1,060 research outputs found
La estrella de Lima convertida en sol sobre sus tres coronas, el b. Toribio Alfonso Mogrobexo, su segundo arzobispo : celebrado con epitalamios sacros y solemnes cultos, por su esposa la Santa Iglesia Metropolitana de Lima, al activo y soberano influxo del exmo. e illmo. señor doct. d. Melchor de Liñan y Cisneros ... : descripcion sacro politica de las grandezas de la ciudad de Lima, y compendio historico eclesiastico de su Santa Iglesia Metropolitana /
No full textAdded title, port. of Toribio, and folded plan of Lima, all engraved by Joseph Mulder.Signatures: *-2*⁴ 3*² A-3B⁴ 3C⁴(3C4+chi).Mode of access: Internet.Ownership inscription on t.p. of the Convento di S. Carlo alle Quattro Fontane, Rome.Binding: limp vellum, two pairs of ties at fore edge, title & author written on spine
Behavioral modeling of GaN-based power amplifiers: impact of electrothermal feedback on the model accuracy and identification
No full textIn this article, we discuss the accuracy of behavioral models in simulating the intermodulation distortion (IMD) of microwave GaN-based high-power amplifiers in the presence of strong electrothermal (ET) feedback. Exploiting an accurate self-consistent ET model derived from measurements and thermal finite-element method simulations, we show that behavioral models are able to yield accurate results, provided that the model identification is carried out with signals with wide bandwidth and large dynamics
The rs4846049 polymorphism in the 3’UTR region of the MTHFR gene increases the migraine susceptibility in an Iranian population
No full textMohaddeseh Salehi,1,* Mona Amin-Beidokhti,2,* Behnam Safarpour Lima,3 Milad Gholami,2 Gholam-Reza Javadi,1 Reza Mirfakhraie2,4 1Department of Biology, Islamic Azad University, Science and Research Branch, 2Department of Medical Genetics, 3Department of Neurology, School of Medicine, 4Genomic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran *These authors contributed equally to this work Introduction: Migraine is a painful complex neurovascular disease characterized by recurrent moderate-to-severe headaches. Increased level of homocysteine is related to dilation of cerebral vessels and endothelial injury that could trigger migraine attacks. Functional polymorphisms in the MTHFR gene affect homocysteine metabolism and, therefore, play an important role in the etiology of the disease. Objectives: We aimed to investigate the possible association between MTHFR gene rs4846049, C677T, and A1298C polymorphisms and the risk of migraine in Iranian population. Methods: In this genetic association study, 498 individuals were enrolled, including 223 migraine patients and 275 healthy controls. Genotyping was performed using tetra-primer ARMS-PCR for rs4846049 and PCR-restriction fragment length polymorphism for C677T and A1298C polymorphisms. Results: The association between rs4846049 and C677T polymorphisms and migraine was observed. For the rs4846049 polymorphism, the association was detected under a dominant model (P=0.007; odds ratio [OR] =0.60; 95% confidence interval [CI], 0.41–0.87), and for the C677T polymorphism, the TT genotype frequency was significantly different in the studied groups (P=0.009; OR =2.48; 95% CI, 1.25–4.92). No significant differences in the genotype or allele frequencies were found for the A1298C polymorphism between the migraineurs and controls. Conclusion: Present data provide evidence for the association of rs4846049 and C677T polymorphisms in the MTHFR gene and migraine. Further studies are required to validate the significance of the studied genetic variations in diverse ethnic populations. Keywords: migraine, genetic association study, MTHFR, single nucleotide polymorphis
Looking for alternatives in the city of the slopes: Housing as a process to reduce socio-spatial segregation in Lima, Peru
No full textLike many other Latin American cities, Lima experienced explosive population growth during the last century. Its population went from 600 thousand people in 1940 to nearly 9.5 million people nowadays. Former agriculture fields between the coast and the beginning of the Andes mountains were quickly filled with urban developments. Neither the public sector nor the private housing market provided decent living conditions in the city for all these newcomers. 34% of the city’s land was developed informally (Municipality of Lima, 2013a) and 70% of the houses were to some degree self-built. The process of urban development and, specifically, the control of the space through land ownership, generated a segregated city. The urban poor usually accessed low-cost land or housing in areas exposed to high levels of risk, with accessibility problems or lack of basic infrastructure.The current process of urban development, along with a quantitative understanding of housing in policy, continues reproducing socio-spatial segregation today. Buying a plot to land traffickers on the steep slopes of the periphery is the primary way for the low-income population to access a place to live in the city.This graduation project has two main goals. On the one hand, it tries to understand the relations between housing, urban development and socio-spatial segregation in Lima. On the other, it explores the potential of housing (understood as a process) to develop alternative models of urban development and reduce socio-spatial segregation, in search of a more just city.European Master in Urbanism (EMU)European Master in Urbanism (EMU
O A.B.C. de Lima Barreto (1916-1922)
No full textEsta dissertação tem por objetivos: levantamento, indexação e análise dos textos publicados pelo escritor Afonso Henriques de Lima Barreto (1881-1922) no periódico carioca A.B.C. (1915-1934), que foram veiculados de 1916 a 1922, com ênfase na série de capítulos da sátira Os Bruzundangas; e a investigação do hebdomadário visando ao esboço de um perfil para a publicação. A análise dos textos foi feita em seu conjunto, o que, até hoje, a fortuna crítica do autor não havia realizado, tentando notar possíveis condicionamentos do veículo sobre sua produção. A dissertação contém, em anexo, texto de Lima Barreto inédito em livro, cotejo crítico dos capítulos d’Os Bruzundangas publicados no A.B.C., indexação do semanário no período de publicação da sátira e ilustrações. Com tudo isso, o estudo pretende contribuir para uma maior compreensão da obra de Lima Barreto e auxiliar futuros pesquisadores do autor e do tema em questãoThis dissertation intends to gather, index and analyze texts published by author Afonso Henriques de Lima Barreto (1881-1922) on the periodical A. B. C. (1915-1934) between 1916 and 1922, with emphasis the series of chapters of the satire Os Bruzundangas; we also investigate the weekly publication in order to paint an accurate picture of it. The analysis of these texts in as a whole has not been done until now, and was made with the intention of possibly noting the influence of the medium on its production. Annexed to the dissertation we have Lima Barreto's writings that were not yet edited, a critical comparison between the chapters of Os Bruzundangas published in A.B.C. and an index of the periodical during the production of satires and illustrations. We intend to provide a better understanding of Lima Barreto's work, as well as make resources available to future researchers of the author and the themeFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
O A.B.C. de Lima Barreto (1916-1922)
No full textEsta dissertação tem por objetivos: levantamento, indexação e análise dos textos publicados pelo escritor Afonso Henriques de Lima Barreto (1881-1922) no periódico carioca A.B.C. (1915-1934), que foram veiculados de 1916 a 1922, com ênfase na série de capítulos da sátira Os Bruzundangas; e a investigação do hebdomadário visando ao esboço de um perfil para a publicação. A análise dos textos foi feita em seu conjunto, o que, até hoje, a fortuna crítica do autor não havia realizado, tentando notar possíveis condicionamentos do veículo sobre sua produção. A dissertação contém, em anexo, texto de Lima Barreto inédito em livro, cotejo crítico dos capítulos d’Os Bruzundangas publicados no A.B.C., indexação do semanário no período de publicação da sátira e ilustrações. Com tudo isso, o estudo pretende contribuir para uma maior compreensão da obra de Lima Barreto e auxiliar futuros pesquisadores do autor e do tema em questãoThis dissertation intends to gather, index and analyze texts published by author Afonso Henriques de Lima Barreto (1881-1922) on the periodical A. B. C. (1915-1934) between 1916 and 1922, with emphasis the series of chapters of the satire Os Bruzundangas; we also investigate the weekly publication in order to paint an accurate picture of it. The analysis of these texts in as a whole has not been done until now, and was made with the intention of possibly noting the influence of the medium on its production. Annexed to the dissertation we have Lima Barreto's writings that were not yet edited, a critical comparison between the chapters of Os Bruzundangas published in A.B.C. and an index of the periodical during the production of satires and illustrations. We intend to provide a better understanding of Lima Barreto's work, as well as make resources available to future researchers of the author and the themeFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
Modernismo negro: amefricanidade, oralitura e continnum em Lima Barreto
No full textThis text invests in the discussion about the existence, constitution and characterization of a
black modernism, in Brazilian literature, triggered from the work of Lima Barreto. At first,
after a brief discussion on the central discursive formations of São Paulo modernism, we
investigated the tensions, continuities and ruptures that mark the relations between the Rio de
Janeiro author and the group of the week of 22. In this framework, central categories in the
constitution of the field national literary texts such as: between-place, rupture and critical
assimilation are considered inappropriate, as an exclusive critical apparatus, to
instrumentalize the understanding of the specificities of Barretian work, which, in turn, brings
into play an epistemic and political repertoire linked to the black cultural tradition in Brazil,
until then neglected by the traditional field of Brazilian criticism. With this movement, Lima
Barreto's work requires, for his exegesis, a new set of theoretical and critical devices that
challenged and challenged the literary field. In the sequence, we seek to demonstrate how the
attributes of the Barretian work are marked by black-Brazilian culture. We used three notions
as the basis for this argument: language, territory and memory. From these discursive nuclei
we endeavor to present two central aspects of the Barretian work: a) how the work of the
black novelist dialogues intensively with the Afro-Brazilian cultural repertoire, resulting from
the processes of reterritorialization of African culture in Brazil; b) the fact that his work
constitutes a powerful critical contribution to the modern project, above all, the way it was
developed in Brazil, through the duplication of the colonial structure in the modernizing
movements of Brazilian society. In the third movement of this text, we seek to speculate on
the contributions of Lima Barreto's work to contemporary Brazilian society, starting from
three nuclei: the constitution of an ethics, its contribution to the work of the black intellectual,
and its importance in the constitution of a criticism literature that is less Eurocentric and more
open to dialogues with the multiple epistemic inscriptions of Brazilian culture. As a starting
point for this research, we established Lima Barreto's novels as a corpus, and undertook a
bibliographic survey of his works and Brazilian modernism. In establishing the theoretical
framework, we resort to dialogue with a field that has been solidifying in Brazilian criticism
and which is characterized by the production of a critical and analytical repertoire produced
from black culture in Brazil, therefore, consistent with the central objective of this study, or
that is, to analyze the work of Lima Barreto from a non-Eurocentric theoretical framework,
thinking and pushing the limits of the critical field of Brazilian letters. For this purpose, we
dialogue more intensely with the works of Muniz Sodré (2002), (2017), Leda Maria Martins
(1997), Lélia Gonzáles (1988) and Beatriz Nascimento (2007), José Henrique Freitas (2016),
Edmilson de Almeida Pereira ( 2010), (2017)Esse texto investe na discussão acerca da existência, constituição e caracterização de um
modernismo negro, na literatura brasileira, desencadeado a partir da obra de Lima Barreto.
Em um primeiro momento, após uma breve discussão sobre as formações discursivas centrais
do modernismo paulista, investigamos as tensões, continuidades e rupturas que marcam as
relações entre o autor carioca e o grupo da semana de 22. Nesse quadro, categorias centrais na
constituição do campo literário nacional como: entre-lugar, ruptura e assimilação crítica são
entendidas inapropriadas, como aparato crítico exclusivo, para instrumentalizar a
compreensão das especificidades da obra barreteana, que, por sua vez, põe em cena um
repertório epistêmico e político vinculado a tradição cultural negra no Brasil, até então
negligenciado pelo campo tradicional da crítica brasileira. Com esse movimento a obra de
Lima Barreto exige, para sua exegese, um conjunto novo de dispositivos teórico-críticos que
desafiavam e desafiam o campo literário. Na sequencia buscamos demonstrar como os
atributos da obra barreteana são marcados pela cultura negro-brasileira. Utilizamos três
noções como base desse argumento: língua, território e memória. A partir desses núcleos
discursivos nos esforçamos em apresentar dois aspectos centrais da obra barreteana: a) como a
obra do romancista negro dialoga intensivamente com o repertório cultural afro-brasileiro,
resultante dos processos de reterritorialização da cultura africana no Brasil; b) o fato de sua
obra se constituir em um potente aporte crítico ao projeto moderno, sobretudo, do modo como
ele foi desenvolvido no Brasil, por meio da duplicação da estrutura colonial nos movimentos
modernizadores da sociedade brasileira. No terceiro movimento desse texto, buscamos
especular sobre as contribuições da obra de Lima Barreto para a sociedade brasileira
contemporânea, partindo de três núcleos: a constituição de uma ética, sua contribuição para o
trabalho do intelectual negro, e sua importância na constituição de uma crítica da literatura
que seja menos eurocêntrica e mais aberta aos diálogos com as múltiplas inscrições
epistêmicas da cultura brasileira. Como ponto de partida dessa pesquisa, estabelecemos como
corpus os romances de Lima Barreto, e empreendemos um levantamento bibliográfico sobre
suas obras e sobre o modernismo brasileiro. No estabelecimento do referencial teórico
recorremos ao diálogo com um campo que vem se solidificando na crítica brasileira e que se
caracteriza pela produção de um repertório crítico e analítico produzido a partir da cultura
negra no Brasil, portanto, condizente com o objetivo central deste estudo, ou seja, analisar a
obra de Lima Barreto a partir de um referencial teórico não-eurocentrico, pensando e
esgarçando os limites do campo crítico das letras brasileiras. Para tanto dialogamos mais
intensamente com os trabalhos de Muniz Sodré (2002), (2017), Leda Maria Martins (1997),
Lélia Gonzáles (1988) e Beatriz Nascimento (2007), José Henrique Freitas (2016), Edmilson
de Almeida Pereira (2010), (2017)
Monumentos públicos y espacios urbanos. Lima, 1919-1930
No full text[spa] El objeto de este trabajo es el arte público de Lima y su relación con los procesos de "hacer ciudad" durante el periodo 1919-1930. En este trabajo la autora identifica el gobierno de Augusto B. Leguía (1919 - 1930) como un momento clave dentro de la historia republicana en que se dio un proyecto racional, armónico y funcional para el desarrollo de la ciudad de Lima Metropolitana. Una primera parte de antecedentes se remontan a la demolición de las murallas de Lima, abarcando las propuestas de modernización de la ciudad hasta el inicio de 1919. La propuesta de la "Patria Nueva", el discurso político y económico del gobierno del Oncenio, es el sustento clave de la concepción de un proyecto urbano y de producción artística-escultórica y paisajística, concentrada, mayormente, en el estilo Neo-Peruano. La autora incluye un registro pormenorizado de todos los monumentos en espacios públicos de la época, analizando tendencias, estilos, y contextos en la ciudad y su entorno, así como una tipología de parques, plazas, alamedas, avenidas y demás espacios públicos. La pertinencia de la investigación va mas allá de cubrir vacíos en la investigación del tema y exponer logros y contradicciones del proyecto urbanístico y de ornato, planteando interrogantes acerca del futuro urbano de Lima.[eng] The subject of this dissertation is Lima's public art and its relationship with the processes of "city making", during the period 1919-1930. In this dissertation, the author identifies the government of Augusto B. Leguía (1919 - 1930), called also the Oncenio, as a key moment in the republican history of Peru, when there was a rational, harmonious and functional proposal of development of the city of Lima. Starting in 1866, when the city walls were demolished, the author analyzes successive modernizing urban proposals up to 1919. The political and economic ideas that support the scheme of the "Patria Nueva" are the basis of an urban design and production of artistic and sculptural landscape, concentrated mostly in the style called "Neo-Peruvian". The author includes a detailed record of spaces and monuments, parks, plazas, malls, streets, built in the Oncenio in public spaces, analyzing trends, styles, and contexts in the city and its surroundings. The relevance of the research goes beyond the covering historic research gaps, in its search of the achievements and contradictions of this project, in order to raise questions about the urban future of Lima
Genetic diversity of the mitochondrial cytochrome b gene in Lutzomyia spp., with special reference to Lutzomyia peruensis, a main vector of Leishmania (Viannia) peruviana in the Peruvian Andes
No full textThe genetic divergence caused by genetic drift and/or selection is suggested to affect the vectorial capacity and insecticide susceptibility of sand flies, as well as other arthropods. In the present study, cytochrome b (cyt b) gene sequences were determined in 13 species circulating in Peru to establish a basis for analysis of the genetic structure, and the intraspecific genetic diversity was assessed in the Lutzomyia (Lu.) peruensis, a main vector species of Leishmania (Viannia) peruviana in Peruvian Andes. Analysis of intraspecific genetic diversity in the cyt b gene sequences from 36 Lu. peruensis identified 3 highly polymorphic sites in the middle region of the gene. Haplotype and gene network analyses were performed on the cyt b gene sequences of 130 Lu. peruensis in 9 Andean areas from 3 Departments (Ancash, Lima and La Libertad). The results showed that the populations of La Libertad were highly polymorphic and that their haplotypes were distinct from those of Ancash and Lima, where dominant haplotypes were observed, suggesting that a population bottleneck may have occurred in Ancash and Lima, but not in La Libertad. The present study indicated that the middle region of the cyt b gene is useful for the analysis of genetic structure in sand fly populations
Axisymmetric polydimethysiloxane microchannels for in vitro hemodynamic studies
No full textThe current microdevices used for biomedical research are often manufactured using microelectromechanical systems (MEMS) technology. Although it is possible to fabricate precise and reproducible rectangular microchannels using soft lithography techniques, this kind of geometry may not reflect the actual physiology of the microcirculation. Here, we present a simple method to fabricate circular polydimethysiloxane (PDMS) microchannels aiming to mimic an in vivo microvascular environment and suitable for state-of-the-art microscale flow visualization techniques, such as confocal µPIV/PTV. By using a confocal µPTV system individual red blood cells (RBCs) were successfully tracked trough a 75 µm circular PDMS microchannel. The results show that RBC lateral dispersion increases with the volume fraction of RBCs in the solution, i.e. with the hematocrit
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