1,720,979 research outputs found
Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients.
No full textOcular findings in X-linked ichthyosis: A survey on 38 cases
No full textThe authors report on the occurrence of ocular abnormalities in X-linked ichthyosis (XLI) patients, in their carrier mothers and in healthy volunteers who served as controls. The diagnosis of XLI was based on: (1) demonstration of steroid sulfatase deficiency in cultured skin fibroblasts; (2) lack of hybridization of patient’s deoxyribonucleic acid (DNA) with specific steroid sulfatase complementary DNA probe; (3) electrophoretic mobility of plasma lipoproteins. Cholesterol sulfate plasma levels were also determined. The incidence of corneal opacities was the same in XLI patients and in their carrier mothers (23.7 and 24.3%, respectively). Neither other corneal nor ophthalmological alterations were found. Moreover, in XLI patients the plasma levels of cholesterol sulfate were about twenty times higher than in controls. Our findings demonstrate that ocular changes do not seem to be an absolute criterion for a definite diagnosis of XLI and the fact that the pathogenesis of corneal opacities is not due to an accumulation of cholesterol sulfate, but rather that this compound probably induces physicochemical changes of the corneal tissue properties
THE TAKAGI AUTOMATIC TANGENT SCREEN ATS-85 ANALYZER FOR THE DETECTION OF GLAUCOMATOUS PATIENTS
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Epidural analgesic infusion in pain control: handy and safety use of elastomeric infusor.
No full textEffect of oral bromocriptine administration on intraocular pressure in normotensive and glaucomatous human subjects
No full textPURPOSE: The authors have verified the effect of orally administered bromocriptine on intraocular pressure in normotensive and glaucomatous human subjects.
METHOD: Fifteen healthy volunteers and 15 glaucomatous patients were studied. Intraocular pressure, pupil diameter, total outflow facility, systolic arterial pressure, diastolic arterial pressure, and heart rate were recorded at baseline and at 1-h intervals for 12 h after oral administration of 2. 5 mg bromocriptine or placebo, given in a randomized, double-masked, cross-over fashion. The alternate regimen was given a week later.
RESULTS: In all subjects bromocriptine significantly reduced intraocular pressure, whereas no variations in pupil diameter, systolic and diastolic arterial pressures, and heart rate were recorded. Moreover, total outflow facility, measured by conventional tonography, increased significantly both in normotensive and glaucomatous eyes.
CONCLUSIONS: These findings indicate that oral bromocriptine administration could represent a new therapy to reduce intraocular pressure in human
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