163,805 research outputs found

    La formula ‘utei quoi optuma lege’ nella l. 27 della lex agraria del 111 a.C.: elementi per una rilettura politica e giuridico-costituzionale

    No full text
    The essay discusses the thesis of a possible political and juridical-constitutional meaning of the formula ut qui optima lege present in l. 27 of the epigraphic agrarian law of 111 BC The legislator may have used this formula not to distinguish a category of land ownership free from public or private charges of any kind, but to sanction the will and legitimacy of the legislator to confer full dominical title by law to the holders of the assigned ager privatus, with magistrates with adequate power. A dominical affiliation conferred therefore outside the traditional rules of the quiritary domain (hereditas, mancipatio, in iure cessio, etc.), but legitimate from the point of view of the ius publicum. A ‘plenissimum ius’ conferred ope legis or ‘by virtue of the maximum powers conferred by the law’ (l. 27: utei quoi optuma lege privatus est, esto)

    Identification of delayed potassium and calcium currents in the rat sympathetic neurone under voltage clamp

    No full text
    Post-ganglionic neurones of the isolated rat superior cervical ganglion were studied at 37 degrees C under two-electrode voltage-clamp conditions. Membrane depolarization beyond -40 mV from holding levels between -50 and -100 mV produced a delayed outward current which exhibited no inactivation within this voltage range. The current is carried primarily by K+ ions and its instantaneous I-V relation is linear. The total outward current could be separated into two distinct components on the basis of ion-substitution experiments. A voltage-dependent component of the delayed current, termed IK(V), is activated by membrane depolarization beyond -40 mV when Ca2+ fluxes are selectively blocked by Cd2+ or in Ca2+-free solution. IK(V) develops following first-order kinetics and rises to a peak with a voltage-dependent delay (239 ms at -30 mV and 23 ms at +10 mV). GK(V) attains a saturating value of the order of 17 mS/cm2 at about +20 mV and can be described in terms of a simple Boltzmann distribution for a single gating particle with a valency equal to +2.5. A second component of the delayed outward current, termed IK(Ca), depends on Ca2+ entry for its activation and was isolated as difference current before and after block of Ca2+ movements across the membrane. IK(Ca) is larger and faster than IK(V): it is strictly related to Ca2+ influx and also depends on membrane potential depolarization. A distinct Ca2+ current, ICa, was recorded from the neurone exposed to Na+-free or tetrodotoxin solution. ICa was activated by membrane depolarization beyond -30 mV and reached a maximum value near 0 mV. Its activation agrees with fourth-order kinetics and becomes faster with increasing depolarization. The Ca2+ current developed with a voltage-dependent time to peak of 2.9-1.8 ms and thereafter completely inactivated. The relationship between ICa and IK(Ca) is discussed. The Ca2+-k+ repolarizing system is expected to be mainly associated with action potentials arising from a depolarized neurone, whereas the IA current (Belluzzi, Sacchi & Wanke, 1985) dominates the repolarization mechanism at the normal membrane potential. The effect of muscarine was examined. Muscarine (10-50 microM) produced a fall in conductance with a voltage dependence similar to that exhibited by GK(Ca) and was ineffective when removing extracellular Ca2+ or adding Cd2+. A partial suppression of ICa by muscarine is demonstrated. It is suggested that the decrease of the outward current magnitude in the presence of muscarine may be accounted for qualitatively by the reduction in ICa

    Libertà e libero arbitrio alla sfida degli algoritmi e del mondo globalizzato

    No full text
    Brevi considerazioni sul rapporto tra mente/cervello, tra libertà e globalizzazione, tra libertà e legge, e sul ruolo della coscienza anche in un mondo governato da algoritmi

    Prof. Domenico Sacchi

    No full text
    Botanico: Sacchi, Domenico. Titolo sul recto, dove compare anche la scritta: Daniele. 1 incisione : litografia ; 137 x 147 mm. Vai alla scheda bibliografica: https://galileodiscovery.unipd.it/discovery/fulldisplay?context=L&vid=39UPD_INST:VU1&search_scope=MyInst_and_CI&tab=Everything&docid=alma99001598418020604

    L’ager privatus della lex del 111 a.C. come proprietà fondiaria nella prospettiva giuridica del suo tempo

    No full text
    Il complesso assetto normativo e disciplinatorio dell’ager privatus della legge agraria epigrafica fu una tappa fondamentale per l’evoluzione storico-giuridica della proprietà in genere e fondiaria in particolare. Uscita dall’ambito esclusivo del diritto familiare e quindi privato, questa cominciò a essere configurata in diritto romano grazie all’effetto sinergico di tre fattori: la legge, l’editto del pretore e l’attività negoziale (locazioni censorie e vendite questorie) anche come una questione di rilevanza pubblica; e di questo la legge del 111 a.C. reca ampia testimonianza. Dopo una rassegna delle varie figure previste dalla legge (ager privatus optima lege, ager privatus vectigalisque, ager publicus datus adsignatus), nel saggio si esamina la figura dell’ager privatus che appare in età repubblicana una proprietà fondiaria articolata come pluralità di statuti proprietari di cui, per ragioni storiche, l’elemento strutturale era la possessio, ossia il meum esse aio, una figura conosciuta dal diritto romano processuale sin da età più risalente. La persistenza nelle fonti repubblicane dell’opposizione mancipium/ius fino a Orazio (epist. 2.2,158-162), adeguata alla cultura giuridica del tempo, mostra una configurazione dell’ager privatus come species di in bonis habere ex lege (inquadrabile nelle res humani iuris che singulorum hominum sunt) presentandone tutti i requisiti
    corecore