1,721,084 research outputs found
Pattern formation and transition to chaos in a chemotaxis model of acute inflammation
Full text linkWe investigate a reaction-diffusion-chemotaxis system that describes the immune response during an inflammatory attack. The model is a modification of the system proposed in Penner, Ermentrout, and Swigon [SIAM J. Appl. Dyn. Syst., 11 (2012), pp. 629-660]. We introduce a logistic term in the immune cell dynamics to reproduce the macrophages' activation, allowing us to describe the disease evolution from the early stages to the acute phase. We focus on the appearance of pattern solutions and their stability. We discover steady-state (Turing) and wave instabilities and classify the bifurcations deriving the corresponding amplitude equations. We study stationary radially symmetric solutions and show that they reproduce various inflammatory aggregates observed in the clinical practice. Moreover, the model supports oscillating-in-time spatial patterns, thus giving a theoretical explanation of the periodic appearance of inflammatory eruptions typical of recurrent erythema multiforme. A detailed numerical bifurcation analysis indicates that the inclusion of the logistic growth term is crucial for the occurrence of a sequence of bifurcations leading to spatio-temporal chaos. In the parameter space, there are large regions where the model system displays critical behavior
Numerical study of the primitive equations in the small viscosity regime
No full textIn this paper we study the flow dynamics governed by the primitive equations in the small viscosity regime. We consider an initial setup consisting on two dipolar structures interacting with a no slip boundary at the bottom of the domain. The generated boundary layer is analyzed in terms of the complex singularities of the horizontal pressure gradient and of the vorticity generated at the boundary. The presence of complex singularities is correlated with the appearance of secondary recirculation regions. Two viscosity regimes, with different qualitative properties, can be distinguished in the flow dynamics
16S-23S ribosomal spacer polymorphism in dairy propionibacteria
No full textThe 16S-23S spacer region was amplified from 67 strains of dairy propionibacteria using primers G1 and L1. All species are readily distinguishable from the different molecular weights of the amplified bands and sequence polymorphisms among the most similar groups can be enhanced by Hinf I restriction
Algebras for Tree Decomposable Graphs
Full text linkComplex problems can be sometimes solved efficiently via recursive decomposition strategies. In this line, the tree decomposition approach equips problems modelled as graphs with tree-like parsing structures. Following Milner’s flowgraph algebra, in a previous paper two of the authors introduced a strong network algebra to represent open graphs (up to isomorphism), so that homomorphic properties of open graphs can be computed via structural recursion. This paper extends this graphical-algebraic foundation to tree decomposable graphs. The correspondence is shown: (i) on the algebraic side by a loose network algebra, which relaxes the restriction reordering and scope extension axioms of the strong one; and (ii) on the graphical side by Milner’s binding bigraphs, and elementary tree decompositions. Conveniently, an interpreted loose algebra gives the evaluation complexity of each graph decomposition. As a key contribution, we apply our results to dynamic programming (DP). The initial statement of the problem is transformed into a term (this is the secondary optimisation problem of DP). Noting that when the scope extension axiom is applied to reduce the scope of the restriction, then also the complexity is reduced (or not changed), only so-called canonical terms (in the loose algebra) are considered. Then, the canonical term is evaluated obtaining a solution which is locally optimal for complexity. Finding a global optimum remains an NP-hard problem
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Pattern selection in the 2D FitzHugh–Nagumo model
Full text linkWe construct square and target patterns solutions of the FitzHugh–Nagumo reaction–diffusion system on planar bounded domains. We study the existence and stability of stationary square and super-square patterns by performing a close to equilibrium asymptotic weakly nonlinear expansion: the emergence of these patterns is shown to occur when the bifurcation takes place through a multiplicity-two eigenvalue without resonance. The system is also shown to support the formation of axisymmetric target patterns whose amplitude equation is derived close to the bifurcation threshold. We present several numerical simulations validating the theoretical results
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