1,720,968 research outputs found

    L'anziano fragile : perché vaccinare contro lo Pneumococco?

    No full text
    Streptococcus Pneumoniae is the main etiological agent of pneumonia and causes various other pathologies, e.g. meningitis and otitis, following to the uncontrolled replication in the human organism. The problem of treating the infection is tied to aspects that involve, on the one side the micro organism, that often develops resistance to the antibiotic, and on the other the stricken subjects that, often elderly or with pre-existing pathological conditions, don't succeed in fighting the infection with their own immune system. With the purpose to obviate to these problems and contemporarily checking the sanitary expense, a preventive practice from the long history but from the alternate fortunes, the pneumococcal vaccination, has spread more and more and recommended. In our article we would like to describe the motivations that induce us to hold the pneumococcal vaccination a usefull resource in the current socioeconomic picture for the western physician. © Pio Albergo Trivulzio

    The role of mucosal immunity: An update

    No full text
    There is considerable evidence that the mucosa associated lymphoid tissues (MALT) of the body play an active part in triggering off and conducting the immune system's response to both viral and bacterial pathogens. Effectors are capable of intercepting the micro-organisms and rendering them harmless before they penetrate through the mucous membranes, or of expelling and inactivating them after they have penetrated. The system is consequently useful both in the prevention of infection and in the humoral or cellulo-mediated immune response. These operations, whose principal protagonists are Immunoglobulins A and dendritic cells, are made possible by the high degree of functional interconnection which binds the effectors of the system and the anatomical structures located in the mucosae. The data provided in literature consequently infer that appropriate stimulation of mucosal immunity, which takes into account the new acquisitions in the field of immunology, can enable oral vaccination to overcome the obstacles encountered up till now in terms of insufficient protection against diseases. Copyright © by BIOLIFE

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Get PDF
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

    Get PDF
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Get PDF
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
    corecore