3,278 research outputs found
A successful model of regional healthcare information exchange in Japan: Case Study in Kagawa Prefecture
No full textIn this study, we focused on analysis of healthcare data exchange over the network. For the advance of broadband capability development, many governments expect online medical information exchange between medical institutions. Japanese government also has tried to deploy ICT in the healthcare field. In Japan, many healthcare ICT projects started, but almost of all the projects face many issues and failed to continue. This situation caused us to clarify the success factor of healthcare information exchange network. For inspecting the success factors, we analyzed information access of healthcare systems in Kagawa prefecture of Japan. Kagawa prefecture is one of the most advance areas for healthcare information technology. We analyzed four medical ICT projects in Kagawa prefecture: K-MIX, Critical Pathway for Diabetes, E-prescription, and PHR. In addition, we inspected characteristics of exchanged data in the network, and stakeholder involved in these projects. This analysis lets us find various types of healthcare ICT projects. Characteristic of data processed in the projects caused differences of characteristic of the projects. On the other hand, multiple systems process same data, though the project does not share the data itself. Considering various types of medical information exchanges projects, we propose classification and standard format of exchanged data according to their characteristic are critical for efficient business deployment. --e-Health,regional healthcare information exchange,EHR
A method to identify pulmonary intersegmental planes with intravenous vitamin B2 injection
No full text博士論文 要旨Abstract/本文Full 以下に掲載：Surgery Today 51(5) pp.836-843 2021. Japan Surgical Society. 共著者：Daisuke Saito, Isao Matsumoto, Ryuichi Waseda, Keisuke Tatemichi, Yusuke Tanaka, Shuhei Yoshida, Munehisa Takata, Masaya Tamura, Hirofumi Takemur
The roles of the medial prefrontal cortex and striatum in reputation processing
No full textHow we are viewed by other individuals-our reputation-has a considerable influence on our everyday behaviors and is considered an important concept in explaining altruism, a uniquely human trait. Previously it has been proposed that processing one's own reputation requires a reputation representation in the medial prefrontal cortex (mPFC) and a value representation in the striatum. Here, we directly tested this idea using functional magnetic resonance imaging (fMRI). Subjects disclosed their behavioral tendencies with reference to social norms in the presence or absence of other people, a manipulation that is known to greatly affect an individual's concern for their reputation. The mPFC showed strong activation during self-referential processing, and this activity was enhanced by the mere presence of observers. Moreover, the striatum was also strongly activated when subjects responded in front of observers. Thus, the present study demonstrated that the mPFC and striatum were automatically recruited when the task placed a high demand on processing how one is viewed by others. Taken together, our findings suggest that the mPFC and the striatum play a key role in regulating human social behaviors, and these results provide valuable insight into the neural basis of human altruism
Processing of the incentive for social approval in the ventral striatum during charitable donation
No full textHuman behaviors are motivated not only by materialistic rewards but also by abstract social rewards, such as the approval of others. When choosing an action in social situations, to evaluate each action, the brain must convert different types of reward (such as money or social approval) into a common scale. Here using fMRI, we investigated the neural correlates of such valuation computations while individuals freely decided whether to donate to real charities or to take the money for themselves in the presence or absence of observers. Behavioral evidence showed that the mere presence of observers increased donation rates, and neuroimaging results revealed that activation in the ventral striatum before the same choice ("donate" or "not donate") was significantly modulated by the presence of observers. Particularly high striatal activations were observed when a high social reward was expected (donation in public) and when there was the potential for monetary gain without social cost (no donation in the absence of observers). These findings highlight the importance of this area in representing both social and monetary rewards as a "decision utility" and add to the understanding of how the brain makes a choice using a "common neural currency" in social situations
Processing of Social and Monetary Rewards in the Human Striatum
No full textSummaryDespite an increasing focus on the neural basis of human decision making in neuroscience, relatively little attention has been paid to decision making in social settings. Moreover, although human social decision making has been explored in a social psychology context, few neural explanations for the observed findings have been considered. To bridge this gap and improve models of human social decision making, we investigated whether acquiring a good reputation, which is an important incentive in human social behaviors, activates the same reward circuitry as monetary rewards. In total, 19 subjects participated in functional magnetic resonance imaging (fMRI) experiments involving monetary and social rewards. The acquisition of one's good reputation robustly activated reward-related brain areas, notably the striatum, and these overlapped with the areas activated by monetary rewards. Our findings support the idea of a “common neural currency” for rewards and represent an important first step toward a neural explanation for complex human social behaviors
sj-xlsx-4-tct-10.1177_15330338221138217 - Supplemental material for Establishment of Rapid and Accurate Screening System for Molecular Target Therapy of Osteosarcoma
No full textSupplemental material, sj-xlsx-4-tct-10.1177_15330338221138217 for Establishment of Rapid and Accurate Screening System for Molecular Target Therapy of Osteosarcoma by Keita Sasa, Tsuyoshi Saito, Taisei Kurihara, Nobuhiko Hasegawa, Kei Sano, Daisuke Kubota, Keisuke Akaike, Taketo Okubo, Takuo Hayashi, Tatsuya Takagi, Muneaki Ishijima and Yoshiyuki Suehara in Technology in Cancer Research & Treatment</p
sj-docx-1-tct-10.1177_15330338221138217 - Supplemental material for Establishment of Rapid and Accurate Screening System for Molecular Target Therapy of Osteosarcoma
No full textSupplemental material, sj-docx-1-tct-10.1177_15330338221138217 for Establishment of Rapid and Accurate Screening System for Molecular Target Therapy of Osteosarcoma by Keita Sasa, Tsuyoshi Saito, Taisei Kurihara, Nobuhiko Hasegawa, Kei Sano, Daisuke Kubota, Keisuke Akaike, Taketo Okubo, Takuo Hayashi, Tatsuya Takagi, Muneaki Ishijima and Yoshiyuki Suehara in Technology in Cancer Research & Treatment</p
Supplemental Material, Supplemental_figure_1 - The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study
No full textSupplemental Material, Supplemental_figure_1 for The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study by Daisuke Kudo, Mineji Hayakawa, Hiroaki Iijima, Kazuma Yamakawa, Shinjiro Saito, Shigehiko Uchino, Yusuke Iizuka, Masamitsu Sanui, Kohei Takimoto, Toshihiko Mayumi, and JSEPTIC DIC Study Investigators in Clinical and Applied Thrombosis/Hemostasis</p
Supplemental Material, Appendix1_Ethics_committee_071618 - The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study
No full textSupplemental Material, Appendix1_Ethics_committee_071618 for The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study by Daisuke Kudo, Mineji Hayakawa, Hiroaki Iijima, Kazuma Yamakawa, Shinjiro Saito, Shigehiko Uchino, Yusuke Iizuka, Masamitsu Sanui, Kohei Takimoto, Toshihiko Mayumi, and JSEPTIC DIC Study Investigators in Clinical and Applied Thrombosis/Hemostasis</p
Supplemental Material, Suppl_figure_2_021519_(1) - The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study
No full textSupplemental Material, Suppl_figure_2_021519_(1) for The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study by Daisuke Kudo, Mineji Hayakawa, Hiroaki Iijima, Kazuma Yamakawa, Shinjiro Saito, Shigehiko Uchino, Yusuke Iizuka, Masamitsu Sanui, Kohei Takimoto, Toshihiko Mayumi, and JSEPTIC DIC Study Investigators in Clinical and Applied Thrombosis/Hemostasis</p
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