1,721,103 research outputs found
Competing power differentials in ethnographic writing:considerations when working with children and young people
No full textIntroduction
No full textThe origins and key debates regarding institutional ethnography (IE) are briefly outlined. Key questions regarding what is IE and how can it be better critically understood and applied are addressed, before a summary of each contributing chapter is summarized. IE is relevant and has a growing following, yet its distinct ontological, epistemological, methodological, and theoretical nature must be acknowledged and appropriately grounded within firm historical roots in order to clearly interrogate its contemporary developments
New IGH@ partners in B-cell precursor acute lymphoblastic leukaemia
No full textNovel and recurrent translocations affecting multiple chromosomes were highlighted with refined FISH mapping identifying putative IGH@ partner genes at, or flanking, the translocation breakpoints. Cytogenetics, metaphase and interphase FISH, using a dual colour break-apart probe specific for IGH@, identified seventeen translocations, seven of which were recurrent. Sequential FISH mapping of four translocations, t(14;19)(q32;q13), t(8;14)(q11;q32), previously reported, and novel translocations, t(14;14)(q11;q32)/inv(14)(q11q32) and t(14;20)(q32;q13) identified the involvement of five members of the same gene family, CAATT enhancer binding protein (CEBP). Long distance inverse PCR (LDI-PCR) with primers specific for the IGHJ6 gene segment allowed molecular cloning and further evidence to confirm the involvement of genes CEBPA (19q13, n=11), CEBPG (n=1), CEBPD (uq11, n=10), CEBPE (14q11, n=4) and CEBPB (20q13, n=4). Over-expression of the respective target genes was shown by qRT-PCR in those with available material. The same techniques were applied to the translocation, t(6;14)(p22;q32), previously reported in a single case of B-cell ALL, confirming the recurrent nature of this translocation and the partner gene as inhibitor of DNA binding 4 (Id4). Similarly, CRLF2 was implicated in both translocations, t(X;14)(p22;q32) and t(Y;14)(p11;q32). Another four partner genes to the IGH@ locus were identified: TCRγ(7p14), MILLT10 (10p14), BRCC2 (11q24) and IGF2BP1 (17q21). This study has led to the identification of multiple partners of the IGH@ locus in BCP-ALL patients, which were previously unknown. Understanding the function of these genes in the lymphoid cell lineage may define a new subgroup of BCP-ALL in which specific drug development may improve outcome.</p
Is This Ethical? Using This Question as a Starting Point
No full textThis chapter outlines the history of ethical regulation and considers how the position of ethics has shifted. The intent of this book is to explore novice and accomplished ethnographers ‘everyday, real-life’ ethical challenges and considerations against a backdrop of theoretical and ethical guideline scrutiny
Managing Ethics When Working with Young People and Children
No full textAll research has the potential to affect people, ethnographers delve into the life of the every day of their participants, they walk their walk, talk their talk and strive for valid, in-depth contextualised data, gathered over a longitudinal and often intimate basis. Ethnography is explorative and inductive. It is messy, unpredictable and complex. Ethnography conducted with young people and children adds to the intricacy of managing ethically sound research practice within and beyond the field. In recent years, ethnographies with children, young people and families have become increasingly prominent, yet few scholars have written about conducting ethnographic research with children and young people (Albon & Barley, 2021; Levey, 2009; Mayeza, 2017). The ethnographer that works with children and young people needs to be aware that the power relationship between adults and children operates in complex and sometimes surprising ways and so needs to be ethically aware, ethically reactive and be prepared to be ethically challenged
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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