S), 1992, 321; J. CHEM. RESEARCH (M), 1992, 2732-2754
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