186,234 research outputs found
Activity of daptomycin against enterococci and coagulase-negative staphylococci (CNS): relationship between CNS susceptibility and slime production
No full textLong-term follow-up evaluation of magnetic resonance imaging in the prognosis of permanent GH deficiency.
No full textCompeting C═O···C═O, C–H···O, Cl···O, and Cl···Cl Interactions Governing the Structural Phase Transition of 2,6-Dichloro-p-benzoquinone at Tc=122.6 K
No full text2,6-Dichloro-p-benzoquinone (DCBQ) has been investigated by single-crystal X-ray diffraction experiments in the T range of 300−21 K and quantum-mechanical simulations. A reversible monoclinic (high-T) to triclinic
(low-T) phase transition has been detected at Tc = 122.6(5) K. The various
noncovalent interactions (NCIs) that determine the solid-state self recognition of DCBQ have been characterized as a function of T through
the quantum theory of atoms in molecules. On lowering T, carbonyl−carbonyl interactions progressively strengthen, inducing a change in the crystal structure, while the dipolar C−Cl···O=C NCIs and the relatively strong Cl···Cl halogen bonds (XBs) and CH···O hydrogen bonds play an essential, but ancillary, role. Dispersive forces cooperate with other closed-shell dipolar NCIs, and particularly with XBs, in determining their overall attractive character, even when bulky and positively charged chlorine atoms are drawn closer and closer at low temperatures. The intermolecular interaction energies have been evaluated above and below Tc as sums of electrostatic, repulsion, and dispersion contributions
Long-term follow-up evaluation of magnetic resonance imaging in the prognosis of permanent GH deficiency.
No full text4814. Storia di Milano, scritta da Giovanni Pietro Cagnola, castellano délla rocca di Sartirana, en partie publiée par C. Cantù dans Archivio storico italiano, Ire série, 1842, t. III, p. 1-215
No full text4814. Storia di Milano, scritta da Giovanni Pietro Cagnola, castellano délla rocca di Sartirana, en partie publiée par C. Cantù dans Archivio storico italiano, Ire série, 1842, t. III, p. 1-215. In: Molinier Auguste. Les Sources de l'histoire de France - Des origines aux guerres d'Italie (1494). V. Introduction générale - Les Valois (suite), Louis XI et Charles VIII (1461-1494) Paris : A. Picard et fils, 1904. p. 63
Circulating levels of interleukin 1 beta and of interleukin 1 receptor antagonist in systemic juvenile chronic arthritis.
No full textTo measure circulating interleukin 1 beta (IL-1 beta) and IL-1 receptor antagonist (IL-1Ra) levels in patients with systemic juvenile chronic arthritis (JCA) and to evaluate their correlation with disease activity.IL-1 beta and IL-1Ra levels were measured by ELISA in 45 patients with JCA (20 systemic, 10 polyarticular and 15 pauciarticular) and in 15 healthy controls.Plasma IL-1 beta levels were undetectable in the majority of patients with systemic JCA, and detectable levels were not associated with different treatments or with parameters of disease severity. Serum IL-1Ra levels were markedly increased in patients with systemic JCA and significantly correlated with the persistence of systemic features, the extent and severity of joint involvement, and with C-reactive protein concentrations. Serum IL-1Ra levels were also significantly correlated with IL-6 levels.These results argue against a relevant role of IL-1 in systemic JCA. The increase in IL-1Ra levels does not appear to reflect an increase in IL-1 production, but may rather be induced by IL-6
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Differences in synovial fluid cytokine levels between juvenile and adult rheumatoid arthritis
No full textObjective. To evaluate quantitative or qualitative differences in synovial fluid (SF) cytokine levels among patients with systemic juvenile rheumatoid arthritis (JRA), antinuclear antibody positive pauciarticular JRA, or adult RA. Methods. SF levels of interleukin 1 alpha(IL-1 alpha), IL-1 beta, IL-1 receptor antagonist (IL-1Ra) IL-11, tumor necrosis factor-alpha (TNF-alpha), soluble TNF receptor 1 (sTNFR1), leukemia inhibitory factor (LIF), all measured by immunoassays, and of IL-6, measured with a bioassay using B9 cells, were evaluated in 11 patients with systemic JRA, 24 with pauciarticular TRA, and 22 adult patients with RA. Results. SF IL-6 levels were significantly higher in patients with systemic JRA than patients with pauciarticular JRA (p = 0.003) or RA(p = 0.002). IL-1 alpha was detectable in 12/24 SF samples from pauciarticular JRA, in 2/22 SF from RA, and in no sample from systemic JRA (p = 0.004 vs RA; p = 0.005 vs systemic JRA). SF IL-11 levels were significantly higher in patients with RA than patients with systemic JRA (p = 0.012) or pauciarticular JRA (p = 0.005). We found no significant differences in SF levels of IL-1 beta, IL-1Ra, TNF-alpha, sTNFR1, or LIF. Conclusion. In systemic JRA, SF levels of IL-6 are significantly higher than in pauciarticular JRA or in RA; IL-1 alpha is present in a significant proportion of patients with pauciarticular JRA, but not in those with RA or systemic JRA
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Parental investment in two large raptors breeding in a high prey density area
No full textWe investigated the breeding behaviour of Bearded Vulture Gypaetus barbatus and Golden Eagle Aquila chrysaetos between 2008 and 2011 in the Stelvio National Park (the Alps, Italy), which harbours one of highest densities of wild ungulates in the Alps. Parental care behaviours (incubation and chick brooding, nest attendance, changeover, food provisioning and nestling feeding) were recorded at nests of both species (four Bearded Vulture and 14 Golden Eagle pairs). Differences in investment between sexes and periods were found in both species: the time spent in incubation and nest attendance was higher in females and decreased with the progress of the breeding season (from incubation to post-hatching and to pre-fledging). A significant effect of the interaction between sex and period was also found. Compared to the literature, our results suggest a lower contribution by Bearded Vulture males, whereas Golden Eagle males spent more time in incubation and nestling brooding than reported. The higher investment shown by Golden Eagle males in our study area may be due to the high availability of live prey and ungulate carrion, which could allow males to spend less time in hunting, resulting in more time at the nest. Most changeovers for both species took place in the central hours of the day. No difference in food provisioning was observed between the sexes of the two species, consistent with information available for Bearded Vultures, but not for Golden Eagles. The patterns we found revealed a female-biased investment (unexpected for the Bearded Vulture), although males significantly contributed to nest behaviour, especially during the incubation period (unexpected for Golden Eagles). The large amounts of natural prey and carrion in the study area may contribute to the nest behaviour of these large raptors
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