1,721,019 research outputs found
Tridentate N-N-N chelating systems as potential antitumor agents [Sistemi chelanti tridentati N*-N*-N* quali potenziali agenti antitumorali]
No full textTridentate chelating agents, as potential antitumor agents, were prepared by condensing 2-quinolylhydrazines, 2-pyridylhydrazine and 2-benzothiazolylhydrazine with pyridine-2-aldehyde, 6-methylpyridine-2-aldehyde, 2-acetylpyridine and 2-benzoylpyridine. All compounds were tested against Lymphocytic leukemia P388. The active pyridine-2-aldehyde-4-methyl-2-quinolylhydrazone [1-(4'-methyl-2'-quinolyl)-3-(2'-pyridyl)-1,2-diaza-2-propene] (I d) was also tested against other experimental tumors and proved inactive
Characterization of Brassica fruticulosa seeds
No full textThe structure and vitamin E (tocopherol and tocotrienol), fatty acid and phytosterol content and composition of seeds of Brassica fruticulosa Cyr. (Brassicaceae) were characterized. Seed size and elevated content of γ-tocotrienol, and γ- tocopherol and low of α- tocopherol can be useful for distinguishing seeds of B. fruticolosa from those of Sicilian Brassica sect. Brassica. The concentration of the tocotrienol is about one third of the vitamin E content. This profile makes this wild species worth to be recovered as food source and its germplasm preserved in a gene bank
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Thin layer chromatography in pharmaceutical quality control. Assay of inosiplex in different pharmaceutical forms
No full textThe authors describe an HPTLC concentration zone method developed for the quality control of Inosiplex in different pharmaceutical forms. The plates were found to have good operating capacity in terms of specificity, accuracy, reliability and reproducibility with respect to the three molecular components of the active principle. The coefficients of variation of inosine and p-aminobenzoic acid are between 0.5 and 0.7. The method was also satisfactory for the quality control of 1-(dimethylamino)-2-propanol. Also if evidentiation is performed directly on the eluted spot, the coefficients of variation are between 1.2 and 1.6 for the three pharmaceutical forms
How safe is underground natural gas storage?Gas Storage Delta-Pressure: Story of a Successful Application.
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