142 research outputs found
Urgent and elective proctologic/anorectal interventions in the covid-19 pandemic: A practical guideline for treatment safety
No full textBACKGROUND: This article aims to give practical information and concrete suggestions on what should be considered in emergen-cy, semi-urgent and elective settings for common anorectal diseases in the hectic period of the COVID-19 pandemic, based on early results of a series of anorectal interventions. METHODS: Referring to other related guidelines, general considerations specific to the diagnosis and treatment of highly prevalent anorectal diseases were developed to target the correct patients, evaluate and orientate by telemedicine, adapt the Proctology Unit to the new pandemic, and control contamination and infection. Specific considerations for common anorectal diseases were cited, and our initial results were retrospectively documented. RESULTS: From March 1 to April 10, 2020, we contacted 240 patients with anorectal diseases in two centers. We evaluated the results retrospectively on 16–17 April. At the end of this survey, 14 patients (5.8%) were lost for further contact and follow-up. Thir-ty-one patients (12.9%) were evaluated as nondeferrable cases and invited to the Proctology Unit. Twenty-eight patients required interventions at the same session. Adhering to the principles described here, more than 90 percent of benign anorectal disorders could be treated successfully, with 2.1 percent of suspected contamination and no confirmed cases. None of the Proctology personnel or their close contacts developed COVID-19, either. CONCLUSION: By adhering to the principles outlined in this practical guide, it was possible to treat most of the benign anorectal diseases safely in the initial, hectic period of the COVID-19 pandemic
AGGRESSIVE SURGICAL MANAGEMENT OF GIANT CONDYLOMA ACUMINATUM OF BUSCHKE AND LoWENSTEIN: LONG-TERM RESULTS OF 11 CASES.
No full textA different look on the importance of lateralization and localization of figure 4 symptoms in epilepsy
No full textBackground Clinical seizure semiology provides valuable information in the evaluation of focal-onset bilateral tonic-clonic seizures. In the evaluation of these patients, long-term video-EEG monitoring (VEM) and neuroimaging studies are of great significance in determining lateralization together with clinical semiology. In this study, we examined the features of the figure 4 sign that we detected in patients with refractory epilepsy whom we followed up in the VEM unit. Methods In the study, 175 patients followed in the VEM unit were examined. Twenty-two patients for whom the figure 4 sign was detected were included in the study. Patients with the side indicated by the figure 4 sign comply with ictal EEG compatible were named as 1st group (G1), and those not were named as 2nd group (G2). Demographic characteristics, seizure type, number of seizures per month, duration of epilepsy, number of seizures during VEM, duration of figure 4 sign, medical history, and cranial MRI characteristics were compared between the two groups. Results When G1 and G2 were compared, it was observed that temporal lobe seizures were statistically significantly higher in G1. When the figure 4 sign durations were examined, this period was 16.3 +/- 8.2 s in frontal lobe seizures and 20.8 +/- 7.4 s in temporal lobe seizures. When the duration of the figure 4 sign was examined by gender, it was found that the duration was longer in males, which was statistically significant. Conclusion In conclusion, it is essential to evaluate ictal EEG findings together with brain imaging while performing semiological localization and lateralization in epileptic patients
European Society of Coloproctology: Guidelines for diagnosis and treatment of cryptoglandular anal fistula
No full textAim: The primary aim of the European Society of Coloproctology (ESCP) Guideline Development Group (GDG) was to produce high-quality, evidence-based guidelines for the management of cryptoglandular anal fistula with input from a multidisciplinary group and using transparent, reproducible methodology. Methods: Previously published methodology in guideline development by the ESCP has been replicated in this project. The guideline development process followed the requirements of the AGREE-S tool kit. Six phases can be identified in the methodology. Phase one sets the scope of the guideline, which addresses the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula in adult patients presenting to secondary care. The target population for this guideline are healthcare practitioners in secondary care and patients interested in understanding the clinical evidence available for various surgical interventions for anal fistula. Phase two involved formulation of the GDG. The GDG consisted of 21 coloproctologists, three research fellows, a radiologist and a methodologist. Stakeholders were chosen for their clinical and academic involvement in the management of anal fistula as well as being representative of the geographical variation among the ESCP membership. Five patients were recruited from patient groups to review the draft guideline. These patients attended two virtual meetings to discuss the evidence and suggest amendments. In phase three, patient/population, intervention, comparison and outcomes questions were formulated by the GDG. The GDG ratified 250 questions and chose 45 for inclusion in the guideline. In phase four, critical and important outcomes were confirmed for inclusion. Important outcomes were pain and wound healing. Critical outcomes were fistula healing, fistula recurrence and incontinence. These outcomes formed part of the inclusion criteria for the literature search. In phase five, a literature search was performed of MEDLINE (Ovid), PubMed, Embase (Ovid) and the Cochrane Database of Systematic Reviews by eight teams of the GDG. Data were extracted and submitted for review by the GDG in a draft guideline. The most recent systematic reviews were prioritized for inclusion. Studies published since the most recent systematic review were included in our analysis by conducting a new meta-analysis using Review manager. In phase six, recommendations were formulated, using grading of recommendations, assessment, development, and evaluations, in three virtual meetings of the GDG. Results: In seven sections covering the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula, there are 42 recommendations. Conclusion: This is an up-to-date international guideline on the management of cryptoglandular anal fistula using methodology prescribed by the AGREE enterprise
Correction to:Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY) (International Journal of Colorectal Disease, (2025), 40, 1, (194), 10.1007/s00384-025-04921-x)
No full textThe collaborative Author names are missing in the published proof. The Supplementary material is updated with 2 additional names in the collaborative Author’s list. Ali Yalcinkaya, Ahmet Yalcinkaya, Sezai Leventoglu, Bengi Balci, Alp Ozgun Borcek, Elif Ozeller, Ece Ozturk, Gulsum Sueda Kayacan, Berkay Enes Karaca, Ahmet Faruk Oyanik, Omer Faruk Gul, Basak Bolukbasi, Huseyin Gobut, Cagri Buyukkasap, Aydin Yavuz, Dara Aydin, Zeynep Akdagcik, Alina Pataeva, Douigou Hasan, Omar Hussein, Arda Ozgur Ozturk, Cem Arda Elumar, Ali Derman Dere, Asra Zeynep Balci, Rasim Ozturk, Yasar Copelci, Murat Kartal, Serkan Tayar, Mustafa Yeni, Tolga Kalayci, Ramazan Yavuz, Bulent Calik, Semra Demirli Atici, Selen Ozturk, Gizem Kilinc, Korhan Tuncer, Cengiz Aydin, Mustafa Yener Uzunoglu, Alp Yildiz, Aybala Yildiz, Can Sahin, Mehmet Caglikulekci, Elbrus Zarbaliyev, Murat Sevmis, Baris Sevinc, Nurullah Damburaci, Omer Karahan, Ozgen Isik, Said Kural, Xhenet Hysejni, Ahmet Aktas, Baris Yildiz, Gultekin Ozan Kucuk, Ahmet Can Sari, Mert Candan, Mehmet Mahir Ozmen, Cem Emir Guldogan, Emre Gundogdu, Munevver Moran, Mevlut Recep Pekcici, Saygin Altiner, Enes Cebeci, Tugba Yigit, Bedri Burak Sucu, Mert Col, Omer Faruk, Ozkan Hanife, Seyda Ulgur, Murat Kalin, Emre Furkan Kirkan, Abdullah Yildiz, Sema Yukseksag, Cagri Buyukkasap, Erdinc Kamer, Mesut Ozogul, Nihan Acar, Melek Gokova Bekler, Arif Atay, Halis Bag, Server Sezgin Uludag, Ahmet Necati Sanli, Sefa Ergun, Ergin Erginoz, Veysi Basbayandur, Mehmet Faik Ozcelik, Ahmet Askar, Yuksel Altinel, Adnan Hacim, Serhat Meric, Merve Tokocin, Talar Aktokmakyan, Yunus Aktimur, Kamil Ozdogan, Fikret Calikoglu, Tugba Koc Calikoglu, Ahmet Barcin, Ahmed Salhat, Guray Durmaz, Volkan Ozben, Erman Aytac, Zumrud Aliyeva, Arda Ulas Mutlu, Mert Tanal, Mustafa Fevzi Celayir, Aydin Eray, Tufan Ali Yuksel, Elif Baran, Banu Yigit, Erhan Eroz, Aykhan Abbasov, Hakan Yanar, Huseyin Onur Aydin, Murathan Erkent, Tugan Tezcaner, Tevfik Avci, Murat Kus, Mehmet Abdussamet Bozkurt, Adem Ozcan, Nezihe Berrin Dodur Onalan, Serhan Yilmaz, Yasin Kara, Ali Kocatas, Fatih Yanar, Ali Fuat Kaan Gok, Irem Karatas, Berke Sengun, Ilknur Erenler Bayraktar, Onur Bayraktar, Zulal Emsal, Irem Dalkilic, Cengiz Dibekoglu, Sami Acar, Erman Ciftci, Yunus Yapalak, Cihad Tatar, Mert Mahsuni Sevinc, Ali Emre Nayci, Egemen Saygili, Yavuz Selim Komek, Bayram Kaymak, Fatih Altintoprak, Emrah Akin, Necattin Firat, Emre Gonullu, Ugur Can Dulger, Atilla Kurt, Sinan Soylu, Musa Serin, Omer Topcu, Ali Cihat Yildirim, Mehmet Fatih Ekici, Sezgin Zeren, Ismail Ahmet Bilgin, Tayfun Karahasanoglu, Ismail Hamzaoglu, Afag Aghayeva, Bilgi Baca, Inci Sahin, Osman Bozbiyik, Mustafa Ozgur Kilincarslan, Mustafa Ali Korkut, Erhan Akgun, Cemil Caliskan, Tayfun Yoldas, Timucin Erol, Hilmi Anil Dincer, Omer Cennet, Muhammed Salih Suer, Muhammet Bunyamin Dalkilic, Ibrahim Alkan, Busenur Kirimtay, Emre Balik, Emre Ozoran, Ibrahim Halil Ozata, Derya Salim Uymaz, Tutku Tufekci, Salih Nafiz Karahan, Orhan Agcaoglu, Naciye Cigdem Arslan, Mehmet Yilmaz, Orhan Ureyen, Can Murat Kale, Enver Ilhan, Eray Kara, Semra Tutcu Sahin, Onur Haspolat, Alperen Dalkiran, Ergun Yuksel, Mehmet Kocaoglu, Omer Tasan, Cevdet Tokat, Cihan Ozen, Alptug Mertcan Koc The Original article has been corrected.</p
RESULTS OF (TST (TM)) STARR FOR OBSTRUCTIVE DEFECATION DISORDERS SUCH AS RECTOCELE AND INTERNAL RECTAL PROLAPSUS.
No full textBargaining and Conflict with Incomplete Information
No full textThis paper studies bargaining and conflict under incomplete information, provides an overview and a critical account of the literature on the topic and contributes with original research. We first revise models of mechanism design and sequential bargaining that take confrontation as final. Conflict and inefficiencies are to be expected in these models whenever parties have optimistic prospects on the outcome of the all-out conflict. After examining the causes and reasons for this optimism, we move to the analysis of the recent literature that considers the existence of limited confrontations that allow bargaining to resume. In the presence of private information, these limited conflicts convey information and thus become a bargaining instrument. The paper closes with a discussion on the related empirical literature, the challenges that it faces and some potential avenues for further research.Bargaining, Conflict, Incomplete information, Power, Optimism, Hicks paradox, Uneven contenders paradox.
Cyclosporine-A induced neurotoxicity after renal transplantation
No full textCyclosporine-A is a highly potent immunosuppressive agent for solid organ transplantation, but has many side effects including nephrotoxicity, hypertension, gum hyperplasia, hepatotoxicity, and neurotoxicity. Neurotoxicity is a less known toxic effect. The pathogenesis of this effect is unclear. However, it has been postulated that hypomagnesemia, hypocholesterolemia, corticosteroids, and/or neurotoxic substances can induce this syndrome. Also, it has been suggested that the endothelial damage caused by Cyclosporine-A may contribute to neuropeptide-mediated ischemia in the brain and lead to the development of neurological symptoms. In this report, we present a case with reversible neurologic deficits whose symptoms returned to normal after the cessation of cyclosporine-A
- …
