261 research outputs found
De imitatione Christi
No full textlibros quatuor, redactos in seriem dominicalem et festivalem per annum, cum locis scripturae sacrae, inde convenientibus orationibus, libello precum et indice capitum edidit Fr. Henricus Gossler. [Überlieferter Verf.: Thomas a Kempis]Enth. außerdem: De vita Christi, sanctissimi redemptoris, Jesu Nazareni, filii Dei, magni Dei et salvatoris nostri : secundum scripturas et patrum interpretationes, libri quatuor, in serie dominicali et festivali / auctore Henrico MagdeburgensiHenricus [Ordensname] s. Gossler, Friedrich Franz Theodor Heinric
Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12
No full textThe distal portion of mouse chromosome 12 is imprinted. To date, however, Gtl2 is the only imprinted gene identified on chromosome 12. Gtl2 encodes multiple alternatively spliced transcripts with no apparent open reading frame. Using conceptuses with maternal or paternal uniparental disomy for chromosome 12 (UPD12), we found that Gtl2 is expressed from the maternal allele and methylated at the 5' end of the silent paternal allele. A reciprocally imprinted gene, Delta-like (Dlk), with homology to genes involved in the Notch signalling pathway was identified 80kb upstream of Gtl2. Dlk was expressed exclusively from the paternal allele in both the embryo and placenta, but the CpG-island promoter of Dlk was completely unmethylated on both parental alleles. Rather, a paternally methylated region was identified in the last exon of the active Dlk allele. The proximity, reciprocal imprinting and methylation in this domain are reminiscent of the co-ordinately regulated Igf2-H19 imprinted domain on mouse chromosome 7. Like H19 and Igf2, Gtl2 and Dlk were found to be co-expressed in the same tissues throughout development, though not after birth. These results have implications for the regulation, function and evolution of imprinted domains
Gingin high optical power test facility
No full textCopyright © Institute of Physics and IOP Publishing Limited 2006.The Australian Consortium for Gravitational Wave Astronomy (ACIGA) in collaboration with LIGO is developing a high optical power research facility at the AIGO site, Gingin, Western Australia. Research at the facility will provide solutions to the problems that advanced gravitational wave detectors will encounter with extremely high optical power. The problems include thermal lensing and parametric instabilities. This article will present the status of the facility and the plan for the future experiments.C. Zhao, D.G. Blair, P. Barriga, J. Degallaix, J-C Dumas, Y. Fan, S. Gras, L. Ju, B. Lee, S. Schediwy, Z. Yan, D.E. McClelland, S.M. Scott, M.B. Gray, A.C. Searle, S. Gossler, B.J.J. Slagmolen, J. Dickson, K. McKenzie, C. Mow-Lowry, A. Moylan, D. Rabeling, J. Cumpston, K. Wette, J. Munch, P.J. Veitch, D. Mudge, A. Brooks, and D. Hoske
A Community Schools Approach to Accessing Services and Improving Neighborhood Outcomes in Manchester, NH
No full textThis brief uses data collected by the Manchester Health Department in 2013 and analyzed by the Carsey School of Public Policy in the Bakersville, Beech Street, and Gossler Park neighborhoods in Manchester, New Hampshire, to provide information about how barriers to various dimensions of well-being differ by place and also across race/ethnicity, foreign-born status, and age. Survey data and focus groups also gave residents a voice in the implementation of the Manchester Community Schools Project—a partnership between the Manchester Health Department, city elementary schools, philanthropists, neighborhood residents, and several nonprofit agencies—to improve and enhance educational achievement, economic well-being, access to health care services, healthy behaviors, social connectedness, safety, and living environments. A key element of this project is to make elementary schools in the Bakersville, Beech Street, and Gossler Park neighborhoods centerpieces of community life for all residents, not just those with children.
Author Justin Young reports that one-quarter of residents surveyed in 2013 in the Manchester neighborhoods of Bakersville, Beech Street, and Gossler Park say that difficulty in finding services is a major hindrance, especially to economic stability, health, and social connectedness. Focus group data suggest that the city’s foreign-born residents, especially Hispanics, have the most trouble finding and accessing services. Cost is an obstacle to accessing health care services, and older and younger focus group participants, as well as immigrants, say the cost of transportation is a barrier to accessing services. He concludes that the neighborhood in which one lives shapes a variety of outcomes related to well-being, and that a place-based approach like the community schools model can improve outcomes not only for residents of the Bakersville, Beech Street, and Gossler Park areas but for all Manchester residents
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The bark "Fritz," John R. Gossler and others, libellants, appellants, v. the Standard Sugar Refinery, claimant of cargo, etc., appellee ::brief for libellants and appellants.
No full textThe lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos
No full textThe most obvious segments of the vertebrate embryo are the trunk mesodermal somites which give rise to the segmented vertebral column and the skeletal muscles of the body. Mechanistic insights into vertebrate somitogenesis have recently been gained from observations of rhythmic expression of the avian hairy-related gene (c-hairy1) in chick presomitic mesoderm (PSM), suggesting the existence of a molecular clock linked to somite segmentation ([1]; reviewed in [2]). Here, we show that lunatic Fringe (IFng), a vertebrate homolog of the Drosophila Fringe gene, is also expressed rhythmically in PSM. The PSM expression of IFng was observed as coordinated pulses of mRNA resembling the expression of c-hairy1. We show that c-hairy1 and IFng expression in the PSM are coincident, indicating that both genes are responding to the same segmentation clock. The genes were found to differ in their regulation, however; in contrast to c-hairy1, IFng mRNA oscillations required continued protein synthesis, suggesting that IFng could be acting downstream of c-hairy1 in the clock mechanism. In Drosophila, Fringe has been shown to play a role in modulating Notch-Delta signalling [3,4], a pathway which in vertebrates has been implicated in defining somite boundaries [5-9]. These observations place the segmentation clock upstream of the Notch-Delta pathway during vertebrate somitogenesis
Konzentrationsverlauf von HCG, HPL, Prolaktin, Oestrogen und Testosteron im mütterlichen Blut nach intraamnialer und intrafetaler Injektion von DHA-S, HCG und ACTH
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