36 research outputs found
Self-assembly of vesicle nanoarrays on Si: a potential new route to high-density functional protein arrays
No full textThe authors show that 100 nm unilamellar thiol-tagged vesicles bind discretely and specifically to Au nanodots formed on a Si surface. An array of such dots, consisting of 20 nm Au–Si three-dimensional islands, is formed by self-assembly on terraces of small-angle-miscut Si111 after Au deposition. Consequently, both the formation of the nanopattern and the subsequent attachment of the vesicles are self-organized and occur without the need for any “top-down” lithographic processes. This approach has the potential to provide the basis of a low-cost,
high-density nanoarray for use in proteomics and drug discovery
Current Reform Movements in the Field of Early Childhood Education in the U. S. A. : Issues in Teacher Professionalization
No full text
Protein chip and production method thereof (US 2009/0181862)
No full textA protein chip including at least a substrate having a plurality of steps which are regularly arranged on one surface thereof; a plurality of metallic microstructures arranged in the steps; and a lipid vesicle in which an outer surface thereof is modified by a functional group and a protein is present in a lipid bilayer thereof. The metallic microstructures and the lipid vesicle are bound via the functional group to provide the protein on the substrate
Conductive polymer combined silk fiber bundle for bioelectrical signal recording.
No full textElectrode materials for recording biomedical signals, such as electrocardiography (ECG), electroencephalography (EEG) and evoked potentials data, are expected to be soft, hydrophilic and electroconductive to minimize the stress imposed on living tissue, especially during long-term monitoring. We have developed and characterized string-shaped electrodes made from conductive polymer with silk fiber bundles (thread), which offer a new biocompatible stress free interface with living tissue in both wet and dry conditions.An electroconductive polyelectrolyte, poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT-PSS) was electrochemically combined with silk thread made from natural Bombyx mori. The polymer composite 280 µm thread exhibited a conductivity of 0.00117 S/cm (which corresponds to a DC resistance of 2.62 Mohm/cm). The addition of glycerol to the PEDOT-PSS silk thread improved the conductivity to 0.102 S/cm (20.6 kohm/cm). The wettability of PEDOT-PSS was controlled with glycerol, which improved its durability in water and washing cycles. The glycerol treated PEDOT-PSS silk thread showed a tensile strength of 1000 cN in both wet and dry states. Without using any electrolytes, pastes or solutions, the thread directly collects electrical signals from living tissue and transmits them through metal cables. ECG, EEG, and sensory evoked potential (SEP) signals were recorded from experimental animals by using this thread placed on the skin. PEDOT-PSS silk glycerol composite thread offers a new class of biocompatible electrodes in the field of biomedical and health promotion that does not induce stress in the subjects
Axial/equatorial Populations In α-hetero-substituted Cyclohexanone Oximes And O-methyl Oximes
No full textAxial equatorial populations were determined for (E)-2-X-cyclohexanone oximes and O-methyl oxime ethers in chloroform by the Eliel method [X = F, Cl, Br, OCH3, N(CH3)2, SCH3]. A novel approach is presented, which uses 1H NMR data from the protons bonded to C-6. The conformational proportions were also obtained from the C-4 chemical shifts, the Z-isomer spectral parameters being taken as reference for calculation. For both series, all substituents adopt preferentially the axial conformation (86-96%), but the O-methyl oxime ethers present an enhanced axial population compared with the corresponding oximes, owing to the accepted occurrence of a πC=NOH//σ*CX stabilizing interaction. Copyright © 2000 John Wiley & Sons, Ltd.388627638Allinger, N.L., Allinger, J., Freiberg, L.A., Czaja, R.F., Lebel, N.A., (1960) J. Am. Chem. Soc., 82, p. 5876Eliel, E.L., Allinger, N.L., Angyal, S.J., Morrison, C.A., (1965) Conformational Analysis, pp. 112-115. , Interscience: New YorkBasso, E.A., Kaiser, C., Rittner, R., Lambert, J.B., (1993) J. Org. Chem., 58, p. 7865Saitô, H., Teresawa, I., Ohno, M., Nukada, K., (1969) J. Am. Chem. Soc., 91, p. 6696Denmark, S.E., Dappen, M.S., (1984) J. Org. Chem., 49, p. 798Denmark, S.E., Dappen, M.S., Sear, N.L., Jakobs, R.T., (1990) J. Am. Chem. Soc., 112, p. 3466Olivato, P.R., Ribeiro, D.S., Rittner, R., Hase, Y., Del Pra, A., Bombieri, G., (1995) Spectrochim. Acta, Part A, 51, p. 1479Eliel, E.L., (1959) Chem. Ind. (London), p. 568Durand, R., Geneste, P., Moreau, C., Pavia, A.A., (1974) Org. Magn. Reson., 6, p. 73Fraser, R.R., Capoor, R., Bovenkamp, J.W., La Croix, B.V., Pagoto, J., (1984) Can. J. Chem., 61, p. 2616Dal Colle, M., Distefano, G., Modelli, A., Jones, D., Guerra, M., Olivato, P.R., Ribeiro, D.S., (1998) J. Phys. Chem. A, 102, p. 8037Fraser, R.R., Dhawan, K.L., Taymaz, K., (1978) Org. Magn. Reson., 11, p. 269Eliel, E.L., Wilen, S.H., Mander, L.N., (1994) Stereochemistry of Organic Compounds, p. 698. , Wiley: New YorkEliel, E.L., Wilen, S.H., Mander, L.N., (1994) Stereochemistry of Organic Compounds, pp. 692-694. , Wiley: New YorkRiddell, F.G., (1974) Internal Rotation in Molecules, p. 24. , Orville-Thomas WJ (ed). Wiley: New YorkBasso, E.A., Kaiser, C., Rittner, R., Lambert, J.B., (1994) Magn. Reson. Chem., 32, p. 205Geneste, P., Durand, R., Kamenka, J.-M., Beierbeck, H., Martino, R., Saunders, J.K., (1978) Can. J. Chem., 56, p. 1940Rouillard, M., Girault, Y., Decouzon, M., Azzaro, M., (1983) Org. Magn. Reson., 21, p. 357Hoogesteger, F.J., Grove, D.M., Jenneskers, L.W., De Bruin, T.J.M., Jansen, B.A.J., (1996) J. Chem. Soc., Perkin Trans., 2, p. 2327Kalinowski, H.-O., Berger, S., Braun, S., (1988) Carbon-13 NMR Spectroscopy, pp. 109-110. , Wiley: New YorkThorpe, J.W., Warkentin, J., (1973) Can. J. Chem. Soc., 51, p. 927Allinger, N.L., Allinger, J., (1958) J. Am. Chem. Soc., 80, pp. 5476-5480Scholz, D., (1983) Synthesis, p. 944Ohno, M., Naruse, N., Torimitsu, S., Okamoto, M., (1966) Bull. Chem. Soc. Jpn., 39, p. 1119Allinger, J., Allinger, N.L., (1958) Tetrahedron, 2, p. 64Newman, M.S., Farbman, M.D., Hipsher, H., (1955) Org. Synth., Coll. Vol., 3, p. 188Bousquet, E.W., (1943) Org. Syntl., Coll. Vol., 2, p. 313Wrobel, J., Nelson, V., Surniejski, J., Kovacic, P., (1979) J. Org. Chem., 44, p. 2345Ohno, M., Torimitsu, S., Naruse, N., Okamoto, M., Sakai, I., (1966) Bull. Chem. Soc. Jpn., 39, p. 1129Hudlicky, M., Hokr, J., (1949) Collect. Czech. Chem. Commun., 14, p. 561Chow, Y.L., Colón, C.J., (1968) J. Org. Chem., 33, pp. 2598-2601Ziegenbein, W., Schäffler, A., Kaufhold, R., (1955) Chem. Ber., 88, p. 190
Selective Chemisorption of End-Functionalized Conjugated Polymer on Macro- and Nanoscale Surfaces
No full textLinear and conjugated poly(p-phenylene ethynylene)s (PPEs) with three different types of functionalized
end groups (thiolacetate, isocyanide, and carboxylic acid groups) were synthesized, and their selective
chemisorption behavior on various substrate surfaces were investigated using UV/vis transmission
absorption spectroscopy. The UV/vis spectra of the PPEs were clearly dependent on the chemical affinity
between the PPE end group and the solid surfaces. Furthermore, regarding the chemisorption of thiolacetate
modified polymer on a nanoscopic gold particle surface, we visualized novel polymer−colloid nanoarchitectures such as a barbell-type nanohybrid and interconnected polymer nanowire structures that are
successively linked through gold nanoparticles
Vapor-liquid-solid growth of vertically aligned InP nanowires by metalorganic vapor phase epitaxy
No full textIn this study, a detailed investigation of the growth of vertically oriented and surface mounted InP nanowires has been carried out. They were grown by metal organic vapor phase epitaxy on semi-insulating B-oriented InP wafers using An nanoparticle-assisted vapor-liquid-solid growth technique. The proper conditions for the stable nanowire growth were obtained by systematic variation of the pre-growth annealing and the growth temperatures and were found to be 540 and 440 degreesC, respectively. The variation in the length of the nanowires was also studied as a function of time. Transmission electron diffraction studies carried out on the single nanowires revealed the growth direction with the presence of rotational twin structures, the axis of rotation being the growth direction. Analysis of the high-resolution transmission electron microscopic images shows that the orientation and kinks on the nanowires were controlled by the distribution of these twin structures. (C) 2004 Elsevier B.V. All rights reserved
