1,720,980 research outputs found
Antiretroviral therapy during pregnancy
- Treatment with zidovudine has led to a fall in the mother-to-child HIV transmission during pregnancy and the first few weeks of neonatal life. - Ongoing trials are assessing the preventive efficacy of two-drug and three-drug antiretroviral regimens in this setting. - Pending the results of these studies, treatment with zidovudine is recommended for all HIV-infected pregnant women. - Current therapeutic strategies may lead to the prescription or continuation of multidrug antiretroviral regimens for seropositive pregnant women. - Available information on the possible adverse effects of antiretroviral drugs on the pregnant woman, fetus and child are limited. - Two reports propose similar guidelines for the management of seropositive pregnant women and their children during the first weeks of life
HIV-discordant couples start to use condom when they plan to have a child.
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The perineal flora of women according to their method of genital cleansing
Objective: The use of bidet for genital cleansing is common in our Country and we wanted to evaluate the effect of this method of ablution on the resident perineal flora. Methods: We analysed the perineal flora of 174, fertile, sexually active women who answered a questionnaire about their use of the bidet and about specific factors that could have influenced the type of microorganism residing on the external genitalia. Results: Three quarters of the women resulted to be habitual users of the bidet, while the remaining never used it. Recurrent genital inflammation was more common in women who never use the bidet, but this women had also referred in more cases than habitual users to have partners with recurrent genital infection. The predominant growth of Gram-nagative germs and the presence of Candida albicans on the external genitalia was significantly higher in women who never used the bidet. No significant differences was however observed in the prevalence of single bacterial species between the two groups of women. Conclusion: Our data suggest that the methods of genital ablution can influence the bacterial flora residing between the genito-crural folds. The use of the bidet could have a protective effect against infection of the external mucosa and may reduce the incidence of episodes of infective vulvo-vaginitis which are a common problem in sexually active women
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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