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A review of methodology for sample size calculations in cluster randomised trials.
PMCID: PMC3287737This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.PMCID: PMC3287737PMCID: PMC3287737PMCID: PMC3287737PMCID: PMC3287737PMCID: PMC3287737PMCID: PMC328773
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A study of John Clare in his historical and political context
As the title indicates, the basis of the thesis is to set John Clare’s life and work within the context of the social and political history of his time. It is a study that is long overdue. The manner in which topical and political matters were mediated to him and were reflected in his work are analysed. His introduction to the literary and social worlds of Stamford and London is evaluated, and the advantages and disadvantages of patronage assessed. The active and complex political culture of Stamford has been taken into account as this may have affected his later political statements and a growing awareness of his audience. His antagonism to enclosure and the social changes that it engendered are considered. Three major questions that arise from this are addressed. The two local newspapers that Clare is known to have read are used throughout. His correspondence with friends, colleagues and casual correspondents has provided valuable insights as have his poetry and prose writings. Research in the Northamptonshire Record Office has revealed important new information in the form of one book of Enclosure Commissioners’ Minutes dated 1809-14, the first five years of the enclosure of Helpstone, Clare’s native village
Progress and Distress on the Stratford Estate in Clare during the Eighteen Forties
In the late 1980s and early 1990s, the author acquired about 30,000 letters written mainly in the 1840s. These pertained to estates throughout Ireland managed by James Robert Stewart and Joseph Kincaid, hereafter denoted SK. Until the letters - called the SK correspondence in what follows - became the author’s property, they had not seen light of day since the 1840s. Addressed mainly to the SK office in Dublin, they were written mainly by landlords, tenants, the partners in SK, local agents, etc. After about 200 years in operation as a land agency, the firm in which members of the Stewart family were the principal partners - Messrs J. R. Stewart & Son(s) from the mid-1880s onwards -- ceased business in the mid-1980s. Since 1994 the author has been researching the SK correspondence of the 1840s. It gives many new insights into economic and social conditions in Ireland during the decade of the great famine, and into the operation of Ireland’s most important land agency during those years. It is intended ultimately to publish details on several of the estates managed by SK in book form. The proposed title is Landlords, Tenants, Famine: Business of an Irish Land Agency in the 1840s, a draft of which has now been completed. A majority of the letters in the larger study from which the present article is drawn are on themes some of which one might expect - rents, distraint (seizure of assets in lieu of rent) ; ‘voluntary’ surrender of land in return for ‘compensation’ upon peacefully quitting; formal ejectment (a matter of last resort on estates managed by SK); landlord-assisted emigration (on a scale much more extensive than most historians of Ireland in the 1840s appear to believe); petitions from tenants; complaints by tenants, both about other tenants and local agents; major works of improvement (on almost all of the estates managed by SK); applications by SK, on behalf of proprietors, for government loans to finance improvements; recommendations of agricultural advisers hired by SK, ete. Thus, most of the SK correspondence is about aspects of estate management. It seems, in the 1840s, that the only estate in Clare managed by SK was that of the elderly Col. Stratford. Although the files on the relatively small Stratford estate are much less extensive than those on some of the estates investigated in detail in the draft of Landlords, Tenants, Famine, they do refer to most of the core aspects of estate management mentioned above. But in the case of the Clare estate, the material on some of those themes is extremely thin.
Author interview: considering Emma Goldman with Professor Clare Hemmings
We speak to Professor Clare Hemmings about her new book, Considering Emma Goldman: Feminist Political Ambivalence and the Imaginative Archive (Duke UP, 2018), which examines Goldman’s significance as an anarchist activist and thinker to the past and present of feminist theories and activism. Hemmings shows that the contradictions and tensions within Goldman’s approach to race, gender and sexuality speak to unresolved questions that continue to shape feminist practices and politics today
Why feminist stories matter: Katy Deepwell interviews Clare Hemmings
Clare Hemmings is Professor of Feminist Theory and Director of the Gender Institute at the London School of Economics. She is the author of Why Stories Matter: The Political Grammar of Feminist Theory (Duke University Press, 2011). For this volume, Katy Deepwell interviewed her about her views on feminist historiography and feminist theory, which Hemmings has defined in terms of three dominant narratives about the direction of feminism’s past, present and future
The life and works of Osbert of Clare
Osbert of Clare was an English monastic writer, whose works extended from
the mid-1120s to the mid-1150s. His Latin hagiography reflects a deep admiration for
Anglo-Saxon saints and spirituality, while his letters provide a personal perspective
on his turbulent career. As prior of Westminster Abbey, Osbert of Clare worked to
strengthen the rights and prestige of his monastery. His production of forged or
altered charters makes him one of England's most prolific medieval forgers. At times
his passion for reform put him at odds with his abbots, and he was sent into exile
under both Abbot Herbert (1121-c.1136) and Abbot Gervase (1138-c.1157). Also
Osbert, as one of the first proponents of the Immaculate Conception of Mary, wrote
about the feast, worked to legitimize its celebration, and provided us with the only
significant narration of its introduction to England.
This thesis is divided into two sections. The first section is principally
historical and the second is principally literary. In the first section, I provide an
overview of Osbert of Clare's career and examine in greater detail two of his most
significant undertaking: his promotion of Westminster Abbey and his attempted
canonization of Edward the Confessor. In the second section, I give a philological
study of Osbert Latin style and examine themes that nm throughout his writings, such
as virginity, exile and kingship. Osbert's promotion of the feast of the Immaculate
Conception is included in the second section of the thesis because of its ties to the
themes of virginity and femininity within his writings. There are also two appendices:
the first is a survey of the extant manuscripts of Osbert's writings, and the second is
an edition of Osbert's unpublished Life of St Ethelbert from Gotha,
Forschungsbibliothek MS Memb. i. 8l
Observations on the nature and cure of abscesses, [electronic resource] : and of wounds in general; with a particular account of the art of healing, and the great utility of medical surgery. Chiefly Selected from Authors who have written on this important Subject. By Peter Clare, Surgeon.
The second 24pp. section contains 'Observations upon the origin and art of surgery in general';the last few paged and unpaged leaves contain letters to Peter Clare on surgical matters.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
Maternal selenium status in pregnancy, offspring glutathione peroxidase 4 genotype, and childhood asthma
Effectiveness of structured patient-clinician communication with a solution focused approach (DIALOG+) in community treatment of patients with psychosis - a cluster randomised controlled trial
BackgroundLarge numbers of patients with psychosis have regular meetings with key clinicians in the community. There is little evidence on how these meetings should be conducted to be therapeutically effective. DIALOG, a computer mediated procedure, was shown to improve outcomes in a European multi-centre trial. DIALOG structures the patient-clinician communication and makes it patient-centred, but does not guide clinicians as to how to respond to patients’ concerns. DIALOG has been further developed into DIALOG+, which uses advanced software and, additionally, provides a four step approach - based on a solution focused model - for addressing patients’ concerns. We designed a cluster randomised controlled trial to test the effectiveness of DIALOG+ in improving treatment outcomes of patients with psychosis in the community.Methods/designKey workers are recruited from community mental health teams in East London and randomly allocated to either the intervention or control group. Out of their case loads, we identify patients with schizophrenia (F 20–29) and a moderate or lower level of subjective quality of life (MANSA score <5), who are treated according to the allocation of their key workers. Key workers in the intervention group are trained in using DIALOG+ and use it with each patient over a six-month period. Control patients rate their satisfaction with life and treatment on a tablet to control for the effect of regular ratings and the use of modern technology. We are recruiting up to 42 key workers to reach a total sample size of 180 patients. Clinical and social outcomes including costs are assessed after 3, 6 and 12 months. Primary outcome is subjective quality-of-life at 6 months.DiscussionThe trial aims to evaluate the effectiveness of a novel intervention (DIALOG+) which uses modern technology to support routine patient-clinician meetings in community care, makes the communication patient centred and guides patients and clinicians to address concerns. DIALOG+ is a generic and widely applicable intervention. If shown as effective, it can be used to improve outcomes of community care on a large scale, ensuring that routine encounters are therapeutically effective. DIALOG+ can also be implemented across services at relatively low additional costs
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