1,087 research outputs found
Are You Being Rejected or Excluded? Insights from Neuroimaging Studies Using Different Rejection Paradigms
No full textRejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim of the current review was to determine key brain regions involved in social rejection by selectively reviewing neuroimaging studies that employed one of three paradigms of social rejection, namely social exclusion during a ball-tossing game, evaluating feedback about preference from peers and viewing scenes depicting rejection during social interaction. A cross the different paradigms of social rejection, there was concordance in regions for experiencing rejection, namely dorsal anterior cingulate cortex (ACC), subgenual ACC and ventral ACC. Functional dissociation between the regions for experiencing rejection and those for emotion regulation, namely medial prefrontal cortex, ventrolateral prefrontal cortex (VLPFC) and ventral striatum, was evident in the positive association between social distress and regions for experiencing rejection and the inverse association between social distress and the emotion regulation regions. The paradigms of social exclusion and scenes depicting rejection in social interaction were more adept at evoking rejection-specific neural responses. These responses were varyingly influenced by the amount of social distress during the task, social support received, self-esteem and social competence. Presenting rejection cues as scenes of people in social interaction showed high rejection sensitive or schizotypal individuals to under-activate the dorsal ACC and VLPFC, suggesting that such individuals who perceive rejection cues in others down-regulate their response to the perceived rejection by distancing themselves from the scene
N-15 MR Hyperpolarization via the Reaction of Parahydrogen with 15N-Propargylcholine
No full text15N-Propargylcholine has been synthesized and hydrogenated with para-H2. Through the application of a field cycling procedure, parahydrogen spin order is transferred to the 15N resonance. Among the different isomers formed upon hydrogenation of 15N-propargylcholine, only the nontransposed derivative contributes to the observed N-15 enhanced emission signal. The parahydrogen-induced polarization factor is about 3000. The precise identification of the isomer responsible for the observed 15N enhancement has been attained through a retro-INEPT (15N–1H) experiment. T1 of the hyperpolarized 15N resonance has been estimated to be ca. 150 s, i.e., similar to that reported for the parent propargylcholine (144 s). Experimental results are accompanied by theoretical calculations that stress the role of scalar coupling constants (JHN and JHH) and of the field dependence in the formation of the observed 15N polarized signal. Insights into the good cellular uptake of the compound have been gained
Data for The colloidal nature of complex fluids enhances bacterial motility
No full textThe archived data are the post-processed final data corresponding to figures in the manuscript as well as codes used for generating key plots.IPRIME at University at Minnesota. US National Science Foundation CBET-1702352 and 2028652Kamdar, Shashank; Shin, Seunghwan; Leishangthem, Premkumar; Francis, Lorraine F; Xu, XinLiang; Cheng, Xiang. (2022). Data for The colloidal nature of complex fluids enhances bacterial motility. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/nfr5-te36
CVD of Ru, Pt and Pt-based alloy thin films using ethanol as mild reducing agent
No full text3 Premkumar, P. Antony Prakash, N. S. Gaillard, F. Bahlawane, N.Noble metal thin films (Pt and Ru) were grown at 250 degrees C, using commercially available precursors, by the pulsed spray evaporation chemical vapor deposition (PSE-CVD) technique. The growth process relies on the thermally activated reaction of ethanol with the metal acetylacetonate precursors. The synthesized polycrystalline films are pure metal phase and crystallize in hexagonal (Ru) and cubic (Pt) structures. The formation of an interfacial suicide phase was noticed in the case of the Pt growth on silicon substrates. The films are smooth, continuous and show a steady growth without any noticeable incubation time. The single-step growth of Pt-based alloys, Pt-Co and Pt-Cu, with controlled composition was performed by simply adjusting the composition of the liquid feedstock. (C) 2010 Elsevier B.V. All rights reserved
Clinical application of palatal lift appliance in velopharyngeal incompetence
No full textThe presence of nasal air leak in cleft palate patients with velopharyngeal incompetence leads to characteristic nasal snort. The efficacy of the palatal lift appliance in patients with adequate velopharyngeal tissue with incompetence was tested. Speech quality improved after the wearing of palatal lift appliance. Palatal lift appliances are simple and efficient in reducing the nasal air leak. Ongoing speech therapy is necessary and advised for patients receiving palatal lift
Supplemental Material - Perceptions and Expectations Regarding the Step 1 Score Change Among Surgical and Non-Surgical Program Directors: A Systematic Review and Meta-Analysis
No full textSupplemental Material for Perceptions and Expectations Regarding the Step 1 Score Change Among Surgical and Non-Surgical Program Directors: A Systematic Review and Meta-Analysis by Nitin Srinivasan, BA, Jamil S. Samaan, MD, Agnes Premkumar, MD, Nithya D. Rajeev, BS, Yee Hui Yeo, MD, MSc, and Kamran Samakar, MD, MA in The American Surgeon™.</p
Intensification and performance assessment of the formic acid production process through a dividing wall reactive distillation column with vapor recompression
No full textDistillation operation in the production of formic acid (FA) involves a large amount of investment and has high-energy requirements. Thus, process intensification is crucial in minimizing the energy consumption and investment. Dividing wall column (DWC) is one such way of achieving it. Aim of this study is to design a dividing wall reactive distillation column (DWRDC) with vapor recompression in the production of FA instead of normal reactive distillation â distillation sequence and investigate the performance in terms of energy, cost, and carbon emission. A patented FA production process is chosen as a base case. The intensification of the base case FA production process is then carried out through the application of (i) DWRDC, (ii) vapor recompression in a distillation column, and (iii) vapor recompression in DWRDC. The performance of the new intensified processes is subsequently investigated for multiple performance indexes. It is observed that an impressive saving of 18.33% in utility cost, 8.4% in total annual cost (TAC), 2.55% in cost of manufacturing (COM), and 17.68% in carbon emission can be secured with the proposed new intensification as compared to its conventional counterpart for a payback period of 4 years
Audio-recodings of criticism, praise, and neutral comments
No full text<p>An auditory instrument of 100 criticisms, 100 praises, and 100 neutral comments was developed following the conventions for expressed emotion (EE)-criticism and EE-positive comments (Leff & Vaughn, 1985) and following the themes contained in the criticism and praise from an earlier study (Premkumar, et al., 2013). In addition to criticism and praise, neutral comments were designed as a general non-emotional control, and related to topics such as the weather, historical facts, and scientific facts. For example, ‘Today’s weather forecast suggests outbreaks of rain across the north, gradually easing with places becoming dry with sunny spells.’ The number of words per comment ranged from 18 to 20. A male actor and a female actor recorded the comments on a digital voice recorder. The male (AD) and female actors (PP) had a similar age and a similar length of experience in conducting psychological research. When the comments were delivered, the actors were trained to vary the prosodic variables (tone and pitch) to emphasise affective differences between the three types of comments. This was achieved by practising the tone of the voice for each comment type prior to recording. One actor (PP) was trained to rate EE using the CFI, and assessed the consistency of affect between the actors. The actors re-recorded the comments to address any differences in affective expression. </p>
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