1,721,046 research outputs found
Topical application of DMSO as an adjunct to tissue expansion for breast reconstruction.
No full textPharmacological enhancement of cutaneous flap survival with topical dimethyl sulphoxide and hydrogen peroxide.
No full textThe present study was designed to investigate, in a rabbit model, the value of topical application of a solution of hydrogen peroxide (H2O2) 8% + dimethyl sulphoxide (DMSO) 50% in order to reduce ischaemic failure in random skin flaps. Two parallel, cephalad-based para-midline random cutaneous flap (10 cm x 2.5 cm) were elevated and resutured in place on the dorsum of 40 New Zealand rabbits. The 80 flaps thus obtained were then randomly divided into one control group and three experimental groups of 20 flaps each. Flaps from the control group (Group A) were topically treated with saline, while flaps from experimental Group B were treated with H2O2 8%, flaps from experimental Group C with DMSO 50%, and flaps from experimental Group D with a solution of 50% DMSO + 8% H2O2. Each solution was topically applied to the flaps, 20 ml three times a day for 7 days, starting in the immediate postoperative period. Transcutaneous oxygen tension (PtcO2) measurements were carried out in all flaps 72 h after flap elevation. The percentage of surviving skin area of each flap was determined by planimetry 7 days after flap elevation. The mean surviving area of the Group A (control) flaps was 71%, the mean surviving area of the Group B (H2O2-treated) flaps was 72%, the mean surviving area of the Group C (DMSO-treated) flaps was 76%, and that of the Group D (DMSO+H2O2-treated) flaps was 92%. While no statistically significant differences were found between the survival rates of both the flaps treated with H2O2 or DMSO alone and that of the control group, the mean surviving rate of the DMSO+H2O2 treated flaps (+20%) was statistically higher than that of the control flaps. Similarly, a statistically significant difference has been found between the mean PtcO2 values of the DMSO+H2O2 flaps and those of the other three groups of flaps
Autologous cutaneous grafts for experimental reconstruction of facial cartilagineous defects.
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Which is the Ideal Breast Size?: Some Social Clues for Plastic Surgeons
Full text linkTo provide plastic surgeons with more detailed information as to factors affecting the perception of female attractiveness, the present study was aimed to investigate whether the interaction effect of breast and body size on ratings of female attractiveness is moderated by sociodemographic variables and whether ratings of shapeliness diverge from those of attractiveness.A community sample of 958 Italian participants rated the attractiveness and the shapeliness of 15 stimuli (5 breast sizes × 3 body sizes) in which frontal, 3/4, and profile views of the head and torso of a faceless woman were jointly shown.Bigger breast sizes obtained the highest attractiveness ratings, but the breast-by-body size interaction was also significant. Evidence was found of a moderator role of sex, marital status, and age. When the effects of breast and body size and their interaction had been ruled out, sex differences were at best very slight and limited to very specific combinations of breast and body sizes. Ratings of attractiveness and shapeliness were highly correlated and did not significantly differ.Results suggest that to address women's psychological needs, concerns, and expectations about their appearance, plastic surgeons should not simply focus on breast size but should carefully consider the 'big picture': the body in its entirety
Computer planning for breast reconstruction by tissue expansion: an update
No full textThe use of the computer as an aid in surgery has gained increasing popularity during the past 10 years. In the field of plastic and reconstructive surgery, computer-based preoperative planning has proved useful for a variety of procedures, ranging from rhinoplasty to reconstruction of posttraumatic or congenital deformities.
In this article, we present and analyze a computer program aimed at helping the surgeon select the proper tissue expander in planning breast reconstruction. The computer program was developed to calculate the volume of the final implant needed to match the contralateral breast.
In our opinion, although this software is not aimed at replacing clinical judgment based on experience and careful observation, it is a simple and useful adjunct for the inexperienced surgeon planning to perform tissue expansion for soft-tissue reconstructions. However, it has to be stressed that, in clinical practice, several variables may decrease the effectiveness of the expansion process, thus requiring some adjustments to the preoperative evaluations
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