9,070 research outputs found
Investigating Ahuja-Orlin's large neighbourhood search approach for examination timetabling
No full textSince the 1960s, automated approaches to examination timetabling have been explored and a wide variety of approaches have been investigated and developed. In this paper we build upon a recently presented, sequential solution improvement technique which searches efficiently over a very large set of "adjacent" (neighbourhood) solutions. This solution search methodology, originally developed by Ahuja and Orlin, has been applied successfully in the past to a number of difficult combinatorial optimisation problems. It is based on an improvement graph representation of solution adjacency and identifies improvement moves by finding cycle exchange operations using a modified shortest path label-correcting algorithm. We have drawn upon Ahuja-Orlin's basic methodology to develop an effective automated exam timetabling technique. We have evaluated our approach against the latest methodologies in the literature on standard benchmark problems. We demonstrate that our approach produces some of the best known results on these problems
MicroRNAs in Retinal Pathophysiology and Therapeutics
No full textFollowing identification of tRNA and rRNA, the non-protein coding RNAs (ncRNAs) have been demonstrated to possess catalytic ribozyme functions (Cech et al., 1981; Guerrier-Takada et al., 1983). In recognition of the latter work, T.R. Cech and S. Altman were awarded the 1989 Noble Prize in Chemistry. Fire, et al. (1998) discovered that small double stranded RNA (ds RNA) silences the gene expression. For this observation Andre Fire and C.C. Mello earned the 2006 Nobel Prize in Physiology or Medicine. Two years later, V.R. Ambros, D.C. Baucombe, and G.B. Ruvkun were honored with the Albert Lasker Basic Medical Research Award (2008) for their contributions in the field of small RNA dependent gene regulation in plants and animals. All these findings have revolutionized the fields of gene regulation, RNA biology and brought out the possibilities of its exploitation for understanding the living processes and for use as therapeutic agents
Globale Perspektiven
No full textLeisering L, Mayer-Ahuja N, Burchardt H-J, Eckert A. Globale Perspektiven. In: Busemeyer M, Ebbinghaus B, Leibfried S, Mayer-Ahuja N, Obinger H, Pfau-Effinger B, eds. Wohlfahrtspolitik im 21. Jahrhundert. Neue Wege der Forschung. Frankfurt a.M./New York: Campus; 2013: 177-187
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Collaboration Networks, Structural Holes, And Innovation: A Longitudinal Study
No full textTo assess the effects of a firm's network of relations on innovation, this paper elaborates a theoretical framework that relates three aspects of a firm's ego network-direct ties, indirect ties, and structural holes (disconnections between a firm's partners)-to the firm's subsequent innovation output. It posits that direct and indirect ties both have a positive impact on innovation but that the impact of indirect ties is moderated by the number of a firm's direct ties. Structural holes are proposed to have both positive and negative influences on subsequent innovation. Results from a longitudinal study of firms in the international chemicals industry indicate support for the predictions on direct and indirect ties, but in the interfirm collaboration network, increasing structural holes has a negative effect on innovation. Among the implications for interorganizational network theory is that the optimal structure of interfirm networks depends on the objectives of the network members.Managemen
Portraits in neuem Rahmen Nicole Mayer-Ahuja und Oliver Nachtwey sammeln die Stimmen verkannter Leistungsträger:innen
No full textRezension von:Nicole Mayer-Ahuja / Oliver Nachtwey (2021): Verkannte Leistungsträger:innen. Berichte aus der Klassengesellschaft, Berlin: Suhrkamp. 567 S., ISBN 978-3-518-03601-3, EUR 22,00
Die Globalität unsicherer Arbeit als konzeptionelle Provokation
No full textince the 1970s, informal labor has spread from the Global South, where itwas discovered, to the Global North. In spite of what modernization theory says,informal labor has not disappeared, but is, instead, increasing worldwide. It affectsnot only employment, but also labor processes. To tackle the resulting conceptualprovocations we must explore transnational perspectives. An analysis of both inter-connected and uneven development will help debunk the notion that insecure labor isa timeless “normality”. It is important to overcome labor sociology\’s exclusive focuson a seemingly stable corporate microcosm and to question current debates on in-secure labor that ignore the impact capital has had in its development
The Forman Christian College Magazine
No full textEditorial. pp. 1-3; Dass, A. L.-Travelogue-A Trip to Chamba. pp. 3-10; Shourie, M. M.-Article-National Education and What it Stands for. pp. 10-14; Ahuja, S. L.-Essay-Economics Old and New. pp. 15-17; Satya Parkash-Efforts. pp. 17-18; Wanchoo, J. N.-Story-The Expiation. pp. 18-21; Vohra, H. R.-Essay-The Life of a Labourer. pp. 21-23; Mumtaz Hassan Ahsan-A Railway Incident. pp. 23-25; Rattan Shaw-Mr. Coward-Brave. pp. 25-27; Hostel News. pp. 27-28; Sports Notes. pp. 28-29; Chapel Talks. pp. 29-31; The Library. pp. 31-33; Vernacular Supplement [Urdu]. 14 p
Complexity of Scheduling in Synthesizing Hardware from Concurrent Action Oriented Specifications
No full textConcurrent Action Oriented Specifications (CAOS) formalism such as Bluespec Inc.'s Bluespec System Verilog (BSV) has been recently shown to be effective for hardware modeling and synthesis. This formalism offers the benefits of automatic handling of concurrency issues in highly concurrent system descriptions, and the associated synthesis algorithms have been shown to produce efficient hardware comparable to those generated from hand-written Verilog/VHDL. These benefits which are inherent in such a synthesis process also aid in faster architectural exploration. This is because CAOS allows a high-level description (above RTL) of a design in terms of atomic transactions, where each transaction corresponds to a collection of operations. Optimal scheduling of such actions in CAOS-based synthesis process is crucial in order to generate hardware that is efficient in terms of area, latency and power. In this paper, we analyze the complexity of the scheduling problems associated
with CAOS-based synthesis and discuss several heuristics for meeting
the peak power goals of designs generated from CAOS. We also discuss
approximability of these problems as appropriate
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