1,720,966 research outputs found
La carriera lavorativa nell'era dell'employability: un contributo di ricerca sui nuovi orientamenti di carriera.
No full textIl presente contributo di ricerca si pone l’obiettivo di fornire un apporto empirico allo studio dei modelli Boundaryless e Protean Careers in relazione ad alcune variabili connesse alla carriera lavorativa, quale il Career Commitment, variabile legata alle motivazioni individuali verso la propria carriera, e l’Employability Activities, variabile relativa all’impegno degli individui verso attività di sviluppo professionale, determinando un modello di ricerca utile allo studio dei nuovi orientamenti di carriera in tempi di flessibilità e a interventi di counseling. I risultati ottenuti su 260 partecipanti mostrano relazioni empiriche tra i costrutti evidenziando un maggiore adattamento del modello di ricerca al campione di partecipanti con una tipologia di carriera frammentata rispetto a chi ha avuto una carriera lineare in una stessa organizzazione
Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: A meta-analysis of randomized controlled trials
No full textObjective: To evaluate the effect of body weight (BW) on safety and efficacy of direct oral anticoagulants (DOACs).
Methods: We performed a meta-analysis of randomized controlled trials (RCTs) comparing DOACs with vitamin K antagonists (VKA) in patients with venous thromboembolism (VTE). Efficacy (prevention of recurrent VTE or VTE-related death) and safety (occurrence of major or clinically relevant non-major bleeding) outcomes were stratified according to patients' BW (low, normal, and high).
Results: Six RCTs with a total of 27,023 patients were included. DOACs showed a similar efficacy to VKA in patients with high BW, normal BW, and low BW (RR 0.98, 95% CI 0.72, 1.35; RR 0.91, 95% CI 0.75, 1.09; and RR 0.84, 95% CI 0.57, 1.24, respectively). Safety was comparable among DOACs and VKA in patients with high BW and low BW (RR 0.93, 95% CI 0.65, 1.32; and RR 0.80, 95% CI 0.54, 1.20), whereas DOACs were marginally safer than VKA in normal-BW subjects (RR 0.82, 95% CI 0.67, 1.00). However, the difference among DOACs and VKA in the rate of bleeding episodes appeared similar in the three BW groups.
Conclusions: Results of our meta-analysis suggested that DOACs might be a safe and effective therapeutic option for the treatment of acute VTE even in the patients with extreme body weights. However, other studies with larger study populations are warranted to confirm our findings
Repeated low-dose courses of rituximab in SLE-associated antiphospholipid syndrome: Data from a tertiary dedicated centre
Full text linkWereadwithinteresttherecentarticlebyWangandLiu [1],
describing theirexperiencewithrituximab(RTX)in6systemic
lupus erythematosus(SLE)-associatedantiphospholipidsyndrome
(APS) patients.Thesedatasupporttheideathat,inlinewith
previoussporadiccasesreportedinliterature,RTXatdifferent
regimensisabletoreducethromboticrecurrencesandtoimprove
SLE activity,withanoverallgoodsafetyprofile. Moreover,they
confirm thedisappearance/decreaseoftiterofantiphospholipid
antibodies afterRTX [1]
Antithrombotic drugs, patient characteristics, and gastrointestinal bleeding: Clinical translation and areas of research
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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