6,119 research outputs found
Platelet activation with unfractionated heparin at therapeutic concentrations and comparison with low-molecular weigh heparin and with a direct thrombin inhibitor
No full textInteraction between human platelet factor 4 and protamine sulfate in the presence of a low molecular weight heparin in the rabbit.
No full textEffect of recombinant-tissue plasminogen activator, low molecular weight urokinase and unfractionated heparin on platelet aggregation.
No full textWe studied the interaction of two thrombolytic agents, recombinant-tissue plasminogen activator (r-TPA) and low molecular weight urokinase (UK), with platelet aggregation in the absence or presence of unfractionated heparin (UH). With platelet rich plasma (PRP), a dose dependent inhibition was seen for both r-TPA and UK. However, this effect was more evident in the presence of r-TPA. UH did not modify this effect. However, it enhanced platelet aggregation induced by ADP and decreased the aggregation induced by collagen (COL) as already shown by us. With washed platelets, only r-TPA decreased platelet aggregation in a dose dependent manner in the presence of COL and only at the highest dose (100 micrograms) in the presence of TH. The presence of ten units of plasminogen (PLG) together with 10 micrograms of r-TPA or 1250 units of UK totally inhibited TH-induced platelet aggregation. UH reversed this effect. In contrast, when COL was the aggregating agent, the inhibition of platelet aggregation in presence of PLG, seems to be further increased by UH. Since UH is an adjunct of thrombolytic therapy to prevent rethrombosis, this double edged sword could partially explain the lack of therapeutic effect in some patients
COMMERCIAL 584\AA PHOTOELECTRON SPECTROMETER
No full textAuthor Institution: Perkin-Elmer LimitedThe design of a commercial 584\AA Photcelectron Spectrometer will be discussed together with some recent research problems investigated by this technique
Open Access to Peer-Reviewed Research through Author/Institution Self-Archiving: Maximizing Research Impact by Maximizing Online Access
No full textAll refereed journals will soon be available online; most of them already are. This means that anyone will be able to access them from any networked desk-top. The literature will all be interconnected by citation, author, and keyword/subject links, allowing for unheard-of power and ease of access and navigability. Successive drafts of pre-refereeing preprints will be linked to the official refereed draft, as well as to any subsequent corrections, revisions, updates, comments, responses, and underlying empirical databases, all enhancing the self-correctiveness, interactivity and productivity of scholarly and scientific research and communication in remarkable new ways. New scientometric indicators of digital impact are also emerging <http://opcit.eprints.org> to chart the online course of knowledge. But there is still one last frontier to cross before science reaches the optimal and the inevitable: Just as there is no longer any need for research or researchers to be constrained by the access-blocking restrictions of paper distribution, there is no longer any need to be constrained by the impact-blocking financial fire-walls of Subscription/Site-License/Pay-Per-View (S/L/P) tolls for this give-away literature. Its author/researchers have always donated their research reports for free (and its referee/researchers have refereed for free), with the sole goal of maximizing their impact on subsequent research (by accessing the eyes and minds of fellow-researchers, present and future) and hence on society. Generic (OAi-compliant) software is now available free so that institutions can immediately create Eprint Archives in which their authors can self-archive all their refereed papers for free for all forever <http://www.eprints.org/>. These interoperable Open Archives <http://www.openarchives.org> will then be harvested into global, jointly searchable "virtual archives" (e.g., <http://arc.cs.odu.edu/>). "Scholarly Skywriting" in this PostGutenberg Galaxy will be dramatically (and measurably) more interactive and productive, spawning its own new digital metrics of productivity and impact, allowing for an online "embryology of knowledge.
Author attribution using profile classifiers
No full textA atribuição autoral (AA) busca identificar um autor de texto a partir de um conjunto de autores conhecidos. Autores deixam rastros em seus textos e é possível identificar características sociolinguísticas baseadas no estilos de escrita refletidos no texto destes autores. A atribuição autoral está cada vez mais demonstrando importância para diversas atividades sociais, em especial para a análise forense. Os trabalhos envolvendo AA demonstram resultados modestos e motivam a exploração de diferentes técnicas para melhorar a acurácia dos modelos atuais. A partir desses pontos, o presente trabalho apresenta uma proposta de pesquisa em nível de mestrado no campo de processamento de língua natural (PLN), com ênfase em AA, com o objetivo geral de melhorar o desempenho de classificadores de atribuição autoral utilizando técnicas de caracterização autoral (CA)Author attribution (AA) seeks to identify a text author from a set of known authors. Authors leave traces in their texts and it is possible to identify sociolinguistic characteristics based on the writing styles reflected in the text of these authors. Author attribution is increasingly showing importance for various social activities, especially forensic analysis. Studies involving AA show modest results and motivate the exploration of different techniques to improve the accuracy of current models. From these perspective, this project presents a master\'s level research proposal in the field of natural language processing (NLP), with an emphasis in AA, with the general objective of improving the performance of AA classifiers using author profiling technique
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Observations of the 57Fe+23 hyperfine transition in clusters of galaxies
No full textWe present a search for the hyperfine transition of the 57Fe+23 ion at 3.071 mm in clusters of galaxies with the ATNF Mopra telescope. The results are compared with a realistic estimate of the peak brightness temperature of the line in a cooling flow cluster A85, using the available X-ray data
THE ANALYSIS OF FIVE ELECTRONIC EMISSION SYSTEMS OF NIOBIUM NITRIDE (NbN) IN THE REGION 5000{\AA} – 6200{\AA}
No full textK. H. Rao and T. M. Dunn, Nature 222, 266 (1969). J. L. Femenias, C. Athenour, and T. M. Dunn, J. Chem. Phys. 63, 2861 (1975).Author Institution:Niobium nitride emission systems have been found at 5l37{\AA}, 5582{\AA}, 5740{\AA}, 5840{\AA}, 5860{\AA}, in addition to the already systems with subbands at 5930{\AA}, 6043{\AA}, and 6192{\AA}. Most of These systems show marked nuclear hyperfine structure of the rotational lines add this has been of assistance in the analysis of all of the systems. Systems of triplet-triplet, singlet-singlet and singlet-triplet are all present and the hyperfine structure also allows assignment of the ground and excited state electron configuration to be made with some confidence
THE 4550 {\AA} BAND SYSTEM OF GLYOXAL
No full textAuthor Institution: Division of Pure Physics, National Research Council“Approximately 45 bands of glyoxal in the region 4000-4660 {\AA} have been photographed in absorption using a 30 ft. Ebert spectrograph with a resolving power of and a dispersion of 1.3 {\AA}/cm. The (0-0) baud near 4550 {\AA}, which WAS studied at a temperature of C, shows fairly well-resolved J- and K- structure characteristic of a perpendicular hand of a near symmetric top molecule. The rotational and vibrational analysis of the speetrum will be discussed.
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