1,720,983 research outputs found
Cytological grading of canine cutaneous mast cell tumours
No full textcytological grading for mast cell tumours (MCTs) would be highly desirable, allowing to select the most appropriate therapeutic intervention prior to surgery. This study evaluates the applicability on fine-needle aspirations (FNAs) of the novel Kiupel grading system, based on number of mitoses, multinucleated cells, bizarre nuclei and presence of karyomegaly. Fifty consecutive cases with pre-operative cytological diagnosis were included. In cytological specimens, approximately 1000 cells were evaluated, and the histological grade was assessed on the corresponding resected specimens. On cytology, the above parameters were significantly different between histologically low-grade and high-grade tumours (P<0.001). The cytograding correctly predicted the histological grade in 47 cases (accuracy, 94%; sensitivity, 84.6%; specificity, 97.3%). Two high-grade MCTs (4%) were not detected on cytology. The cytograding can provide helpful insights to assist clinical decisions in most cases. However, the risk of underestimation in a minority of patients represents a limit to the overall utility of the technique. © 2014 John Wiley & Sons Ltd
Pathology in Practice
No full textPathology in practice: case report of a Young dog affected by CNS neosporosis. The case report is described according to the modalities of "what is your diagnosis". A young adult 12-kg (26.4-lb) female mixedbreed dog housed in an animal shelter was referred to the teaching hospital of the Department of Veterinary Medical Sciences of the University of Bologna because of severe nonambulatory tetraparesis and abnormal mentation. The dog was found wandering 2 months before; at that time, the dog had mild paraparesis that slowly progressed to tetraparesis and recumbency. On neurologic examination, the
dog was in lateral recumbency with severe nonambulatory tetraparesis, obtunded mental status, leftsided head tilt, occasional tremors of the neck and
head, and spontaneous proprioceptive deficits in all 4 limbs. Cranial nerve examination revealed vertical spontaneous nystagmus and an abnormal menace response. History and clinical signs were consistent with a suspected multifocal neurologic disorder, primarily involving the brainstem. Serum and CSF samples were tested for antibodies against Toxoplasma spp and Neospora spp. Both samples were negative for Toxoplasma spp but strongly positive
for Neospora spp (in both samples, the IgG titer was 1:640 (reference interval applied to both serum and CSF, < 1:40). A PCR assay was performed on the CSF sample, and the result was positive for Neospora caninum. On post mortem examination, sections of the brain (cerebral cortex) revealed
that neuroparenchyma was affected by multifocal malacia and reactive gliosis associated with intralesional groups of protozoa; numerous deeply basophilic bradyzoites measuring 6.5 X 1.5 μm were present, often within the cytoplasm of glial cells. There was evidence of nonsuppurative lymphoplasmacytic meningoencephalitis and reactive gliosis; samples of the cerebellum and brainstem contained scattered cysts without septa, with a wall thickness
of 0.5 to 4 μm. Ultrastructural examination of brain and cerebellum revealed bradyzoites grouped together and not enclosed by a cyst wall; intact bradyzoites had an apical part (conoid) rich in micronemes, rhoptries with an electron-dense content, electron-lucent amylopectin granules, and a nucleus , supporting the etiologic diagnosis of neosporosis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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