1,720,962 research outputs found
Il ruolo della TEM nel trattamento dei tumori del retto extraperitoneale
No full textAfter Heald's revolution in 1982, who introduced the Total Mesorectal Excision, for improve the results in terms of recurrance and survival rate, there is a need to explore new therapeutic options in treatment of sub-peritoneal rectal cancer. In particular, local excision represent more often a valid technique for non advanced rectal cancer treatment in comparison with the more invasive procedure, especially in elderly and/or in poor health patients. The introduction of TEM by Buess (Transanal endoscopy Microsurgery), has extended the local treatment also to classes of patients who would normally have been candidates for TME. The author gives literature's details and his experience in the use of TEM for early rectal cancer sub-peritoneal. The aim of the study is to analyze short and long term results in terms of local recurrence and survival rate comparing TEM technique with the other transanal surgery in rectal cancer treatment. Preoperative Chemio-Radio therapy and rigorous Imaging Staging are the first steps to planning surgery. It's time, for local rectal cancer, has come to make the devolution a few decades ago has been accomplished in the treatment of breast cancer
Breast myofibroblastoma in a young woman. A case report
No full textIl Miofibroblastoma (MFB) è un raro tumore mesenchimale benigno che può insorgere in molti organi o tessuti. Sebbene molti casi riportati in Letteratura sono descritti a livello mammario, esso è estremamente raro, rappresentando meno del 1% di tutti i tumori della ghiandola mammaria. Il MFB è prevalentemente riscontrato negli uomini adulti, tuttavia alcuni casi sono anche stati descritti in donne in età menopausale. Il MFB è annoverato tra i tumori di origine stromale e mostra diverse varianti morfologiche includendo quella a tipo cellulare, a fibre di collagene, epitelioide, a palizzata, lipomatosa, tipo emangiopericitoma e in ultimo quella infiltrante. Anche se la sua incidenza è recentemente aumentata a causa dello screening mammografico, solo pochi casi sono stati descritti in Letteratura e ancora meno in donne in giovane età. L’esame obiettivo mostra un singolo nodulo, unilaterale, non doloroso, mobile sui piani sottostanti e di consistenza dura. Le indagini radiologiche non sono specifiche per giungere ad una corretta diagnosi preoperatoria. Inoltre anche i reperti ottenuti mediante aspirazione con ago sottile potrebbero generare confusione rendendo di fatto possibile la diagnosi di MFB soltanto all’esame istologico definitivo analizzando il pezzo operatorio asportato chirurgicamente. Nessuna evidenza di trasformazione maligna, recidiva o metastasi a distanza dopo un periodo di follow-up di 15 anni sono state descritte in Letteratura quando i margini di escissione sono risultati liberi da malattia. Di seguito gli Autori descrivono un raro caso di MFB della mammella in una giovane donna.Myofibroblastoma (MFB) is an uncommon benign mesenchymal tumor that may arise in several organs and tissue. Although most of reported cases were located in the breast, it is extremely rare, representing less than 1% of breast tumor. MFB has predominantly seen in elderly men, but some cases have been described in menopausal women. This lesion is a stromal tumor which has many morphologic variants including cellular, collagenized, epithelioid, palisaded, lipomatous, hemangiopericytoma-like, and infiltrant features. Even if its incidence has recently increased due to the mammary screening, only few cases have been reported in Literature and even less in young women. Physical examination discloses a solitary, unilateral, painless, freely movable, usual firm in consistency, non-tender nodule. Imaging investigations usually are not specific to establish the right diagnosis. Furthermore, findings from Fine-Needle Aspiration (FNA) may be confusing and nonspecific, making diagnosis of MFB possible only after surgical operation. Not evidence of malignant transformation, recurrence or distant metastasis after a follow-up period of 15 years have been reported in Literature when resection margins are free. Hereby the authors describe a rare case of breast MFB in a young woman
Self-expandable metal stents in the treatment of benign anastomotic stricture after rectal resection for cancer
No full textAimTo evaluate the use of self-expandable metallic stents to treat patients with symptomatic benign anastomotic stricture after colorectal resection. MethodTen patients with a benign symptomatic anastomotic stricture after colorectal resection were treated with endoscopic placement of a self-expandable metal stent. ResultsThe stent was placed successfully in all 10 patients without any major morbidity. At a mean follow-up of 18months the stenosis was resolved successfully in 7 out 10 patients (70%). The remaining three patients were subsequently treated successfully with balloon dilatation. ConclusionSelf-expandable metal stents represent a valid alternative to balloon dilatation to treat patients with benign symptomatic anastomotic stricture after colorectal resection for cancer
Self-expanding metal stents for treatment of anastomotic complications after colorectal resection
No full textSelf-expanding metal stents (SEMS) can be used to treat patients with symptomatic anastomotic complications after colorectal resection. In the present case series, 16 patients with symptomatic anastomotic stricture after colorectal resection were treated with endoscopic placement of SEMS. Seven patients had a "simple" anastomotic stricture and nine patients had a fistula associated with the stricture. The anastomotic fistula healed without evidence of residual stricture or major fecal incontinence in seven of the nine patients. Overall the anastomotic stricture was resolved in 10 of the 16 patients. SEMS placement represents a valid adjunctive to treatment in patients with symptomatic anastomotic complications after colorectal resection for cancer
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Laparoscopic transperitoneal anterior adrenalectomy
No full textAIM:
Aim of this study was to report the authors' experience with the anterior transperitoneal approach, and with an anterior submesocolic approach in case of left sided lesions.
MATERIAL AND METHODS:
From January 1994 to January 2011, 122 males and 170 females with a mean age of 50.7 years (range: 19-84) underwent laparoscopic adrenalectomy (LA) at 2 centers in Ancona and Rome (Italy) (that follow the same protocol). Fifteen patients underwent bilateral LA, the anterior transperitoneal approach was used in 233 cases (79.8%) and the anterior submesocolic in 59 (20.2%). One hundred and two patients had Conn's syndrome, 51 miscellaneous lesions, 55 Cushing's syndrome, 47 incidentalomas, 46 pheochromocytoma, 2 metastatic masses, 2 myelolipomas and 2 adrenogenital syndromes. The lesions had a mean diameter of 3.24 cm (range: 0.5-10).
RESULTS:
Mean operating time was 120 minutes (range: 30-390). Conversion to open surgery was required in 13 cases (4,45%). Blood pressure and heart rate were stable during the operation. There were 5 major complications. Mobilization and resumption of diet occurred on the first postoperative day. Mean hospital stay was 4.32 days (range: 2-30).
DISCUSSION:
Early identification and ligature of the adrenal vein, with minimal gland manipulation, are the major advantages, especially in case of pheochromocytoma.
CONCLUSIONS:
Adrenal masses can be successfully treated using a laparoscopic transperitoneal anterior approach, in presence of a suitable anesthesiological and surgical team's experience
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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