1,720,981 research outputs found
Encefalopatia di Hashimoto: un'encefalopatia epilettogena transitoria?
No full textCL., donna di 62 anni, di origine filippina, emigrata in Italia da oltre 20 anni, diabetica con anamnesi negativa per precedenti epilettici e/o per altre patologie di rilievo, viene ricoverata per severo stato confusionale postcritico persistente a 72 ore dall'esordio. Al momento del ricovero sono presenti un grave disordine confabulatorio e sintomi dispercettivi sia acustici sia visivi; la paziente riferisce intensa cefalea diffusa e presenta una regressione linguistica, consistente nella capacità di esprimersi esclusivamente nella sua lingua d'origine, benché i familiari confermino una completa padronanza della lingua italiana
Modelli e Metodiche innovative nella Valutazione Dinamica di Neurofarmaci
No full textUniversità degli Studi di Napoli Federico II consorziata con Università degli studi di Bar
Comparison of levetiracetam and lamotrigine in late-onset epilepsy
No full textPurpose: To compare the efficacy and safety of add-on treatment of levetiracetam (LEV) and lamotrigine (LTG) in elderly patients with epilepsy. Methods: LEV or LTG were randomly assigned (1:1) to aged epilepsy patients clinically uncontrolled on antiepileptic drug (AED) monotherapy regimens. Patients were assessed fora 12 month followup period by means of diaries, side-effect scales, EEG and neuropsychological tasks. Results: At 12 month evaluation 5 (25%) patients undergoing LEV and 2 (10%) undergoing LTG were seizure-free. Seizure reduction > 50% was seen in 14 of 20 (70%) patients receiving LEV and in 4 of 20 (20%) receiving LTG. 2 patients premature1y discontinued LEV due to side effects an d 5 discontinued LTG for lack of efficacy or side effects. At the end of the study seizure-free subjects, after discontinuation of the first AED, underwent a further 12 month monotherapy follow-up. Conclusion: Our evidence suggests that efficacy/safety of LEV in elderly patients may be in some instances superior to those observed far LTG. LEV could also have substantial potential use in the elderly as monotherapy proposal because of its easy and fast titration and lack of drug interactions
Effect of propranolol in head tremor: quantitative study following single-dose and sustained drug administration
No full textPrimidone in the long-term treatment : a pospective study with computerized quantitative analysis
No full textClinical and computer-based assessment of long-term therapeutica efficacy of propranolol in essential tremor
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