197 research outputs found
Intrapancreatic rupture of a splenic artery aneurysm during pregnancy – a rare case report with fetal and maternal survival
No full textJ Matern Fetal Neonatal Med. 2009 Apr;22(4):362-4.
Intrapancreatic rupture of a splenic artery aneurysm during pregnancy - a rare case report with fetal and maternal survival.
Patrelli TS, Anfuso S, Verrotti C, Fadda GM, Gramellini D, Nardelli GB.
SourceDepartment of Obstetrics, Gynecology and Neonatology, OB/GYN Unit, Parma General Hospital, University of Parma, Via Gramsci, Parma 14 43100, Italy. [email protected]
Abstract
Rupture of a splenic artery aneurysm (SAA) during pregnancy is a rare and severe condition. A 35-year-old woman at 34 weeks' gestation came to our observation for acute abdominal pain. After being diagnosed with intra-pancreatic SAA rupture, she was delivered of a live fetus by cesarean section. This is a rare case with both fetal and maternal survival
A case report of Sheehan's syndrome with acute onset,hyponatremia and severe anemia
No full textActa Biomed. 2009 Apr;80(1):73-6.
A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia.
Anfuso S, Patrelli TS, Soncini E, Chiodera P, Fadda GM, Nardelli GB.
SourceDepartment of Gynecology, Obstretrics and Neonatology, University of Parma, University Hospital of Parma, Italy. [email protected]
Abstract
Sheehan's syndrome is a well-known cause of panhypopituitarism secondary to pituitary apoplexy, that generally occurs after an intra- or postpartum bleeding episode characterized by severe hypertension or hemorrhagic shock. The diagnosis can be difficult and is often formulated after some years from the syndrome occurrence. We report the case of a woman with an early diagnosis of early-onset Sheehan's syndrome associated with severe hyponatremia following dystocic childbirth complicated by postpartum hemorrhage
Association between fetal doppler velocimetry abnormalities and confined placental trisomy 22
No full textJ Matern Fetal Neonatal Med. 2009 Jul;22(7):629-32.
Association between fetal Doppler velocimetry abnormalities and confined placental trisomy 22: A case report.
Piantelli G, Patrelli TS, Anfuso S, Neri TM, Gramellini D, Nardelli GB.
SourceDepartment of Obstetrics, Gynecology and Neonatology, University of Parma, Italy.
Abstract
The occurrence of trisomy 22 confined to the placenta is rare. We report on a patient who presented with fetal abnormal Doppler velocimetry (elevated umbilical artery pulsatility index), but serial ultrasound examinations revealed a spontaneous recovery throughout pregnancy. A healthy baby was normally delivered at 40 week
Clinical practice evaluation of combination of atosiban, ritodrine and ketoprofen for inhibiting preterm labor.
No full textMinerva Ginecol. 2007 Oct;59(5):481-9.
Clinical practice evaluation of combination of atosiban, ritodrine and ketoprofen for inhibiting preterm labor.
Grignaffini A, Soncini E, Ronzoni E, Lo Cane F, Anfuso S, Nardelli GB.
SourceDepartment of Gynaecology, Obstetrics and Neonatology, University of Parma, Parma, Italy.
Abstract
AIM: The aim of this study was to compare the efficacy and tolerability of atosiban vs ritodrine administered as single-drug or as combination therapy with the COX inhibitor ketoprofen in the treatment of preterm labor and to investigate how frequent is the need for combination therapy with ketoprofen.
METHODS: Ninety-one women with diagnosis of threatened preterm delivery at 24-33 weeks' gestation were enrolled in an observational case-control study. Forty-seven received IV atosiban (6.75 mg initial dose, 300 microg/min loading dose for 3 hours, 100 microg/min maintenance dose for 48-96 hours) and 44 IV ritodrine (0.05-0.3 mg/min). When response to the first drug in the first 2-4 hours was unsatisfactory, ketoprofen was added (100 mg loading dose IV and 100-150 mg maintenance dose every 12 hours) for a maximum of 48 hours.
RESULTS: Ketoprofen was added in 51.1% of the atosiban group and 47.7% of the ritodrine group (P 0.75, not statistically significant). The percentages of women non delivered in the two groups were 85.1% vs 81.8% at 48 hours (P=0.44) and 59.6% vs 54.5% at 7 days (P=0.39). One woman treated with atosiban reported transient dyspnea at the administration of the bolus dose; 20.5% of women who received ritodrine developed tachycardia and 4.5% dyspnea (P=0.001). Neonatal mortality and morbidity were comparable in both groups and unrelated to ketoprofen exposure.
CONCLUSION: Atosiban efficacy was comparable to ritodrine, but with a superior safety profile. A large proportion of women in both groups required second-line ketoprofen therapy, with comparable neonatal outcome
Preterm delivery and premature rupture of membranes after conization in 80 women. Preliminary data.
No full textMinerva Ginecol. 2008 Aug;60(4):295-8.
Preterm delivery and premature rupture of membranes after conization in 80 women. Preliminary data.
Patrelli TS, Anfuso S, Vandi F, Valitutto S, Migliore M, Salvati MA, De Ioris A, Condemi V, Fadda GM, Bacchi Modena A, Nardelli GB.
SourceDepartment of Obstetrics, Gynecology and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
AIM: Cervical intraepithelial neoplasia is most frequently in young women in reproductive age. Cold knife conization, laser ablation, laser conization and large loop excision are conservative methods of treatment to remove the transformation zone and preserve the cervical function. Previous studies have shown conflicting results on the outcomes of pregnancy following these therapies that might increase the risk of preterm delivery. The purpose of this study was to evaluate the outcome of pregnancy after conization and its role as predictive risk factor.
METHODS: A retrospective study was performed. The study group comprised 80 women who had a conization and that had a subsequent singleton pregnancy. Variables considered includes maternal excision date, surgery procedure, previous surgery treatments, time interval between excisional procedure and subsequent pregnancy; duration and week of pregnancy, mode of delivery, histological grading (no cervical intraepithelial neoplasia [CIN], CIN 1, CIN 2-3) and cone excised depth.
RESULTS: In group study 45 women underwent loop electrosurgical excision procedure (LEEP) conization, 32 cold knife conization and 3 laser CO2. The authors found 11 cases of cone tissue depth1 cm. Eight preterm delivery have been reported to data: 5 between 28 and 34 weeks, 2 lower than 28 weeks and 1 between 34 and 37 weeks.
CONCLUSION: In these preliminary data the percentage of preterm birth appears as 10% and in range 6-15% evaluated for women not submitted to excisional procedure
Dinoprostone: slow release vaginal insert (Propess) and intracervical gel (Prepidil) for the induction of labour with unriped cervix
No full textSecond-trimester maternal serum alpha-fetoprotein elevation and its association with adverse maternal/fetal outcome: ten years experience
No full textBACKGROUND: Alpha-fetoprotein (AFP) is the major serum protein in the embryonic stage and in the early fetal stage. The aim of this study was to determine any possible association between an "unexplained" elevation of maternal serum alpha-fetoprotein (MSAFP) levels in the second trimester of pregnancy and adverse maternal/fetal outcome.
METHODS: A retrospective cohort study, was carried out in the University of Parma, by reviewing all triple tests that had been found positive for neural tube defect screening, showing an "unexplained" MSAFP elevation (> or =2.5 multiples of the median [MoM]), which could not be ascribed to any apparent reason. These results were compared with those of negative controls (MSAFP <2.5 MoM) in order to evaluate the course and outcome of pregnancy. Statistical analysis was performed by chi-square test, Fisher's exact test, Student's t-test, and odds ratio calculation.
RESULTS: We reviewed 16,747 tests: 143 tests with high MSAFP levels were found, including 105 data already available. Out of them 21 tests were excluded from the study because of the presence of fetal malformations, chromosomal diseases, or late miscarriage. Among the 84 remaining pregnancies, 43 were significantly associated with increased rates of pregnancy pathology compared with the control group of 199 patients, with 25 complicated pregnancies. In addition, high MSAFP levels were correlated with a less favorable neonatal outcome in terms of low birth weight, Apgar score, and transfer to a neonatal intensive care unit.
CONCLUSIONS: Unexplained elevation of MSAFP levels in the second trimester of pregnancy is associated with an adverse maternal/fetal outcome, possibly suggesting the need for a more strict management of pregnancies
La gravidanza e il parto nelle donne immigrate a Parma. (2002) Atti ufficiali del Convegno “Salute e immigrazione” - Parma
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