1,280 research outputs found
Musto, C W, 406149
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/407075Surname: MUSTO. Given Name(s) or Initials: C W. Military Service Number or Last Known Location: 406149. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 41200.243141
Item: [2016.0049.39350] "Musto, C W, 406149
La perífrasis de infinitivo con el verbo ir en castellano comparada con otras variedades (ibero)romances: un estudio diacrónico.
No full textEl desarrollo del latín hacia las lenguas románicas siempre se ha percibido como un movimiento que de un proceso de síntesis lleva a un proceso de análisis, pero avanza con siempre mayor fuerza la hipótesis de que “la organización analítica de la expresión es una característica tipológica fundamental del latín vulgar” (García Hernández, 309) y no solo de las lenguas que de ella descienden, puesto que muchas de las formas analíticas presentes en las lenguas romances ya existían como formas perifrásticas en latín. A eso cabe añadir que el proceso no fue unidireccional, sino cíclico, es decir, que a una forma sintética procedente de la aglutinación de una forma analítica, casi siempre se acompañaba la gramaticalización de una forma analítica menos opaca que la forma sintética anterior. Ese es el caso del futuro sintético del latín clásico cantabo procedente de la aglutinación de unidades léxicas distintas: la forma resulta de la agregación de un parte radical canta-, que funciona como sustantivo verbal, más el sufijo -b-, procedente del imperfecto de indicativo y que funciona como presente temático, más el sufijo desinencial de primera persona singular -o (Cupaiuolo, 218-219). Luego fue sustituido por la perífrasis cantāre habĕo, que tras su fusión dará el futuro sintético castellano ‘cantaré’ al que finalmente se acompaña la perífrasis ‘voy a cantar'
Marcello Musto, 2018, Another Marx: Early Manuscripts to the International.
No full textPaula Rauhala arvioi Marcello Muston teoksen: Marcello Musto: Another Marx: Early Manuscripts to the International. Kääntänyt Patrick Camiller. Bloomsbury Academic 2018. 288 s
Introducción
No full textSi tratta dell'introduzione al volume curato; è scritta in spagnolo, mentre il volume è plurilingue, con la maggior parte dei testi in spagnolo e alcuni in francese e in inglese
El papel del enunciador en la determinación del valor sistémico del condicional en español y en italiano
No full textEl objetivo del presente trabajo es tratar de entender cuáles han sido las elecciones previas que han efectuado los enunciadores de las dos lenguas, español e italiano, y que han llevado al nacimiento de los dos condicionales aparentemente semejantes: el condicional del español (compartido por la mayoría de las lenguas romances), que se sirve de la terminación del imperfecto, y el del italiano, para el que en cambio se ha usado la terminación del pasado simple.
The aim of the present work is to understand how the previous choices made by the enunciators of the two languages, Spanish
and Italian, had influenced the birth of the two apparently similar verbal forms: the Spanish conditional (shared by most of the romance languages), which uses the ending of the imperfect tense, and the Italian which, instead, uses the simple past tense
Microvesicles: neuroglial unconventional signaling to cortical brain cells
No full textExtracellular vesicles (EVs) represent an alternative and recently discovered way by which diverse cell phenotype can deliver complex messages through released vesicles and their cargoes to neighbor or distant targets. EVs mediate fundamental physiological and pathological processes in biological systems.
In particular, we focused on neuron-glia communication mediated by microvesicles (MVs), a subpopulation of EVs that directly originate by outward budding of cellular plasma membrane, which are mostly released under specific stimuli. Given the nanosized dimension and origin of MVs, we tested the ability of carbon-based nanomaterial (small graphene oxide nanoflakes, s-GO), which are demonstrated to interface cells and interact with their physiology at the level of their plasma membrane, to affect the mechanisms governing vesicles release. We first investigated whether s-GO affected the ability of astrocytes to release synaptic-like MVs in pure glial cultures. Our results describe the potential of GO nanosheets to alter different modes of interneuronal communication systems in the central nervous system (CNS). We further tested the reactivity of microglia, a sub-population of neuroglia that acts as the first active immune response, when challenged by chronic s-GO delivery at high doses. We investigated the tissue reactivity in 3D tissue models by using organotypic spinal cord cultures, ideally suited for studying long-term interference with cues delivered at controlled times and concentrations and in isolated neuroglia cultures. In the latter condition, we further tested the role of microglial micro-vesicle release in mediating cell responses to s-GO. Finally, starting from the observation that small graphene oxide flakes (s-GO) are able to boost MVs basal release in cortical glial cells of rodents after a sub-chronic treatment of 6-8 days, we compared through the use of highly sensitive and resolutive nanotechnological tools, MVs obtained under s-GO exposure with MVs obtained by stimulation with the purinergic agonist bzATP, known to induce such release in glial cells. The structural and macromolecular similarities found, suggested a comparable nature of s-GO-derived MVs with the bzATP-derived ones, despite the unusual induction of release. We finally investigated the acute effects of those populations of vesicles exerted on single cortical neurons by focusing on their synaptic activity. We found that both the MVs types
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induced an increase in spontaneous post synaptic currents (PSCs) on neurons, after 15 minutes from MVs administration
Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events
No full textLin28 RNA-binding proteins play important roles in pluripotent stem cells, but the regulation of their expression and the mechanisms underlying their functions are still not definitively understood. Here we address the above-mentioned issues in the first steps of mouse embryonic stem cell (ESC) differentiation. We observed that the expression of Lin28 genes is transiently induced soon after the exit of ESCs from the naive ground state and that this induction is due to the Hmga2-dependent engagement of Otx2 with enhancers present at both Lin28 gene loci. These mechanisms are crucial for Lin28 regulation, as demonstrated by the abolishment of the Lin28 accumulation in Otx2- or Hmga2-knockout cells compared to the control cells. We have also found that Lin28 controls Hmga2 expression levels during ESC differentiation through a let-7-independent mechanism. Indeed, we found that Lin28 proteins bind a highly conserved element in the 3' UTR of Hmga2 mRNA, and this provokes a down-regulation of its translation. This mechanism prevents the inappropriate accumulation of Hmga2 that would modify the proliferation and physiological apoptosis of differentiating ESCs. In summary, we demonstrated that during ESC differentiation, Lin28 transient induction is dependent on Otx2 and Hmga2 and prevents an inappropriate excessive rise of Hmga2 levels.-Parisi, S., Passaro, F., Russo, L., Musto, A., Navarra, A., Romano, S., Petrosino, G., Russo, T. Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events
How to contrast and maintain information in Spanish and Italian, as L1s and L2s
No full textThe purpose of the paper is to analyse the way informants change or contrast information in the Topic Entity and Topic Time domains (Klein 2008) in Italian and Spanish, as L1s and L2s. In the narrative task proposed, informants also have to maintain predicative information, since a process claimed to hold for some Topic Entities and Topic Times is actually ma
intained from previous discourse.
The data have been elicited using the video clip The Finite Story (Dimroth 2006) and are divided in four groups: Spanish L1, Italian L1, Spanish L2 of Italian learners, Italian L2 of Spanish learners.
Dimroth et al. (2010) have analysed Finite Story narrations of German, Dutch, French and Italian adult native speakers, identifying the type of items signalling which parts of the information are maintained and which parts have been changed or contrasted. The anaphoric linking devices range from additive particles to polarity or temporal contrasting markings and to prosodic devices. The same authors suggest that: when a polarity contrast is present, Dutch and German mark this polarity contrast much more frequently than Romance languages, which prefer to mark the contrast on the topic component (entity or time).
Benazzo & Andorno (2010) extended the debate to Italian and French as L2s. Giuliano (2012) tested Dimroth et al.’s hypothesis on English, both as L1 and L2 (all the author used The Finite Story task), suggesting that English native speakers select cohesive means much closer to those preferred by Romance than Germanic speakers. All the authors explored crosslinguistic interferences.
Now, our purpose in the present paper is to furtherly extend the debate to Spanish, as L1 and L2, and to Spanish of Italian learners. We shall demonstrate that Spanish is in many ways closer to Germanic than to Romance languages since its native speakers tend to often highlight the polarity contrast, despite the absence in their L1 of specifically grammaticised means for this purpose; they also tend to transfer this type of contrast in Italian L2, whereas the polarity contrast is absent in the Spanish L2 of Italian speakers.
Bibliography
Benazzo, S. & Andorno, C. 2010. Discourse cohesion and topic discontinuity in native and learner production: changing topic entities on maintained predicates. In L. Roberts, M. Howard, M. O'Laoire & D. Singleton (éds.) Eurosla Yearbook 10 (92-118). Amsterdam: John Benjamins.
Dimroth, Christine, 2006. The Finite Story. Max-Planck-Institute for Psycholinguistics, http://corpus1.mpi.nl/ds/imdi_browser?openpath=MPI560350%23
Dimroth, Christine / Andorno, Cecilia / Benazzo, Sandra / Verhagen, Josie (2010), “Given claims about new topics. The distribution of contrastive and maintained information in Romance and Germanic Languages”, Journal of Pragmatics 42: 3328-3344.
Giuliano, P. (2012), “Contrasted and maintained information in a narrative task: analysis of texts in English and Italian as L1s and L2s”, EUROSLA Yearbook 2012, Amsterdam, John Benjamins, vol. 12: 30-62.
Klein, Wolfgang, 2008, “The topic situation”. In: Ahrenholz, B. et al. (Eds.), Empirische Forschung
und Theoriebildung. Festschrift für Norbert Dittmar zum 65. Geburtstag. Frankfurt a.M., Peter Lang, pp. 287-306
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