137 research outputs found
Comparative Evaluation of 0.1% Turmeric Mouthwash with 0.2% Chlorhexidine Gluconate in Prevention of Plaque and Gingivitis: A Clinical Study
No full textABSTRACT
Introduction
Dental plaque has been proved by extensive research to be a paramount factor in initiation and progression of gingival and periodontal diseases. Among chemical means, chlorhexidine mouthwash is regarded as the gold standard in dentistry in prevention of dental plaque. Chlorhexidine mouthwash, though effective, has certain side effects, such as brown discoloration of teeth, oral mucosal erosion, etc. Hence, there is need of an alternative medicine enmeshed within precious traditional Indian herbal therapy which is efficient, safe, and economical. Turmeric possesses anti-inflammatory, antioxidant, antimicrobial properties along with hepatoprotective, immune stimulant, antiseptic, antimutagenic properties, etc.
Objectives
This study was conducted to explore and prove the clinical efficacy of 0.1% turmeric mouthwash in mild and moderate gingivitis patients.
Materials and methods
Sixty patients with moderate gingivitis were included and divided into two equal groups: Experimental (0.1% turmeric mouthwash) and control group (0.2% chlorhexidine gluconate). The clinical parameters evaluation was done on day 0 and day 21.
Results
On intragroup comparison, statistically significant reduction in clinical parameters (plaque index, gingival index, gingival bleeding index) was seen in both groups on day 21, but on intergroup comparison, no statistically significant reduction in clinical parameters was seen on day 21 between the groups.
Conclusion
Hence, it can be concluded that 0.1% turmeric mouthwash possesses antiplaque and anti-inflammatory properties which has been proven through clinical evaluation and it was almost equally effective when compared with 0.2% chlorhexidine gluconate mouthwash in moderate gingivitis patients.
How to cite this article
Nagunuri D, Babitha GA, Prakash S. Comparative Evaluation of 0.1% Turmeric Mouthwash with 0.2% Chlorhexidine Gluconate in Prevention of Plaque and Gingivitis: A Clinical Study. CODS J Dent 2016;8(1):16-20.
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Antioxidant and hepatoprotective effects of flower extract of Millingtonia hortensis Linn. on carbon tetrachloride induced hepatotoxicity
No full textObjective: Millingtonia hortensis Linn is an abundant resource of flavonoids, which might be beneficial in protecting liver tissue from injury. The hepatoprotective and antioxidant potential of ethanolic extract of M. hortensis on carbon tetrachloride (CCl 4 ) induced hepatotoxicity and the possible mechanism involved therein were investigated in rats. Materials and Methods: Preliminary phytochemical studies were carried out to determine the total phenol and flavonoid contents. 30 adult Wistar rats were allocated into 5 groups. Control group received vehicle, group-2 received CCl 4 alone (1 ml/kg body weight, intraperitonially), groups 3 - 5 received the ethanolic flower extract in 2 dose levels (200 and 400 mg/kg) and Curcumin (100 mg/kg) as a standard for 8 days orally, followed by CCl 4 as a single dose on the 8 th day. 48 hours later, blood was withdrawn, serum was subjected to biochemical assessments, and liver homogenate was examined for lipid peroxides, glutathione, superoxide dismutase, catalase and total protein levels. Furthermore, hepatic tissues were subjected to histopatological studies. Results: CCl 4 treatment produced a profound increase in the levels of malondialdehyde, hepatic marker enzymes and bilirubin content compared with the control (P < 0.05). Pre-treatment with the flower extract of M. hortensis significantly enhanced the levels of endogenous antioxidants and reduced the levels of hepatic marker enzymes in relation to the CCl 4 treated group (P < 0.05). Balloning degeneration and fatty changes in hepatocytes was prevented by pre-treatment with the flower extract. Conclusion: The antioxidant nature of the flower extract of M. hortensis could be responsible for averting damage to the liver
A clinical study of feto-maternal outcome in pregnancies with oligohydramnios
No full textBackground: The amniotic fluid that surrounds the fetus serves several roles during pregnancy. Oligohydramnios is diagnosed when ultrasonographically the AFI is less than 5cm/5th percentile. It affects 3-5% of all pregnancies. Assessment of amniotic fluid volume is a helpful tool in determining who is at risk for potentially adverse obstetric and perinatal outcome.Methods: Pregnant women with oligohydramnios reporting to Cheluvamba Hospital, attached to Mysore Medical College and Research Institute, Mysore from December 2012- June 2014 were included in the clinical study of maternal and fetal outcome. All singleton, non-anomalous, low risk pregnancies with AFI≤5cm with intact membranes and gestational age between 28-42 weeks were included in the study. Various outcomes such as mode of delivery, meconium staining, Apgar at 1 and 5 minutes, birth weight and NICU admissions were assessed.Results: A total of 130 cases of isolated oligohydramnios were assessed. 55.4% had vaginal delivery. 13.8% underwent elective LSCS and 30.8% had emergency LSCS. 18.5% had meconium stained liquor, 4.6% babies had APGAR of <7 at 5 minutes. 17.7% had birth weight of <2.5 kg and 6.9% of babies required NICU admission.Conclusions: The present study was conducted to know the feto-maternal outcome in pregnancies with oligohydramnios. The study showed that isolated oligohydramnios had no adverse maternal or perinatal outcome.</jats:p
Differential induction of Superoxide Dismutase in Downy Mildew-resistant and Susceptible Genotypes of Pearl Millet
No full textDifferential induction of superoxide dismutase (SOD) in downy mildew-resistant and -susceptible genotypes of pearl
millet (
Pennisetum glaucum
) was observed on inoculation with
Sclerospora graminicola
. SOD activity was studied in
resistant (IP18292) and susceptible (23B) pearl millet seedlings inoculated with
S. graminicola
. SOD activity increased by
2·3-fold in resistant seedlings upon inoculation. SOD activity was greatest in roots, with a specific activity of 3182 U per mg
protein, after inoculation. SOD activity increased in all the resistant genotypes upon inoculation with
S. graminicola
.
Native PAGE analysis showed four isozymes of SOD, three of which (SOD-1, -2 and -4) were Cu/Zn-SOD, whereas
isozyme SOD-3 was Mn-SOD. This study also revealed increased intensity of all four isozymes of SOD in the resistant
genotype upon inoculation. The involvement of SOD in pearl millet (host)–downy mildew pathogen interaction is
discussed
"What's this country coming to?": Patrick McCabe's Bog Gothic in The Butcher Boy
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Inglês: Estudos Linguísticos e Literários, Florianópolis, 2020.Este estudo analisa a construção do ?Gótico do Pântano? no romance The Butcher Boy, escrito pelo autor irlandês Patrick McCabe e publicado pela primeira vez em 1992. Ao analisar o uso de elementos do Gótico Clássico e do Novo Gótico Americano, assim como a sociedade irlandesa na metade do século XX no romance, meu objetivo principal é descobrir o que constitui o subgênero literário do Gótico do Pântano, sendo o autor supracitado considerado o criador de tal estilo. Minha hipótese é que o Gótico do Pântano se dá pela mistura de elementos do Gótico Clássico e do estilo literário voltado à psique do Novo Gótico Americano situados em uma Irlanda rural que sofre com problemas sociais, como uma maneira revisionista de representar a disparidade entre as ?Irlandas? rurais e industrializadas. Para melhor entender se o Gótico do Pântano é assim construído, este estudo apresenta uma contextualização história da Irlanda e do gênero Gótico no país, assim como o termo Gótico do Pântano foi criado e estudado até agora. No que tange o aporte teórico, a análise está embasada no conceito de Gótico Clássico, se baseando nos conceitos de Siobhán Kilfeather, George O?Brien e Edmund Burke; nas ideias de Novo Gótico Americano de David Punter, Irving Malin e Babitha B.; e nos trabalhos sobre nacionalismo de Terrence Brown e Yen-Chi Wu. Argumento que, ao apresentar um romance que foca nas questões psicológicas do narrador, enquanto usa elementos comumente relacionados ao Gótico Clássico num contexto de uma era instável na Irlanda, Patrick McCabe cria seu próprio estilo de Gótico em The Butcher Boy, o qual será reproduzido em seus trabalhos posteriores.Abstract : The present study analyses the construction of Bog Gothic in the The Butcher Boy, novel written by the Irish author Patrick McCabe and first published in 1992. By analysing the use of Classic Gothic and New American Gothic tropes, as well as Irish society in the mid- twentieth century in the novel, my main point is to find out what constitutes the literary subgenre Bog Gothic, the aforementioned author being regarded as the creator of such style. My hypothesis is that the Bog Gothic is made up from a mixture of Classic Gothic elements and New American Gothic?s psyche-oriented writing style placed in a rural Ireland that suffered from social problems, from a revisionist point of view, to present the country?s disparity between rural and industrialised Ireland. As a means of better understanding if this is how Bog Gothic is constructed, this study offers a historical contextualization of Ireland and the Gothic genre in the country as well as how the term Bog Gothic was created and has been treated so far. Concerning the theoretical background, the analysis is based on the concept of Classic Gothic, relying on Siobhán Kilfeather?s, George O?Brien?s and Edmund Burke?s concepts of Gothic; David Punter?s, Irving Malin?s and Babitha?s insights on New American Gothic; and Terrence Brown?s and Yen-Chi Wu?s work on nationalism. I argue that, by presenting a novel that focuses on the narrator?s psychological issues at the same time that it uses tropes usually featured in Classic Gothic novels, within the Irish context of an unstable era, Patrick McCabe creates his own style of Gothic in The Butcher Boy, which will be replicated on later works by him
Differential induction of superoxide dismutase in downy mildew-resistant and -susceptible genotypes of pearl millet
No full textDifferential induction of superoxide dismutase (SOD) in downy mildew-resistant and -susceptible genotypes of pearl millet (Pennisetum glaucum) was observed on inoculation with Sclerospora graminicola. SOD activity was studied in resistant (IP18292) and susceptible (23B) pearl millet seedlings inoculated with S. graminicola. SOD activity increased by 2·3-fold in resistant seedlings upon inoculation. SOD activity was greatest in roots, with a specific activity of 3182 U per mg protein, after inoculation. SOD activity increased in all the resistant genotypes upon inoculation with S. graminicola. Native PAGE analysis showed four isozymes of SOD, three of which (SOD-1, -2 and -4) were Cu/Zn-SOD, whereas isozyme SOD-3 was Mn-SOD. This study also revealed increased intensity of all four isozymes of SOD in the resistant genotype upon inoculation. The involvement of SOD in pearl millet (host)–downy mildew pathogen interaction is discussed
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