1,721,128 research outputs found
Transversal mandibular deficiency and Osteogenetic distraction
No full textThe Authors describe the orthodontic use of a fixed mandibular distraction screw and its advantages, which are clearly evident when looked at in the light of the final results. The proposed appliance makes it possible to achieve stable expansion, and is comfortable and safe for patients; the use of laser soldering also makes it biocompatible
Conformational analysis of 9-deoxydaunorubicin in solution : The application of a quantitative transient 1H nuclear Overhauser effect
No full textThe preferred conformation of 9-deoxy-N-trifluoroacetyldaunorubicin has been determined by 1H and 13C n.m.r. in CDCl3 solution. The conformation of ring A was easily defined as a pure half-chair 9H8, from the values of proton coupling constants, and on the basis of a preceding study of daunomycin derivatives. The orientation of the sugar with respect to the aglycone moiety has been obtained by quantitative transient nuclear Overhauser experiments (n.O.e.). The interproton distances have been deduced from the cross-relaxation rates determined by measuring the time development of n.O.e.s, after selective inversion of single resonances. The experimental points were fitted to the theoretical curves through a non-linear least-squares procedure. The overall isotropic motion was proved by 13C T1 measurements of all protonated carbons; the interproton reference distance r4′–5′, deduced from the correlation time value, is in satisfactory agreement with those measured by X-ray analyses of daunomycin and carminomycin. The glycoside linkage geometry has also been expressed in terms of the rotational angles φ= H(1′)–C(1′)–O(7)–C(7) and ψ= C(1′)–O(7)–C(7)–H(7). The results have been compared with those obtained through molecular mechanics calculations, performed with the Allinger MMP2 program
Resistance to corrosion in brazed and laser welded orthodontic: an in vitro study
No full textThe aim of this study was to compare the corrosion resistance of the stainless steel when traditionally soldered and when laser welded. This research represent a part of a large study
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926
No full textST1926 is a novel related adamantyl retinoid endowed with potent antiproliferative and apoptogenic activity. The drug induced an early G1/S cell cycle arrest which was assocd. with a typical DNA damage response including modulation of genes involved in cell cycle regulation and DNA repair. The evidence of the drug ability to induce a significant extent of DNA strand breaks after short-term exposure is consistent with the cellular response. ST1926 is active by oral administration both on hematol. and on solid tumors. The more marked antitumor effect showed by ST1926 in immuno-competent mice rather than in tumor xenografts suggests a contribution of indirect host-mediated antitumor effects in addn. to a direct antiproliferative activity against tumor cells
A nuclear factor that Down-Modulates the Granulocyte-Macrophage Colony-Stimulating Factor Expression.
No full text- …
