1,720,993 research outputs found
Perdarahan Uterus Abnormal (PUA) di Rumah Sakit Umum Pusat Haji Adam Malik Medan Tahun 2020-2021
No full textBackground. Abnormal uterine bleeding (AUB) is one of the most common gynecological conditions in women of reproductive age. AUB is described as menstrual complaints in terms of regularity, frequency, duration, volume and occurs outside of pregnancy. Aim. To identify how the incidence of Abnormal Uterine Bleeding (AUB) at the RSUP H. Adam Malik Medan in 2020-2021. Method. This research is a descriptive study with a cross sectional design. Sampling was taken using total sampling and using retrospective data in the form of medical records with a diagnosis of AUB at RSUP H. Adam Malik Medan in 2020-2021. Results. There were 197 cases of AUB with the highest distribution in the age group of 41-50 years with 84 people (42.6%). The most cases of AUB with obese BMI were 91 people (46.2%), married status as many as 176 people (89.3%), had the last education level of senior high school as many as 99 people (50.3%), 144 people (73.1%) got their first menstruation when they were >12 years old, 80 people (40.6%) had multipara parity, 90 people (45.7%) received medical therapy. Based on the PALM-COEIN classification, the most AUB cases were AUB-L with 99 people (50.3%). Based on the classification of AUB-L locations, most locations were submucosa with 38.6%. Conclusion. Based on the research, it was found that AUB-L cases were still the most common cases at the RSUP H. Adam Malik Medan in 2020-2021.115 HalamanSkripsi Sarjan
Pengaruh Promosi Kesehatan Terhadap Pengetahuan, Sikap dan Tindakan Siswa Wanita di SMA An-Nizam Medan Tentang Endometriosis
No full textLatar Belakang. Endometriosis merupakan sebuah kelainan ginekologis yang sering ditandai dengan dismenore, dispareuni dan atau infertilitas. Gejala ini tidak khas dan sering muncul pada keadaan lain termasuk yang fisiologis sehingga sering diabaikan. Angka kejadian pada kasus ini cukup tinggi terutama pada usia reproduktif. Penyakitnya yang cenderung asimtomatis membuat endometriosis terlambat didiagnosis hingga kurang lebih tujuh tahun sejak awitan. Pemeriksaan non-invasif dan laboratorium sederhana yang spesifik belum ditemukan sehingga penanganan dengan pilihan terapi apapun belum tentu menyelesaikan masalah secara tuntas. Oleh karena itu, endometriosis lebih baik dicegah sebelum diderita. Namun sayangnya, pengetahuan tentang endometriosis masih sangat minim sehingga masyarakat tidak mengintervensi apapun untuk mencegah keadaan ini. Promosi kesehatan yang merupakan pendidikan dan modifikasi lingkungan masyarakat diharapkan bisa membentuk persepsi baru tentang konsep sehat-sakit sehingga memengaruhi sikap dan tindakan pencegahan untuk mengurangi angka kejadian dan meningkatkan kualitas kesehatan. Tujuan. Secara umum, penelitian ini bertujuan untuk mengetahui pengaruh promosi kesehatan terhadap pengetahuan, sikap dan tindakan para wanita tentang endometriosis di SMA An-Nizam Medan. Metode. Penelitian ini menggunakan quasi-experimental design dengan metode one group pretest-posttest. Data primer diperoleh dengan teknik angket menggunakan kuesioner, dilakukan pengukuran sebelum dan sesudah promosi kesehatan. Penarikan sampel menggunakan total sampling sebanyak 102 orang. Analisis data menggunakan Wilcoxon signed rank test. Hasil. Berdasarkan hasil analisis data didapatkan peningkatan pada pengetahuan, sikap dan tindakan sebelum dan sesudah promosi kesehatan. Nilai p ketiga variabel adalah 0,001 atau p < 0,05 yang menyatakan adanya perbedaan yang signifikan. Kesimpulan. Promosi kesehatan dapat meningkatkan nilai pengetahuan, sikap dan tindakan terkait endometriosis sebagai upaya menurunkan angka kejadian.Background. Endometriosis is a gynecological disorder that is often characterized by dysmenorrhea, dyspareunia and or infertility. The symptoms are not typical and often appear in other circumstances including physiological ones so often ignored. The incidence in this case is quite high, especially in the reproductive age. The disease which tends to be asymptomatic makes endometriosis often diagnosed too late until about seven years since onset. Specific non-invasive tests and simple laboratory tests have not been found, so that treatment with any treatment option does not necessarily resolve the problem completely. Therefore, endometriosis is better prevented before it suffers. But unfortunately, knowledge about endometriosis is still very minimal so people do nothing to prevent this condition. Health promotion ehich is an education and modification of the community environment is expected to form new perceptions of health-illness concept so as to influence attitudes and preventive behaviour to reduce the incidence and improve the quality of health. Objective. To determine the effect of health promotion on the knowledge, attitude and action of female students about endometriosis in SMA An-Nizam Medan. Method. This study uses quasi-experimental design with the one group pretest-posttest method. Primary data obtained by questionnaires, measurements taken before and after health promotion. The number of samples was 102 students, using total sampling. Data analysis using Wilcoxon signed rank test. Result. Based on the results od data analysis, we found an increase in the score of knowledge, attitudes and actions before and after health promotion. The p value of the three variables is 0,001 or p < 0,05 which indicates a significant difference. Conclusion. Health promotion can increase the value of knowledge, attitudes and actions related to endometriosis as an effort to reduce the incidence rate.Skripsi Sarjan
Hubungan Obesitas dengan Kejadian Mioma Uteri di Rumah Sakit Umum Pusat Haji Adam Malik Medan Tahun 2016
No full textBackground. Uterine fibroids are the most common benign tumors of the reproductive organs that
develop in women of reproductive age. Obesity is considered as one of the risk factors of uterine
fibroids. Correlation between obesity and uterine fibroids shows inconsistent results in several
studies. Objectives. The purpose of this study is to see the relation between obesity and uterine
fibroids in Haji Adam Malik General Hospital in 2016. Methods. This study is an analytical
descriptive study with case control design. The samples were subjects of medical records in Haji
Adam Malik General Hospital in 2016 that had met the inclusion and exclusion criteria and were
divided into groups of cases and controls (100 subjects for case and 100 subjects for control). For
case, the patients of uterine fibroids were used and for the controls, non-uterine fibroids patients
were used. The technique used for collecting the data was consecutive sampling. Results. Out of
200 samples, there were 43 obese patients with uterine fibroids in 2016. Based on the number of
cases related to age range, cases of obesity with uterine fibroids were found the most in the age
range of 41-50 years old which were 25 cases (58,1%). Based on number of parity, cases of
obesity with uterine fibroids were found the most in nulliparous women which were as many as 16
cases (37,2%). The results of chi square analysis showed that there was a relationship between
obesity and uterine fibroids (p = 0,001, OR = 2,838, CI = 95%) with obese patients had a
tendency of 2,838 times more likely to develop uterine fibroids compared with patients who were
not obese. Conclusion. There was a significant correlation between obesity and uterine fibroids.Latar Belakang. Mioma uteri merupakan tumor jinak organ reproduksi yang paling umum terjadi
pada wanita usia reproduktif. Obesitas dianggap sebagai salah satu faktor risiko terjadinya
mioma uteri. Hubungan antara obesitas dengan mioma uteri masih menunjukkan hasil yang tidak
konsisten pada berbagai literatur. Tujuan. Penelitian ini dilakukan untuk melihat hubungan
antara obesitas dengan mioma uteri di RSUP HAM tahun 2016. Metode. Penelitian yang
dilakukan bersifat analitik deskriptif dengan desain case control. Sampel penelitian adalah subjek
dari data rekam medis di RSUP Haji Adam Malik pada tahun 2016 yang telah memenuhi kriteria
inklusi dan eksklusi dan dibagi menjadi kelompok kasus dan kontrol (100 sampel untuk kasus dan
100 sampel untuk kontrol). Untuk kasus, data yang digunakan adalah pasien mioma uteri dan
untuk kontrol adalah pasien non-mioma uteri. Teknik pengambilan data adalah secara
consecutive sampling. Hasil. Dari 200 sampel, didapatkan 43 pasien yang mengalami obesitas
dengan mioma uteri selama tahun 2016. Berdasarkan angka kejadian sesuai rentang usia, kasus
obesitas dengan mioma uteri ditemukan paling banyak pada kelompok 41-50 tahun yaitu 25 kasus
(58,1%). Berdasarkan jumlah paritas, kasus obesitas dengan mioma uteri paling banyak
ditemukan pada kelompok nullipara yaitu 16 kasus (37,2%). Hasil uji Chi square menunjukkan
ada hubungan antara obesitas dengan kejadian mioma uteri (p=0,001, OR=2,838, CI=95%)
dengan penderita obesitas 2,838 kali lebih berisiko menderita mioma uteri daripada orang yang
tidak obesitas. Kesimpulan. Ada hubungan yang bermakna antara obesitas dengan kejadian
mioma uteriSkripsi Sarjan
Analisis Faktor Risiko terhadap Angka Kejadian Sindrom Pramenstruasi pada Mahasiswi Fakultas Kedokteran Universitas Sumatera Utara Angkatan 2020 -2022
No full textBackground
. Every normal woman undergoes the menstrual cycle, during which
hormonal changes often lead to issues such as premenstrual syndrome (PMS). The
exact cause of PMS is not yet known; however, it is frequently associated with
unhealthy lifestyles commonly exp erienced by medical students, including poor
sleep quality, low physical activity, and high stress levels. Objective . To determine
the relationship between BMI, sleep quality, physical activity, and stress with the
incidence of premenstrual syndr ome in female students of the Faculty of Medicine
at the University of North Sumatra. Methods . This study is an analytical
observational study with a cross sectional approach. The research sample,
consisting of 143 individuals, was selected using consecutive sampling. Data were
collected through The Shortened Premenstrual Assessment Form (SPAF)
questionnaire for assessing premenstrual syndrome, t he Pittsburgh Sleep Quality
Index (PSQI) for measuring sleep quality, the Global Physical Activity
Questionnaire (GPAQ) for assessing physical activity, and the Perceived Stress
Scale (PSS) for measuring stress. Chi square tests were conducted to assess the
relationship between BMI, sleep quality, physical activity, and stress with PMS.
Results . The Chi square analysis yielded p values of 0.08 (p < 0.05) for BMI, 0.15
(p 0.05) for sleep quality, 0.599 (p > 0.05) for physical activity, and 0.001 (p <
0.05) for stress. Conclusion . There is a significant positive relationship between
BMI and stress with the incidence o f PMS in female students of the Faculty of
Medicine at the University of North Sumatra. No significant evidence of a
relationship was found between sleep quality and physical activity with the
incidence of PMS in these students.93 PagesSkripsi Sarjan
Gambaran Tingkat Pengetahuan Mahasiswi Baru FK USU Angkatan 2020 Mengenai Dismenorea dan Tindakan untuk Mengatasinya
No full textBackground. Dysmenorrhoea is pain before or during menstruation, with symptoms of uterine pain
or cramps in the abdomen with different variations for each woman. Dysmenorrhoea is one of the
most common gynecologic problems in adolescent girls which can impair both activity and
psychological state. Objectives. This study aims to describe the level of knowledge of new students
of the FK USU 2020 regarding dysmenorrhoea and actions to overcome it. Methods. This research
design is descriptive qualitative with a cross-sectional design. Respondents of this study were 159
respondents from 159 participants, who were new students of the Faculty of Medicine USU 2020
who had a history of menstrual pain. The sampling technique used was Total Sampling. Respondents
fill out a questionnaire via google-form which is sent to each respondent and then will sign the
informed consent, and answer according to the questions in the questionnaire. The data is then
processed using statistical data processing programs. Result. From the results of the study, was
found that the incidence of dysmenorrhoea in new students of Faculty of Medicine USU 2020 was
156 people (98.1%) of the total respondents, found the level of knowledge of respondents on the
problem of menstrual pain was quite good, 76 people (47.8%), then a low level of knowledge was
28 people (17.6%). The handling effort made by the majority of the 2020 USU FK new students was
rest, 157 people (15.92%). Conclusion. The incidence of dysmenorrhoea in new students of the
Faculty of Medicine USU 2020 is high, therefore a good knowledge of menstrual pain will provide
an effective strategist for managing menstrual pain, both pharmacology and non-pharmacological.Latar Belakang. Dismenorea merupakan nyeri sebelum atau selama menstruasi, dengan gejala
nyeri uterus atau kram di bagian perut dengan variasi yang berbeda-beda pada setiap wanita.
Dismenorea juga merupakan salah satu masalah ginekologi yang paling umum terjadi pada remaja
putri yang dapat mengganggu aktivitas dan psikologis Tujuan. Penelitian ini bertujuan untuk
mengetahui gambaran tingkat pengetahuan mahasiswi baru FK USU angkatan 2020 mengenai
dismenorea dan tindakan untuk mengatasinya Metode. Desain penelitian ini adalah kualitatif
deskriptif dengan desain Cross-Sectional. Responden penelitian ini adalah 159 responden dari 159
orang, yang merupakan mahasiswi baru FK USU angkatan 2020 yang memiliki riwayat nyeri haid.
Teknik Pengambilan sampel yang digunakan adalah Total Sampling. Responden mengisi kuesioner
melalui google-form yang dikirimkan ke masing-masing responden, dan selanjutnya akan
menandatangani informed consent, dan menjawab sesuai dengan pertanyaan yang ada di kuesioner.
Data kemudian diolah dengan menggunakan program pengolahan data statistik. Hasil. Dari hasil
penelitian, didapatkan insidensi terjadinya dismenorea pada mahasiswi baru FK USU Angkatan
2020 adalah 156 orang (98,1%) dari jumlah seluruh responden, didapati tingkat pengetahuan
responden terhadap masalah nyeri haid cukup baik yaitu tingkat pengetahuan baik sebanyak 76
orang (47,8%), kemudian tingkat pengetahuan kurang sebanyak 28 orang (17,6%). Usaha
penanganan yang dilakukan mayoritas pada mahasiswi baru FK USU angkatan 2020 adalah
istirahat yaitu 157 orang (15,92%). Kesimpulan. Insidensi terjadinya dismenorea pada mahasiswi
baru FK USU angkatan 2020 cukup tinggi, oleh karena itu, pengetahuan yang baik tentang nyeri
haid akan memberikan hasil usaha penanganan nyeri haid yang sesuai, baik secara farmako dan
non-farmako.112 HalamanSkripsi Sarjan
Perbandingan Kadar Matriks Metalloproteinase-2 (MMP-2) Serum pada Wanita dengan Ovarium Normal dan Wanita dengan Kista Ovarium Jinak
No full textBackground: Benign ovarian cysts are common gynecological problem that
found in women including benign cyst to neoplastic mass. There is still no
screening tool and sensitive markers for ovarian tumors in small size is an
obstacle for early detection of ovarian tumors. The Metalloproteinase-2 (MMP-2)
matrix is a protein that controls cell degradation, one of which is in the follicular
wall which may play a role in the development of ovarian tumors.
Objective: To analyze the comparison of serum MMP-2 levels in women with
normal ovaries and women with benign ovarian cysts.
Method: This study was an observational analytic study that analyzed with a
cross sectional design, conducted at H. Adam Malik General Hospital Medan and
Network Hospital of the Faculty of Medicine, Universitas Sumatera Utara, Medan
with 26 samples from September 2019 to October 2019 and fulfilling the
inclusion and exclusion criteria .
Result: In studies involving 26 research samples. The mean value of serum
MMP-2 levels was found to be higher in women with normal ovaries (362.31 ±
38.17 ng / ml) compared to women with benign ovarian cysts (261.69 ± 41.17 ng
/ ml ). To assess mean serum MMP-2 levels differences in women with normal
ovaries and women with benign ovarian cysts, a Mann Whitney test was
performed and a p value <0.001 was obtained which indicates a significant
difference in mean MMP-2 serum levels between the two groups.
Conclusion: Women with benign ovarian cysts have significantly lower MMP-2
levels compared to women who have normal ovaries.Latar Belakang: Kista ovarium jinak merupakan masalah ginekologis yang umum
ditemukan pada wanita baik kista yang bersifat fisiologis dan neoplastik. Belum terdapat
alat skrining dan marker sensitif pada tumor ovarium pada ukuran kecil merupakan
kendala untuk deteksi dini tumor ovarium. Matriks Metalloproteinase-2 (MMP-2)
merupakan protein pengontrol degradasi sel, salah satunya pada dinding folikel yang
mungkin berperan dalam perkembangan tumor ovarium.
Tujuan: Untuk mengetahui perbandingan kadar MMP-2 serum pada wanita dengan
ovarium normal dan wanita dengan kista ovarium jinak.
Metode: Penelitian ini merupakan penelitian analitik observasional yang dianalisis
dengan rancangan cross sectional yang di lakukan di RSUP H. Adam Malik Medan dan
RS Jejaring Fakultas Kedokteran Universitas Sumatera Utara Medan dengan jumlah
sampel 26 sampel dari bulan September 2019 sampai bulan Oktober 2019 dan memenuhi
kriteria inklusi dan eksklusi.
Hasil: Pada penelitian yang melibatkan sebanyak 26 sampel penelitian. Untuk nilai
Rerata kadar serum MMP-2 ditemukan lebih tinggi pada sampel wanita dengan ovarium
normal dengan kadar (362,31 ± 38,17 ng/ml) dibandingkan wanita dengan kista ovarium
jinak dengan kadar (261,69 ± 41,17 ng/ml). Untuk menilai perbedaan rerata kadar serum
MMP-2 pada wanita dengan ovarium normal dan wanita dengan kista ovarium jinak,
dilakukan uji Mann Whitney dan diperoleh hasil p value <0,001 yang menandakan
adanya perbedaan yang signifikan rerata kadar serum MMP-2 antara kedua kelompok
tersebut.
Kesimpulan: Wanita dengan kista ovarium jinak memiliki kadar MMP-2 yang lebih
rendah secara signifikan dibandingkan dengan wanita yang memiliki ovarium yang
normal.96 HalamanTesis Magiste
Pengaruh Peran Tenaga Kesehatan terhadap Kesipan Wanita dalam Menghadapi Keluhan Menopause di Rumah Sakit Umum Daerah dr Zainoel Abidin Banda Aceh Provinsi Aceh
No full textThe knowledge of menopause woman is still poor. The result of preliminary
study conducted in dr. Zainoel Abidin District General Hospital, Banda Aceh,
involving 30 women who were having menopause showed that they did not have any
knowledge about menopause. Health officer can improve the knowledge of that
woman.
The purpose of this cross-sectional study conducted in dr. Zainoel Abidin
District General Hospital, Banda Aceh was to analyze the influence of the roles of
health workers (motivator, facilitator, and counselor) on the preparedness of women
in facing their complaint of menopause in dr. Zainoel Abidin District General
Hospital, Banda Aceh. The sample for this study were all the 67 women having
menopause who have visited the geriatric polyclinic of dr. Zainoel Abidin District
General Hospital, Banda Aceh, at least two times. These samples were selected
through proportional sampling technique. The data obtained were analyzed through
multiple logistic regression tests at level of confidence 95% (a-< 0.05).
The result of this study showed that motivator (p = 0.022), facilitator (p =
0,486), and counselor (p=0,976) had influence on the preparedness of women in
facing their complaint of menopause. The most dominant variable that had influence
on the preparedness of women in facing their complaint of menopause was the role of
health workers as motivator (p=0,022).
The management of dr. Zainoel Abidin District General Hospital, Banda
Aceh is suggested to improve the training on menopause for their staff and to
increase interpersonal communication for the women who are having menopause.Untuk meningkatkan kesiapan wanita dalam menghadapi keluhan menopause
dibutuhkan peran tenaga kesehatan (motivator, fasilitator dan konselor) yang baik.
Hasil studi pendahuluan di Rumah sakit Umum Daerah dr. Zainoel Abidin Banda
Aceh pada 30 orang wanita menopause didapatkan mereka tidak mempunyai
pengetahuan tentang menopause. Di poli geriatri tenaga kesehatan melakukan
pengobatan dan konseling, tetapi karena banyaknya pasien dan kurangnya waktu (hari
Jum’at poli tutup jam 12.00 WIB), menyebabkan tenaga kesehatan tidak dapat
berperan secara optimal, dengan kata lain peran motivator, fasilitator dan konselor
sering tidak dapat dijalankan secara bersamaan.
Penelitian ini bertujuan untuk menganalisis pengaruh peran tenaga kesehatan
(motivator, fasilitator dan konselor) terhadap kesiapan wanita dalam menghadapi
keluhan menopause di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh.
Jenis penelitian adalah penelitian cross-sectional. Penelitian ini dilakukan di Rumah
Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh . Sampel dalam penelitian ini
adalah seluruh wanita menopause yang telah melakukan kunjungan minimal dua kali
di poli geriatri Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh. Jumlah
sampel 67 orang wanita menopause, dengan tehnik pengambilan sampel proportional
sampling. Analisa data menggunakan uji regresi logistik berganda pada taraf
kepercayaan 95% (α<0,05).
Hasil penelitian menunjukkan terdapat pengaruh motivator (p = 0,022) ,
fasilitator (p=0,486) dan konselor (p=0,976) terhadap kesiapan wanita dalam
menghadapi keluhan menopause. Variabel yang paling dominan yang berpengaruh
terhadap kesiapan wanita dalam menghadapi keluhan menopause adalah peran tenaga
sebagai motivator (p=0,022).
Disarankan agar pihak manajemen Rumah Sakit Umum Daerah dr. Zainoel
Abidin Banda Aceh meningkatkan pelatihan menopause bagi stafnya serta
meningkatkan komunikasi interpersonal bagi wanita menopause.94 HalamanTesis Magiste
Knowledge Level Of Students of the Faculty of Medicine, University Of North Sumatera Class 2021 on Ovarian Tumors
No full textOvarian tumors are a form of reproductive disease that often attacks women. Ovarian
tumors consist of malignant and benign tumors. Not maintaining cleanliness is one of the causes of
ovarian tumors. And we can also get ovarian tumors from family/genetics. Objective: to analyze
the level of knowledge of students at the Faculty of Medicine, University of North Sumatra class
of 2021 regarding ovarian tumors. Method: by Unvariate analysis test, which takes existing data
and a real picture. Conclusion: overall, the level of knowledge of USU FK students about ovarian
tumors is good.62 PagesSkripsi Sarjan
Korelasi Kadar Β-Hcg Serum terhadap Kadar Tsh, T3, dan T4 pada Molahidatidosa di Rsup.H.Adam Malik dan Rsud Dr. Pingadi Medan Periode Tahun 2008 - 2012
No full textBackroud : Clinically, proved of hyperthyroid detected in 7% of complete
hydatidiform mole patients, but more often laboratorically. Thyroid
hyperfunction in mole pregnancy related to excessive of hCG level that
has thyroid stimulant activity. High level of hCG can stimulate thyroid gland
with supress TSH released from pituitary and then can effect T3 and T4
hormone secretion.
Aim :To analyze correlation of β-hCG serum level to TSH, T3, and T4
levelin hydatidiform mole at Adam Malik anddr. Pingadi Medan hospital
between 2008 - 2012
Method :This analitic correlative study was used retrospective approach
with secunder data from medical record of Adam Malik and dr. Pirngadi
Medan hospital.
Results : Frommedical record data, there was 45 hydatidiform mole cases
that fulfill inclusion criteria. Patients characteristic based on age that the
majority was 31-35 years old (20%), there was 28 of cases (62.2%) with
parity < 3, the most often chief complain was vaginal bleeeding in 84.4%
cases, majority of hydatidiform mole cases was diagnosed at > 10 weeks
gestational age in 38 of cases, fundal height bigger than gestational age in
29 of cases (64.4%), and the mean of sistole and diastole blood
presseure was 130.22 ± 20.50 mmHg and 80.22 ± 11.58 mmHg,
respectively. Mean of β-hCG, TSH, T3 and T4 level was 344561.07 ±
327135.07mIU/mL, 0.38 ± 0.60µIU/mL, 2.06 ± 1.53ng/dL, 13.76 ± 6.40
µg/mL respectively. Correlation between β-hCG and TSH was with r =
-0.321 (p=0.031), β-hCG and T3 with r=0.574 (p=0.0001), and β-hCG and
T4 with r=0.606 (p=0.0001).
Conclusion : There was negative correlation between β-hCG and TSH
significantlywith weak correlation and positive coorelation between β-hCG
and T3, β-hCG and T4significantly with intermediete correlation,
respectively.Latar Belakang :Secara klinis bukti dari hipertiroidisme terdeteksi pada
7% pasien Molahidatidosa Komplit, tetapi, secara laboratorium lebih sering
terjadi.Hiperfungsi tiroid pada kehamilan molahidatidosa dikaitkan dengan
berlebihnya hCG, yang mempunyai aktivitas pemicu tiorid. Tingginya
kadar hCG akan merangsang kelenjar tiroid dengan menekan pelepasan
TSH dari kelenjar hipofisis sehingga akan mempengaruhi juga sekresi
hormon T3 dan T4.
Tujuan :Menganalisa korelasi kadar β-hCG serum terhadap kadar TSH,
T3 dan T4 pada molahidatidosa di RSUP. H. Adam Malik dan RSUD dr.
Pirngadi Medan periode tahun 2008 – 2012.
Metode : Penelitian ini bersifat analitik korelatif dengan studi retrospektif
dan menggunakan data sekunder dari catatan rekam medis RSUP.H.
Adam Malik dan RSUD. dr. Pirngadi Medan.
Hasil : Dari data rekam medis didapatkan 45 kasus molahidatidosa yang
memenuhi kriteria inklusi. Karakteristik pasien berdasarkan usia yang
terbanyak adalah usia 31-35 tahun (20%), paritas < 3 sebanyak 28 kasus
(62.2%), mayoritas keluhan yang paling sering adalah perdarahan
pervaginam sebanyak 84.4%, usia kehamilan saat di diagnosa yang paling
banyak pada usia kehamilan > 10 minggu pada 38 kasus, tinggi fundus
uteri yang lebih besar dari usia kehamilan terdapat pada 29 kasus
(64.4%), dan nilai rerata tekanan darah sistole dan diastole adalah 130.22
± 20.50 mmHg dan 80.22 ± 11.58 mmHg. Nilai rerata β-hCG, TSH, T3 dan
T4 masing-masing adalah 344561.07 ± 327135.07mIU/mL, 0.38 ±
0.60µIU/mL, 2.06 ± 1.53ng/dL, 13.76 ± 6.40 µg/mL. Korelasi antara β-hCG
dengan TSH adalah dengan nilai r = -0.321 (p=0.031), β-hCG dengan T3
dengan nilai r=0.574 (p=0.0001), dan β-hCG dengan T4 dengan nilai
r=0.606 (p=0.0001).
Kesimpulan : Terdapat korelasi negatif yang bermakna antara β-hCG
dengan TSH dengan kekuatan korelasi yang lemah serta korelasi positif
yang bermakna antara β-hCG dengan T3 dan antara β-hCG dengan
T4dengan kekuatan korelasi sedang.68 Halama
Hubungan Hiponatremia dengan Skor Child-Pugh pada Penderita Sirosis Hati di RSUP Haji Adam Malik Tahun 2015
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Sirosis hepatis merupakan salah satu penyebab utama kematian dan menyebabkan komplikasi fatal seperti asites , encephalopati hepatik dan perdarahan varises esophagus. Pasien sirosis hepatis sering mengalami gangguan fungsi ginjal dan elektrolit dan hiponatremia merupakan keadaan yang paling sering dijumpai. Penelitan ini bertujuan untuk melihat hubungan kadar natrium dengan tingkat keparahan sirosis hepatis yang diukur dengan skor Child-Pugh.
Metode
Penelitian ini merupakan pelelitian cross –sectional yang dilukukan di RS H. Adam Malik Medan dari Januari sampai Desember 2015. Hubungan antara kadar hiponatremia dengan skor Child-Pugh dilakukan dengan uji T test independent dan Chi-Square.
Hasil
Dari 39 pasien sirosis hepatis, dijumpai 13 pasien (33,3%) kadar natrium dibawah 130 mmol/L. Dari 13 pasien tersebut, dua pasien memiliki skor Child-Pugh B dan 11 orang memiliki skor Child-Pugh C. Kadar rata-rata natrium pada pasien dengan skor Child-Pugh B lebih tinggi dibandingkan dengan pasien sirosis hati dengan skor Child-Pugh C (133,75 ± 3,87 banding 130,00 ± 5,00). Terdapat hubungan yang signifikan antara hiponatremia dengan skor Child-Pugh, dimana hiponatremia lebih banyak dijumpai pada penderita sirosis hati dengan skor Child-Pugh C dibandingkan skor Child-Pugh B (28,2% banding 5,1%, P < 0,021).
Kesimpulan
Terdapat hubungan yang signifikan antara hiponatremia dengan derajat keparahan sirosis hati yang diukur dengan skor Child-Pugh.Introduce
Liver cirrhosis is one of the leading causes of death and causes fatal complications such as ascites, hepatic encephalopathy and variceal esophagus Hemorrhage. Liver cirrhosis patients often have impaired kidney function and electrolytes and hyponatremia is a condition most often encountered. This research aims to examine the relationship sodium levels with severity of liver cirrhosis as measured by the Child-Pugh score.
Methodology
This study is a cross-sectional which is conducted at Adam Malik Hospital from January to December 2015. The relationship between the levels of hyponatremia with Child-Pugh score performed by independent T test and Chi-Square.
Result
Of the 39 patients with liver cirrhosis, 13 patients (33.3%) have sodium levels less than 130 mmol / L. Of the 13 patients, two patients had Child-Pugh score B and 11 had Child-Pugh score C. The mean of sodium levels in patients with Child-Pugh score B is higher than patients with liver cirrhosis with Child-Pugh score C (133.75 ± 3.87 130.00 ± 5.00 appeal). There is a significant relationship between hyponatremia with Child-Pugh score, where hyponatremia more common in patients with liver cirrhosis with Child-Pugh score C than the score Child-Pugh B (28.2% vs 5.1%, P <0.021).
Conclusion
There is a significant correlation between the severity of hyponatremia with cirrhosis of the liver as measured by the Child-Pugh score.44 HalamanSkripsi Sarjan
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