606 research outputs found

    Goffredo Venuta, Liberio arbitrio e Lïberta della grazia nel pensiero di s. Bernardo, 1953

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    Nédoncelle Maurice. Goffredo Venuta, Liberio arbitrio e Lïberta della grazia nel pensiero di s. Bernardo, 1953. In: Revue des Sciences Religieuses, tome 29, fascicule 2, 1955. pp. 165-166

    Psychological features and hygiene habits in supportive periodontal therapy results

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    The goal of this study was to verify the hypothesis that psychological features are related to periodontal status and to inquire into the possible pathway through which it occurs. Twenty-six patients in good systemic health and only suffering from gingivitis were recruited and treated with an 18-month follow-up. Clinical recordings, including full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), were assessed at baseline and at three-monthly periods to the end of the follow-up period. Details on oral health, attitudes and oral hygiene habits were stated. Psychological profiling was stated. Unfavorable FMPS statistical outcome was found in correlation to anxiety (A) and depression (D). Using the oral hygiene self-reported test, we observed a favorable FMPS statistical significant outcome in relation to the number of daily brushings (DB), use of toothpaste (UT), awareness of role of dental plaque (ADP) and professional dental care (PDC) and need of dental examination (NDE). Moreover, we had a favorable FMBS outcome in relation to DB and ADP. Combining psychological and hygiene tests a favorable FMPS outcome was maintained in relation to UT, ADP, PDC and NDE. Favorable FMBS was maintained in relation to DB and ADP. The study supports the hypothesis that A and D can play an unfavorable role on the periodontal status. Most probably, but not exclusively, psychological features can influence hygienic behavior through discontinuity and irregularity. ISSN: 0303-6979 (Print) - 1600-051X (Electronic) Abstract N 197, Ref no: EUABS06559

    Inhibition by anti-HLA class I mAb of IL-2 and IL-2 receptor synthesis in lymphocytes stimulated with PHA-P.

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    Inhibition by anti-HLA Class I monoclonal antibody (mAb) Q6/64 of phytohemagglutinin (PHA)-P-induced peripheral blood mononuclear cell (PMBC) proliferation is associated with a reduction of Tac expression and interleukin 2 (IL-2) secretion. To analyze the mechanism(s) underlying the latter phenomena, the Tac gene and IL-2 gene transcription was analyzed by a nuclear transcription assay. No synthesis of Tac and IL-2 mRNA was detected in PBMC stimulated with PHA-P in the presence of mAb Q6/64. In conjunction with our recently published data, these results indicate that the blocking by anti-HLA Class I mAb of PHA-P-induced PBMC proliferation reflects an inhibitory effect within the signal transduction pathway leading to transcriptional activation of IL-2 and IL-2 receptor genes

    CD40 and B chronic lymphocytic leukemia cell response to fludarabine: the influence of NF-kappaB/Rel transcription factors on chemotherapy-induced apoptosis.

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    The levels of tumour necrosis factor receptor (TNF-R) superfamily members can be altered in lymphoid leukemias, indicating a possible role of such molecules in the biology of these neoplasias. In B chronic lymphocytic leukemia cells, the CD40/CD40L system has been shown to be effective in inhibiting the apoptotic response to fludarabine. The modulation of apoptosis relied on the CD40-induced activity of NF-kappaB/Rel transcription factors. The anti-apoptotic effect of CD40 was abolished using a phosphorothioate kappaB decoy oligodeoxynucleotide. These findings illustrate an example of the biological activity of TNF-R-like molecules in leukemias. They also show the influence of NF-kappaB/Rel activity on leukemic cell response to apoptogenic agen
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