1,013 research outputs found
Young deaf children and the computer : a study of learning styles
No full textThesis (M.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AN ROTCH.Bibliography: leaves 154-158.by Sandra S. Bellone Bleecker.M.S
Enrico Bellone, Spazio e tempo nella nuova scienza
No full textRecensione al libro di Enrico Bellone, "Spazio e tempo nella nuova scienza", che intreccia il registro storico a quello epistemologico per ripercorrere la storia e il significato delle nozioni di spazio e tempo
Diagnosis of GH deficiency in the transition period: accuracy of insulin tolerance test and insulin-like growth factor-I measurement.
No full textEur J Endocrinol. 2005 Apr;152(4):589-96.
Diagnosis of GH deficiency in the transition period: accuracy of insulin tolerance test and insulin-like growth factor-I measurement.
Maghnie M, Aimaretti G, Bellone S, Bona G, Bellone J, Baldelli R, de Sanctis C, Gargantini L, Gastaldi R, Ghizzoni L, Secco A, Tinelli C, Ghigo E.
Source
Department of Pediatrics, University of Pavia, Italy. [email protected]
Abstract
OBJECTIVE:
A consensus exists that severe growth hormone deficiency (GHD) in adults is defined by a peak GH response to insulin-induced hypoglycemia (insulin tolerance test, ITT) of less than 3 microg/l based on a cohort of subjects with a mean age of 45 years.
DESIGN AND METHODS:
By considering one of the following two criteria for the diagnosis of probable permanent GHD, i.e. the severity of GHD (suggested by the presence of multiple pituitary hormone deficiencies (MPHD)) or the magnetic resonance (MR) imaging identification of structural hypothalamic-pituitary abnormalities, 26 patients (17 males, 9 females, mean age 20.8 +/- 2.3 years, range 17-25 years) were selected for re-evaluation of the GH response to ITT and their IGF-I concentration. Eight subjects had isolated GHD (IGHD) and 18 had MPHD. Normative data for peak GH were obtained after ITT in 39 healthy subjects (mean age 21.2 +/- 4.4 years, range 15.1-30.0 years) and the reference range for IGF-I was calculated using normative data from 117 healthy individuals.
RESULTS:
Mean peak GH response to ITT was significantly lower in the 26 patients (1.8+/-2.0 microg/l, range 0.1-6.1 microg/l) compared with the 39 controls (18.5 +/- 15.5 microg/l, range 6.1-84.0 microg/l; P < 0.0001). One subject with septo-optic dysplasia had a peak GH response of 6.1 microg/l that overlapped the lowest peak GH response obtained in normal subjects. There was an overlap for IGF-I SDS between subjects with IGHD and MPHD, as well as with normal controls. The diagnostic accuracy of a peak GH response of 6.1 microg/l showed a 96% sensitivity with 100% specificity. The maximum diagnostic accuracy with IGF-I SDS was obtained with a cut-off of -1.7 SDS (sensitivity 77%, specificity 100%) while an IGF-I < or = - 2.0 SDS showed a sensitivity of 62%.
CONCLUSION:
Our data show that the cut-off value of the peak GH response to ITT of less than 3 microg/l or 5 microg/l and of IGF-I of less than -2.0 SDS are too restrictive for the diagnosis of permanent GH deficiency in the transition period. We suggest that permanent GHD could be investigated more accurately by means of an integrated analysis of clinical history, the presence of MPHD, IGF-I concentration and the MR imaging findings of structural hypothalamic-pituitary abnormalities
[Antidoto spirituale contra la peste]
No full textTit. tomado de p.9, y mención de responsabilidad tomada del final de la dedicatoria (p.8)Pie de imp. tomado de Palau, 139357Sign. : A2-A12, B-D\p12\s, E\p5\s, F, F3-F12, G\p12\s, H\p8\s, H10-H12, I\p6\sGrabados xi
A Measurement method of the ideal I-V characteristics of diodes up to the built-in voltage limit
No full textIs the persistence of isolated GH deficiency in adulthood predicted by anatomical hypothalamic-pituitary alterations?
No full textExperimental measurements of Majority and Minority Carrier Lifetime Profile in Si- epilayers by the use of an improved OCVD method
No full textIn this letter, the first experimental results of a recently proposed technique for measuring the carrier lifetime profile are presented. The technique makes use of a four-terminal bipolar test structure to electrically define the epilayer volume where recombination occurs and employs the open circuit voltage decay method for lifetime parameters extraction. For the capability of the test structure to depurate measurements from the parasitic ohmic effects, the technique is able to measure the ambipolar and minority carrier lifetime along epilayer at high and low injection levels respectively. Comparisons of measurements with numerical simulations are reported to confirm the validity of the proposed technique
Moderne metodologie per il rilievo ed il controllo dell'assetto del territorio, la valutazione d'impatto ed il monitoraggio ambientale
No full textLa presente nota si occupa dei moderni strumenti per il controllo dell'assetto del territorio, la valutazione d'impatto ed il monitoraggio ambientale. A tal fine, prende in considerazione questioni relative ai sistemi informativi territoriali ed all'elaborazione d'immagini digitali, come pure problemi d'analisi dei dati a referenza spaziale tempo-varianti e non. Un esempio reale di analisi multivariata vuole dare alla nota caratteristiche di concretezza (un sommario illustrativo sull'analisi di varianza serve da introduzione a queste importanti tecniche)
Modelling of the input I-V curves of bipolar JFET structures showing a negative resistance behaviour
No full textA Measurement Method of the Ideal I-V Characteristic of Diodes Up to the Built-in Voltage Limit
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