1,720,990 research outputs found
Caratterizzazione della reattività naturale cellulo-mediata indotta da ciclofosfamide verso la Candida albicans nel topo
No full textImmunomodulation of murine natural peritoneal cytotoxicity by polysaccharides produced by streptococci indigenous to man.
No full textEffects of multiple treatments with biological response modifiers on development of NK/LAK activity in mice
No full textEffects of hydrogen peroxide on both proliferative capacity and vitality of different animal species lymphocytes
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Learning from other diseases: protection and pathology in chronic fungal infections
No full textFungal commensals coexist in a complex milieu of bacteria within the human body. An increased understanding of the importance of microbiota in shaping the host’s immune and metabolic activities has rendered fungal interactions with their hosts more complex than previously appreciated. Metagenomics has revealed the complex interactions between fungal and bacterial commensals that, either directly or through the participation of the host immune system, impact on immune homeostasis at mucosal surfaces that, in turn, lead to secondary fungal infections. Metabolomics has captured the dialogue between the mammalian host and its microbiota. It appears that the host tryptophan catabolic enzyme, indoleamine 2,3-dioxygenase 1 (IDO1) plays a dominant role in the interplay between tryptophan catabolism by microbial communities, the host’s own pathway of metabolite production, and the activation of the aryl hydrocarbon receptor (AhR)/IL-22 axis, eventually impacting on mucosal immune homeostasis and host/fungal symbiosis. Thus, the regulatory loop involving AhR and IDO1 may be exploited for the development of multi-pronged host- and microbiota-directed therapeutic approaches for mucosal and systemic fungal diseases
Frazioni purificate della parete di C. albicans come modulatori in vivo dell'attività delle cellule LAK
No full textEffect of inactivated C. albicans on natural killer (NK) cell activity and blastogenesis in mice. P. Marconi, L. Scaringi, A. Cassone, L. Tissi. In: Genetic and Phenotypic Markers of Tumors, (S.A. Aaronson, L. Frati and R. Verna Eds.). Plenum Publishing Corp., New York, London, pp. 145-151, 1985.
No full textInduzione di cellule NK e LAK in vivo: confronto fra la C. albicans ed alcuni "biological response modifiers"
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