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4. Abnormal spinal cord pain processing in Huntington's disease. The role of the diffuse noxious inhibitory control.
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Effects of low and high frequency repetitive transcranial magnetic stimulation of the primary motor cortex on contingent negative variations in normal subjects
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Effects of levetiracetam vs topiramate and placebo on visually evoked phase synchronization changes of alpha rhythm in migraine
Full text linkObjective: Recent theories about migraine pathogenesis have outlined an abnormal central processing of sensory signals, also suggested
by an abnormal pattern of EEG hyper-synchronization under visual stimulation. The aim of the present study was to test the efficacy of
topiramate and levetiracetam vs placebo in a double blind project observing the effects of the three treatments on the EEG synchronization
in the alpha band under sustained flash stimulation.
Methods: Forty-five migraine without aura outpatients (MO) were selected and randomly assigned to 100 mg topiramate, 1000 mg
levetiracetam or placebo treatment. In addition, 24 non-migraine healthy controls were submitted to EEG analysis. The EEG was
recorded by 19 channels: flash stimuli with a luminosity of 0.2 J were delivered, in a frequency range from 3 to 30 Hz. We evaluated
the phase synchronization index, that we previously applied in migraine, after EEG signals filtering in the alpha band. Our approach
was based on the Hilbert transform.
Results: Both levetiracetam and topiramate significantly decreased migraine frequency, compared with placebo. MO patients displayed
increased alpha-band phase synchronization as an effect of stimulus frequency; on the other hand the stimuli had an overall desynchronizing
effect on control subjects. The phase synchronization index separates the two stages, before and after the treatment, only for
levetiracetam, at stimulus frequencies of 9, 18, 24 and 27 Hz.
Conclusions: An abnormal alpha band synchronization under visual stimuli was confirmed in migraine; this phenomenon was reversed
by levetiracetam preventive treatment.
Significance: These results confirmed in humans the inhibiting action of levetiracetam on neuronal hyper-synchronization
Effects of distraction versus spatial discrimination on laser-evoked potentials in migraine
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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