139 research outputs found
Interview with Professor Mark Brodin about his book William P. Homans Jr.: A Life In Court
No full textBoston lawyer William P. Homans Jr. devoted his fifty-year career to the defense of the poor and downtrodden, the protection of our most basic civil liberties, and the abolition of the death penalty. Descendant of two of Boston\u27s oldest and most prominent families, and combat veteran of both the British and American Navies during World War II, Homans became unlikely guru to the 1960s generation of radical lawyers and antiwar activists. He was on the defense team in the 1968 conspiracy trial of Dr. Benjamin Spock and four other leading opponents of the Vietnam War accused of aiding and abetting resistance to the military draft, and represented Dr. Kenneth Edelin in the 1975 manslaughter prosecution arising out of a lawful abortion performed after Roe v. Wade. The narrative contrasts Bill Homans\u27 storied legal career with a troubled personal life in a balanced but unvarnished manner, testifying to the strength of the human spirit when committed to the pursuit of the common good. About the author: Mark S. Brodin is Professor of Law at Boston College Law School and the author of numerous books and law journal articles in the areas of civil and criminal procedure, evidence, litigation, and employment discrimination. A graduate of Columbia College (1969) and Columbia Law School (1972), he served as law clerk to United States District Judge Joseph L. Tauro and staff attorney with the Lawyers\u27 Committee for Civil Rights in Boston. He has also practiced for brief periods as a public defender in Boston and a prosecutor in Norfolk County
Chapter 3 3D Structure 2. Three Dimensional Structure of Oligosaccharides Explored by NMR and Computer Calculations
No full text
Culture complex, Westerpark, Amsterdam
No full textA design method of combining bottom-up and top-down ideas, realizing a culture complex building.Architectural EngineeringArchitectureArchitecture and The Built Environmen
Reclaimed Houses
No full textArchitecture and The Built EnvironmentArchitectural Engineering +Technolog
Residual dipolar couplings as new conformational restraints in isotopically 13C-enriched oligosaccharides
No full textAbstractWe report the measurement of residual dipolar couplings for 13C-enriched NeuNAcα2-3Galβ1-4Glc in a dilute liquid-crystalline medium. These couplings provide long-range conformational restraints that hitherto have not been available for oligosaccharides. We utilise these restraints in dynamical simulated annealing calculations, which support current models of the solution behaviour of the trisaccharide
Structure and dynamics in oligomannose-type oligosaccharides. Biochemistry
No full textABSTRACT: Using a combination of 'H N M R nuclear Overhauser effect measurements, molecular orbital calculations, and molecular dynamics simulations, we have determined the tertiary structure and dynamic properties of the oligomannose oligosaccharide Mana6(Mana3)Mana6(Mana3)Manp4GlcNAc~4GlcNAc. While the calculated potential surfaces for the majority of the glycosidic linkages could be described by a single deep potential well, similar calculations for the M a n a l d M a n a and Mana 1-6Manp linkages described a diffuse, shallow well, suggesting that a larger degree of flexibility exists about the latter. These conclusions are supported by the results of molecular dynamics simulations, which suggest that the N M R data should be interpreted in terms of a degree of flexibility about the M a n a l d M a n p and Manal-6Mana linkages. In contrast, a similar series of investigations suggests that the conformation of the M a n a l d M a n B linkage in Mana2Man6(Mana2Man~3)Mana6(Mana2Mana2Mana3)Man~4GlcNAc~4GlcNAc is more restricted, resulting in an overall structure that is "restrained". High-resolution *H nuclear magnetic resonance is a well-established method for the derivation of the three-dimensional structures of biomolecules in solution. The use of two-di-mensional coherence-transfer methods such as 'H-lH corre
A sustainable seaweed farm for sustainable food production in the Netherlands
No full textArchitectural Engineering and TechnologyArchitecture and The Built Environmen
Efficiency - Facade PLUS - to form an urban Benchmark
No full textIntension In this graduation project I will make a redevelopment of the Q-Port building to a Hotel and Congress Centre: On the one hand, my project focuses on the refurbishment of an office façade into an energy producing façade. This renew has an ecological, social and economic importance. These three aspects reflect my sustainable approach. On the other hand, the establishment of a new use strategy for the Q-Port building in form of a Hotel and Congress Centre plays a key role. The Q-Port building is a bad example of urban planning when an important aspect of life – work – leads to mono-functional urban sectors. Instead of thinking in certain functional categories, I want to create spaces in the urban context in which we simply enjoy living – spaces with leeway for individuality – regardless of how large the building is. KEY Feature - “Grüne Lunge” Key feature of my design is the “Grüne Lunge”, an open public way and an energy generating technology as design element of the façade to unite the urban concept and the energy concept within the façade design. The redesign of the Q-Port building is linked to the historic urban planning strategy to be a green recreational area. Urban porosity is the key intention of the new hybrid Q-Port building with the aim of pedestrian oriented urban places. The transformed Q-Port building becomes localized a `social condenser´ for new communities: The “Grüne Lunge”, an open public space spirals upwards from the street and guides the people through the building. ReDesign The redesign is not only use related but also energy efficient with the design of an energy generating façade, which makes the building to an energy production. In the focus there is an active intelligent façade, the “Grüne Lunge”, in relation to the climate of a building and the possibility for the urban context: The façade is my fascination because it shows most dominant the architectural value of a building. It is the visible statement to the world and it gives a face to the building. Façades connect the inside space and the outside city rooms and have a high potential as multifunctional construction elements. The new task of the façade in my design is, that the “Grüne Lunge”, which is an open public way, is linked to the energy concept of the whole building and is main part of the ventilation concept. The “Grüne Lunge” is an open public way, which spirals upwards, and guaranties natural ventilation in the rooms. In the summer time it transports cold air from the north side of the building into the south part. The night cooling out of the building in the summer is done by the “Grüne Lunge”. In the winter time the air is transported from the south side of the building and is preheated in the buffer zone of the “Grüne Lunge” and flows over an air guide system in the suspended floors into the rooms. Moreover, the “Grüne Lunge” acts as an interspace and a connection point for the public and private activities within the building. Benchmark The perforated glass in the building envelope is only broken by the transparent envelope of the “Grüne Lunge”. The “Grüne Lunge” in the building`s envelope can be seen from the highway or the streets and by this people get interested in the new use strategy of the Q Port building. The new Q Port building should become a highlight building in the Brettenzone like a Benchmark for the city part Brettenzone. Therefore the installation of a media façade which offers surface for commercial activities is done in addition to the BIPV modules at the closed façade parts. This is the next step into a more sustainable future: The energy concept for the Q-Port building is able to generate energy within the façade and so unifies the energy demands of the future.Architectural Engineering and TechnologyArchitecture and The Built Environmen
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