152 research outputs found
LUCHEF D'ARTISTA: collezione a cura di R. Liberti e C. Arciprete, design di Salvatore Martorana
No full textLUCHEF d'Autore: Mostra a cura di Roberto Libert, Caterina Arciprete, Salvatore Martorana HOTEL ROMEO Napoli
No full textDRUDIT: web-based, easy-to-use DRugs DIscovery Tools to design or repurpose small molecules with biological activity
No full textTECNICHE DI RICOSTRUZIONE DELLA SUPERFICIE POSTERIORE DEL PADIGLIONE AURICOLARE E DELLA MASTOIDE CON LEMBI LOCALI
No full textB a c k g ro u n d. Reconstruction of the posterior auricular
surface and of the mastoid has never been given much attention
and there are no techniques described.
The authors describe two techniques for reconstruction
of these areas after cancer excision with local flaps.
M e t h o d s . 13 patients have been treated after cancer
resection with an advancement flap from the posterior auricular
surface and a bilobed flap from the mastoid.
R e s u l t s. All flaps healed uneventfully with a satisfactory
aesthetic outcome. No relevant complications have been
o b s e r v e d .
C o n c l u s i o n s. Reconstruction of the posterior auricular
surface and of the mastoid with the techniques described
allows satisfactory defect closure even in complex situations
such as cartilage or bone exposure
Development of stimulus-sensitive electrospun membranes based on novel biodegradable segmented polyurethane as triggered delivery system for doxorubicin
No full textIn this work, redox-sensitive polyurethane urea (PUU) based electrospun membranes have been exploited to
chemically tether a pH-sensitive doxorubicin derivative achieved by linking a lipoyl hydrazide to the drug via a
hydrazone linkage. First, the lipoyl-hydrazone-doxorubicin derivative labelled as LA-Hy-Doxo has been syn-
thesized and characterized. Then, the molecule has been tethered, via a thiol-disulfide exchange reaction, to the
redox-sensitive PUU (PolyCEGS) electrospun membrane. The redox-sensitive PolyCEGS PUU has been produced
by using PCL-PEG-PCL polyol and glutathione-tetramethyl ester (GSSG-OMe)4 as a chain extender. The LA-Hy-
Doxo tethered electrospun membrane has showed a dually controlled release triggered by acidic and reducing
conditions, producing a significant cytotoxic effect in human breast cancer cell lines (MCF-7) which has validated
the system for the post-surgical treatment of solid tumors to contrast recurrenc
La «Passio Sanctorum Septem Dormientium». Tratta del codice 2 della Biblioteca Comunale di Noto. [Reseña]
No full textReseña de: Salvatore MARTORANA (ed.), La «Passio Sanctorum
Septem Dormientium». Tratta del codice
2 della Biblioteca Comunale di Noto. Introduzione,
testo, traduzione e indici, Centro di Studi
sull'Antico Cristianesimo, Università di Catania,
1998,79 pp
Per il «Doligamus» di Adolfo di Vienna: le “fabulae” VIII e IX, ovvero alcune variazioni sul tema
No full textIl «Doligamus», opera latina in 342 distici elegiaci e 7 esametri leonini degli inizi del sec. XIV (1315), si inserisce pienamente nel filone di poesia misogina di origine clericale che ebbe grande diffusione durante il Medioevo. Il suo autore, Adolfo di Vienna, attinge alla tradizione degli "exempla" e del materiale favolistico per condannare, in nove "fabulae", il comportamento deplorevole delle donne, siano esse mogli infedeli o vecchie diaboliche. In questo lavoro, dopo una presentazione generale dell’autore e dell’opera, ci si sofferma sulle ultime due "fabulae" del «Doligamus», la VIII e la IX, delle quali vengono studiati e analizzati la trama, i modelli, lo stile, la lingua e, soprattutto, le diverse “variazioni sul tema” nell’ambito della produzione novellistica ed esemplare dei secc. XIII e XIV.The «Doligamus», a latin work of 342 elegiac couplets and 7 leonine hexameters of the beginnings of XIVth century (1315), is strictly inserted in the misogynous clerical poetry which had a big diffusion during the Middle Ages. His author, Adolph of Vienna, draws from the tradition of "exempla" and "fabulae" for condemning, in his nine "fabulae", the dreadful manners of women, adulterous wives or diabolic old females. This paper, after a general presentation on the author and the work, offers an analysis of the lost two "fabulae" of the «Doligamus» (fab. VIIIth and IXth), in his plot, sources, style, language and, expecially, in the several “variations on the theme” in the literary production of short stories and "exempla" between XIIIth and XIVth centuries
Efficacy of pollen extract in association with group B vitamins for pain relief in chronic prostatitis/chronic pelvic pain syndrome: A survey of urologists' knowledge about its clinical application
No full textIntroduction and aim of the study: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPSS) is a pathology of high prevalence in Italian male population, difficult to diagnose and to treat and with poor response to conventional therapy. Aim of this study was to review the evidence of the literature about the therapeutic effects of a plant product containing flower pollen extracts and group B vitamins on symptoms resolution and amelioration of CP/CPPS patients' quality of life and to investigate the knowledge among practicing urologists about the clinical application of this product. Materials and methods: A group of 38 urologists was submitted to an investigational survey of the knowledge of the clinical applications of a plant product containing flower pollen extracts and group B vitamins Results: 71% of the urologists interviewed prescribed the plant product for CBP and CP/CPPS at least one time in a month and 11% prescribed it more than 5 times; 67% had evidence of clear ameliorations in pain relief and on patient's quality of life and 47% reported that the effectiveness is comparable to NSAIDs; 39% also reported a significant effect for the improvement of the urinary symptoms of patients. No gastric or general side effects have been noticed during the administration period of this plant product. Finally, the cost of the product has always reported to be sustainable for the patients. Conclusions: From the results of this investigational survey, we can state that the plant product containing flower pollen extracts and group B vitamins is well-known and demonstrated beneficial effects on symptoms resolution and amelioration of quality of life in patients with chronic prostatitis/chronic pelvic pain syndrome
Bilateral spermatic cord en bloc ligation by laparoendoscopic single-site surgery: preliminary experience compared to conventional laparoscopy
No full textBACKGROUND:
Laparo Endoscopic Single-site Surgery (LESS) represents an evolution of minimally invasive surgery and aims to improve cosmetic outcome and reduce surgical trauma and complications associated with traditional laparoscopy. This study was performed to present our preliminary experience in bilateral spermatic cord ligation with the LESS technique and compare the results with the outcomes of conventional laparoscopic surgery.
METHODS:
Between June 2007 and May 2013, 24 patients were referred to our institute for bilateral varicocelectomy. The indications for this type of procedure were bilateral varicocele with impairment of semen parameters or chronic bilateral testicular pain. All procedures were performed via the same surgeon. The patients were divided into two groups according to the type of laparoscopic surgery. Group A included 10 patients underwent LESS technique while group B included the remaining 14 patients that underwent conventional laparoscopy.
RESULTS:
The comparison between the two techniques showed some important advantages for LESS: shorter operating time (45.4 min vs. 88.3 (P < .001), shorter hospital stay (16.6 hours vs. 51.4 hours) (P < .001), early return to the normal activity (2.3 days vs. 4.7 days) and better cosmetic outcomes. No conversions from LESS to conventional laparoscopy were necessary and blood loss was insignificant in all patients.All patients in the LESS group reported full satisfaction with the cosmetic outcome, whereas 85.7% of patients after conventional laparoscopy were fully satisfied with cosmesis.
CONCLUSIONS:
Bilateral spermatic cord ligation with LESS is an alternative to conventional laparoscopy. The procedure was successfully performed in all patients. The trans-umbilical approach offers the advantage of a better cosmetic result, shorter hospital stay and less postoperative pain
Retroperitoneoscopic single site renal biopsy surgery: right indicatioBMC Urology ns for the right technique.
No full textBacground:
Laparoendoscopic single-site surgery (LESS) has been developed in an attempt to further reduce the
morbidity and scarring associated with laparoscopic surgery. In patients in whom there are indications to perform a
laparoscopic renal biopsy, LESS surgery is a valid alternative to mini invasive surgery and is becoming more
common. We report our experience on 14 renal biopsy procedures performed in a retroperitoneal LESS.
Methods:
LESS renal biopsy was performed in 14 patients 18 to 80 years old (mean age 58.3 years) during a
36 month period. All procedures were performed by a single operator. The patient was in a standard flank position.
The procedure was performed using a 2.5 cm, single incision via a retroperitoneal access at the Petit
’
s triangle. A
5 mm biopsy forceps was used to collect the specimen under direct vision, and haemostasis was obtained with an
Argon beam probe and the application of oxidized regenerated cellulose gauze.
Results:
Biopsy was performed successfully in all cases. Mean operative time was 52.64 min, blood loss was
minimal, and the hospital stay ranged from 12 to 24 hours. None of the patients required narcotics or additional
analgesia in the postoperative period. No postoperative complications occurred.
Conclusions:
The LESS technique is safe, reliable (100% success), easy to learn, and offers subjective cosmetic
benefits to the patient. Minimal hospitalization requirement following retroperitoneal LESS biopsy is an additional
timely advantage over laparoscopic renal biopsy. We think that with the right indications (marked obesity, failure of
previous percutaneous biopsy attempts, a solitary kidney and coagulopathy) LESS renal biopsy is a good alternative
to laparoscopy. Our next step will be a randomized prospective study of LESS compared with laparoscopy for renal
biopsy to support our findings
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