1,720,956 research outputs found
Valutazione del CD30L solubile circolante in pazienti con sclerosi sistemica
No full textValutazione del CD30L solubile circolante in pazienti con sclerosi sistemic
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Role of CD30 ligand (CD30L) positive T cells in the modulation of the inflammatory response in rheumatoid synovitis
No full textCD30 and CD30 ligand (CD30L) are members of TNF-Receptor and TNF superfamilies, respectively. T cells ex- pressing CD30 are increased in several human diseases and in- teraction of CD30L with CD30+ cells induces signals that cause cell proliferation or apoptosis. A percentage of lymphomonocytes from synovial fluid (SF) from patients affected by Rheumatoid Arthritis (RA) express surface CD30 and high levels of soluble CD30 (sCD30) have been shown both in sera and SF of RA pa- tients. The increase of sCD30 levels seems to reflect the recruit- ment of CD30+ T cells into the inflamed joints and is predictive of a positive response to immunosuppressive therapy. Recently a soluble form of CD30L has been described in RA patients’ sera. Our aim was to investigate the role of sCD30L in RA. Materials and Methods. We have used cells from peripheral blood and SF and sera from RA patients. RA patients were treat- ed either with DMARDs or TNFα blockade therapy. We have analysed the cell surface expression of CD30L in T lymphocytes from peripheral blood (PB) and SF of patients with RA and in Jurkat cell line by flow-cytometry. Samples were also tested for membrane expression of CD30, CD127 and for intracellular FOX-P3. CD30L surface expression was validated by RT-PCR of the CD30L gene and by Western Blot and by Immunoprecip- itation of the molecule from RA T lymphocytes. Soluble CD30L was detected by ELISA assay in sera and SF of RA patients.
Results. In PB and SF of RA patients a percentage of lympho- cytes expressed surface CD30L and CD30; CD30L and CD30 are not expressed on the same cells. CD30L+ T lymphocytes from SF did not show a Treg phenotype, while a percentage of CD30+ T lymphocytes was FOXP3+. Interestingly nearly 50% of CD4+/FOXP3+/CD127- cells are CD30+ cells. RT-PCR of the CD30L gene, Western Blot and Immunoprecipitation of CD30L from cells surface validated the presence of this molecule in lymphocytes of RA patients. sCD30L was not detectable in PB of healthy controls whereas it was present in PB and SF of patients with RA showing a correlation with the disease activity particularly in patients treated with TNFα blockade therapy. Conclusions. The expression of CD30L on the surface of a percentage of T lymphocytes from SF of patients affected by RA may reflect the Th1 pro-inflammatory response in this set- ting. The high levels of sCD30L both in sera and SF suggest that CD30L can be shedded as a functional active molecule as CD30 is. In this way sCD30L may induce apoptosis of CD30+ T cells leading to increased inflammation. Therefore, the cor- relation between the levels of this molecule and the response to TNFα-blockade therapy makes CD30L an interesting pre- dictor of response to the therapy itself
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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