1,720,975 research outputs found
Contributo della tecnica immunoistochimica per le Selectine per la soluzione di casi giudiziari
No full textL’indagine patologico-forense rappresenta una fase di criticità nella risoluzione
di casi criminalistici; i quesiti relativi alle cause, ma soprattutto ai mezzi
e all’epoca del decesso, ne rappresentano un nodo cruciale, che sempre di piú
oggigiorno necessita dell’integrazione dell’esame autoptico con le piú moderne
tecniche diagnostiche e di laboratorio quali, ad esempio, l’immunoistochimica,
che stanno offrendo un contributo sempre maggiore ai fini di una concreta risposta
ai quesiti posti dall’Autorità Giudiziaria. Il contributo analizza la tecnica
immunoistochimica per la ricerca delle Selectine, molecole di adesione coinvolte
nell’interazione leucociti-endotelio, ed in particolar modo la sua applicazione
pratica per la risoluzione di casi sottoposti ad indagine peritale
Decessi metadone-correlati: esiste una causalità esclusiva?
No full textLa terapia sostitutiva con metadone nei soggetti tossicodipendenti ha comportato problematiche sia di rilevanza medico-legale sia di tipo giuridico correlate con le difficoltà di inquadramento delle cause di morte nei soggetti assuntori di metadone. Tali difficoltà risiedono nella necessità di definire l’effettivo ruolo causale svolto da patologie e/o condizioni preesistenti del paziente e l’interazione con altre sostanze farmacologiche. In particolare nel loro lavoro gli Autori segnalano confermando quanto già di fatto riportato nella letteratura internazionale sul tema, la necessità di effettuare uno studio anatomopatologico sistematico che integri le indicazioni fornite dall’indagine chimico-tossicologica e i dati anamnestico-circostanziali.Methadone substitution therapy for drug The substitution of methadone for heroin abusers has arisen recently and has resulted in various problems of both medico-legal and juridical importancemedico-legal problems r. elated to These kind of problems the interpretation of methadone users deaths. These problemsare b concern the difficult definition of the actual causative role of the patient’s pre-existing pathologies and/or conditions and pharmacological interactions. In particular, in our report we decided to stress what the international literature already evidenced, that is the need of a systematic anatomical- pathology examination to integrate the informations given by the chemical-toxicological samples and circumstantial evidence.
oth of medical and juridical importance cause they usually concern methadone associated deaths or the prescription of methadone resulting in criminal prosecutions concerning physicians. We present the case in which a 40 year old adult female drug addict, died. Toxicological exams showed an acute intoxication of methadone in correlation with an extensive bilateral bronchopneumonia. This analysis is done using background informations concerning the management of alternative therapies and the available literature
Markers di cronologia delle lesioni e rilevanza di prova
No full textGli Autori effettuano una revisione critica degli studi, eseguiti sino ad oggi, concernenti la cronologia delle lesioni di interesse della patologia forense, focalizzando l'attenzione sulle caratteristiche che dovrebbe avere un parametro per assumere il valore di prova in giudizio. Le informazioni piú affidabili di ciascun marker sono sintetizzate in tabelle secondo la cronologia che evidenziano e le prospettive di ricerca future sono discusse
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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