6,087 research outputs found
A Life Below with Joe Sulentic, Deadwood SD, Lawrence County
No full text4 x 5 b/w photograph, man examining a rock wallChinese Authority - Joe Sulentic, author of a book on the Chinese in Deadwood, points out a bit of history in the tunnels that run below Deadwood's streets. The Chinese came to Deadwood in the 1800's. SD Tourism Phot
Efficacy and tolerability of bilateral sustained-release dexamethasone intravitreal implants for the treatment of noninfectious posterior uveitis and macular edema secondary to retinal vein occlusion
No full textSteven J Ryder,1 Danilo Iannetta,1 Swetangi D Bhaleeya,2 Szilárd Kiss1 1Department of Ophthalmology, Weill Cornell Medical College, New York, NY, USA; 2Department of Ophthalmology, University of South Florida, Tampa, FL, USA Purpose: To report our experience with bilateral placement of dexamethasone 0.7 mg (DEX) sustained-release intravitreal implant in the management of noninfectious posterior uveitis or macular edema secondary to retinal vein occlusion.Methods: A retrospective chart review of patients with bilateral noninfectious posterior uveitis and macular edema secondary to retinal vein occlusion who were treated with DEX intravitreal implant was performed. Ocular side effects such as intraocular pressure (IOP), cataract, and tolerability of bilateral injections was reviewed.Results: Twenty-two eyes of eleven patients treated with a total of 32 DEX implants were included. Ten of eleven patients received bilateral implants due to active noninfectious uveitis while the other demonstrated macular edema in both eyes following separate central retinal vein occlusions. Among the patients with bilateral uveitis, the mean interval between DEX implant in the initial eye and the subsequent DEX in the fellow eye was 15.6 days (range 2–71 days). Seven of the ten patients received the second implant in the fellow eye within 8 days of the initial implantation. None of the patients had bilateral implantations on the same day. Seven eyes required reimplantation for recurrence of inflammation (mean interval between first and repeat implantation was 6.00±2.39 months). Following single or, in the case of the aforementioned seven eyes, repeat DEX implantation, all 20 uveitic eyes demonstrated clinical and/or angiographic evidence of decreased inflammation in the form of reduction in vitreous cells on slit lamp ophthalmoscopy, macular edema on ophthalmoscopy, or optical coherence tomography and/or disc and vascular leakage on fluorescein angiography. The mean follow-up for all eyes after initial implantation was 23.57 months (range 1–48 months). IOP was significantly higher (P=0.028) at 6 months (16.62 mmHg ±5.97) but not (P=0.82) at most recent follow-up (14.9±3.37 mmHg) when compared with baseline (14.68±3.02 mmHg). Four eyes (18.2%) required initiation of IOP-lowering medications. During the follow-up period, no eyes underwent filtration or cataract extraction. No serious ocular adverse effects were noted during the follow-up period.Conclusion: In patients with bilateral noninfectious posterior uveitis and macular edema secondary to vein occlusion, bilateral injection of DEX intravitreal implant was well tolerated and had an acceptable safety profile. Keywords: bilateral uveitis, dexamethasone implant, Ozurdex 
Front Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, leafless trees in front of a two-story house with a bay window and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
High diagnostic yield of tuberculosis from screening urine samples from HIV-infected patients with advanced immunodeficiency using the Xpert MTB/RIF assay.
No full text: ABSTRACT:: We determined the diagnostic yield of the Xpert MTB/RIF assay for tuberculosis (TB) when testing small volumes of urine from ambulatory HIV-infected patients prior to starting antiretroviral therapy (ART) in South Africa. Compared to a gold standard of sputum culture, the sensitivity of urine Xpert among those with CD4 cell counts of <50, 50-100 and >100 cells/?L were 44.4%, 25.0% and 2.7% (P=0.001), respectively. Urine Xpert testing provides a means of rapid TB diagnosis in patients with advanced immunodeficiency and poor prognosis. These data are indicative of high rates of TB dissemination and renal involvement in this clinical population
Rear and Side Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, a two-story house with a bay window and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
Front and Side Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, leafless deciduous trees in front of a two-story house with a single-story addition and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
Fort Sully Hospital, Sully County
No full text7 x 5 photograph, two people in front of a two-story building with dormers and a covered wrap-around porch surrounded by a post and wire fenceFort Sully P97 [stamp] Property of: South Dakota State Historical Society Pierre, South Dakota [stamp] Give photo credit to: South Dakota State Historical Society. Ft. Sully (Hospital in 1951) As it stood on the farm of Paul Steffen in Llewellyn Park Tsp., Sully County. Photo in collection of Bessie B. Lumley, Oneida, SD. Copied from the thesie, History of Ft. Sully (underlined) by Steven Hoekman, Univ, of S.D. Photo cred-it must be acquired from author or Univ. of S.D. (underlined) A
Screening for hepatocellular carcinoma: patient selection and perspectives
No full textWaleed Fateen, Stephen D Ryder NIHR Biomedical Research Unit in Gastrointestinal and Liver Diseases, Nottingham University Hospitals NHS Trust, The University of Nottingham, Nottingham, UK Abstract: Hepatocellular carcinoma (HCC) develops on the background of liver cirrhosis often from multiple, simultaneous factors. The diagnosis of a single small HCC comes with good prognosis and provides a potential for cure. In contrast, the diagnosis of multifocal, large HCC has high mortality and poor prognosis. Unfortunately, the majority of HCC is diagnosed at such late stages. A surveillance program endorsed by regional liver societies involves six-monthly ultrasound surveillance of at-risk patients. This had been in action for the last two decades. It has led to marked increase in the proportion of patients presenting with small unifocal nodules found on surveillance. The development of tools to enhance our ability in optimizing available surveillance is likely to improve the prognosis of patients with HCC. In this review, we discuss the difficulties in utilizing HCC surveillance and possible means of improvement. Keywords: hepatocellular carcinoma, surveillance, screening, risk stratification 
Jumping sustainability meme; SD transfer from society to universities
No full textSince the 1972 Stockholm Conference, many Sustainable Development declarations, charters, and partnerships have been developed, both in the overall societal context and within higher education frameworks. This paper addresses two issues: (1) a comparison of the development of sustainable development initiatives in society and in universities and (2) an analysis of how those initiatives are influencing educational institutions? SD activities. The analysis indicates that SD needs to be incorporated in a transdisciplinary manner throughout: curricula, research, operations, outreach and engagement with stakeholders, collaboration with other universities, assessment and reporting, institutional framework, on-campus life experiences, and educate the educators programmes. These key elements must be integrated systemically in the HEIs in order to provide learning and career value to those participating in the SD transition. One of the key observations is that the concept of \u84meme? diffusion/transfer from the diverse declarations, charters and partnerships is slow and inefficient. The question is why is it so slow and ineffective and what can be done to speed it up throughout society? The authors propose the following ways to speed up the transfer, and implementation of the SD in higher education \u84meme?: universities and their leaders should become more proactive in engaging with SD, SD should be made the \u84Golden Thread? throughout the university system, and recognise those engaged with SD and foster multiplier effect
How UV photolysis accelerates the biodegradation and mineralization of sulfadiazine (SD)
No full textabstract: Sulfadiazine (SD), one of broad-spectrum antibiotics, exhibits limited biodegradation in wastewater treatment due to its chemical structure, which requires initial mono-oxygenation reactions to initiate its biodegradation. Intimately coupling UV photolysis with biodegradation, realized with the internal loop photobiodegradation reactor, accelerated SD biodegradation and mineralization by 35 and 71 %, respectively. The main organic products from photolysis were 2-aminopyrimidine (2-AP), p-aminobenzenesulfonic acid (ABS), and aniline (An), and an SD-photolysis pathway could be identified using C, N, and S balances. Adding An or ABS (but not 2-AP) into the SD solution during biodegradation experiments (no UV photolysis) gave SD removal and mineralization rates similar to intimately coupled photolysis and biodegradation. An SD biodegradation pathway, based on a diverse set of the experimental results, explains how the mineralization of ABS and An (but not 2-AP) provided internal electron carriers that accelerated the initial mono-oxygenation reactions of SD biodegradation. Thus, multiple lines of evidence support that the mechanism by which intimately coupled photolysis and biodegradation accelerated SD removal and mineralization was through producing co-substrates whose oxidation produced electron equivalents that stimulated the initial mono-oxygenation reactions for SD biodegradation.This is the authors' final accepted manuscript. The final publication is available at http://dx.doi.org/10.1007/s10532-014-9711-
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