1,214 research outputs found

    Advertisement for Langer\u27s book on the Nonpartisan League, 1920

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    In 1920, Attorney General Langer wrote The Nonpartisan League: its birth, activities and leaders. The book reveals [the] trail of graft which led to the forming of the League by A.C. Townley in 1915. This advertsement is dated October 8, 1920 and refers to the author as General Langer.https://commons.und.edu/langer-papers/1004/thumbnail.jp

    Memorandum from Unknown Author to Senator Langer Regarding Clearance for Reimbursement of Expenses, February 21, 1955

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    This memorandum dated February 21, 1955, from unknown author to United States (US) Senator William Langer, written on US Senate memorandum stationery, reads: Senator: Mr. Chumbers [sic] called, said he has talked to Commissioner Emmons, but Mr. Emmons has been unable to clear with the Secretary of the Interior as to the Federal government\u27s reimbursing the State of N. Dak. for their expenses. Because of the Holiday tomorrow, he may not get a report from the Secretary before Thursday. Mr. Chumbers most likely refers to Pete Chumbris, to whom other documents in the Langer papers of this period refer. Commission Emmons most likely refers to Glenn L. Emmons, Commissioner of the United States (US) Bureau of Indian Affairs. See also: Letter from Ben Youngbird and Carl Whitman, Jr. Requesting Meeting, February 1955https://commons.und.edu/langer-papers/1861/thumbnail.jp

    Memo to Senator Langer Indicating that Marin Cross Requests Langer\u27s Presence at Meeting with the US Interior and Insular Affairs Subcommittee, May 10, 1948

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    This memo dated May 10, likely from 1948, does not have an author and is addressed to United States (US) Senator William Langer. The memo informs Langer that Three Affiliated Tribes member Martin Cross was in that morning and would like Langer to attend a meeting with the US Interior and Insular Affairs Subcommittee later that day. There are some shorthand notes on the memo.https://commons.und.edu/langer-papers/1382/thumbnail.jp

    Autonomic and circulatory alterations persist despite adequate resuscitation in a 5-day sepsis swine experiment.

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    Autonomic and vascular failures are common phenotypes of sepsis, typically characterized by tachycardia despite corrected hypotension/hypovolemia, vasopressor resistance, increased arterial stiffness and decreased peripheral vascular resistance. In a 5-day swine experiment of polymicrobial sepsis we aimed at characterizing arterial properties and autonomic mechanisms responsible for cardiovascular homeostasis regulation, with the final goal to verify whether the resuscitation therapy in agreement with standard guidelines was successful in restoring a physiological condition of hemodynamic profile, cardiovascular interactions and autonomic control. Twenty pigs were randomized to polymicrobial sepsis and protocol-based resuscitation or to prolonged mechanical ventilation and sedation without sepsis. The animals were studied at baseline, after sepsis development, and every 24 h during the 3-days resuscitation period. Beat-to-beat carotid blood pressure (BP), carotid blood flow, and central venous pressure were continuously recorded. The two-element Windkessel model was adopted to study carotid arterial compliance, systemic vascular resistance and characteristic time constant τ. Effective arterial elastance was calculated as a simple estimate of total arterial load. Cardiac baroreflex sensitivity (BRS) and low frequency (LF) spectral power of diastolic BP were computed to assess autonomic activity. Sepsis induced significant vascular and autonomic alterations, manifested as increased arterial stiffness, decreased vascular resistance and τ constant, reduced BRS and LF power, higher arterial afterload and elevated heart rate in septic pigs compared to sham animals. This compromised condition was persistent until the end of the experiment, despite achievement of recommended resuscitation goals by administered vasopressors and fluids. Vascular and autonomic alterations persist 3 days after goal-directed resuscitation in a clinically relevant sepsis model. We hypothesize that the addition of these variables to standard clinical markers may better profile patients' response to treatment and this could drive a more tailored therapy which could have a potential impact on long-term outcomes

    A Notecard of Notes Filed in William Langer\u27s Papers, Likely 1950s

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    This note card, filed with United States (US) Senator William Langer\u27s papers along with other documents from the 1950s, contains several handwritten notes and some shorthand writing.https://commons.und.edu/langer-papers/1896/thumbnail.jp

    Abstrakt - Affektiv - Multimodal: zur Verarbeitung von Bewegtbildern im Anschluss an Cassirer, Langer und Krois

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    Lässt sich die Behauptung stützen, dass zwischen Gestaltungsweisen und Wahrnehmungsweisen eine Analogie besteht? Aufbauend auf den kulturanthropologischen Forschungen von Ernst Cassirer, Susanne K. Langer und John M. Krois sowie der Analyse eines Tapes der Schweizer Videokünstlerin Pipilotti Rist gilt es diese ursprünglich von der Formalen Ästhetik aufgeworfene These zu untermauern

    Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy.

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    Neoadjuvant therapy has been successfully introduced in the treatment of locally advanced gastrointestinal malignancies, particularly esophageal, gastric, and rectal cancers. The effects of preoperative chemo- or radiochemotherapy can be determined by histopathological investigation of the resection specimen following this treatment. Frequent histological findings after neoadjuvant therapy include various amounts of residual tumor, inflammation, resorptive changes with infiltrates of foamy histiocytes, foreign body reactions, and scarry fibrosis. Several tumor regression grading (TRG) systems, which aim to categorize the amount of regressive changes after cytotoxic treatment in primary tumor sites, have been proposed for gastroesophageal and rectal carcinomas. These systems primarily refer to the amount of therapy-induced fibrosis in relation to the residual tumor (e.g., the Mandard, Dworak, or AJCC systems) or the estimated percentage of residual tumor in relation to the previous tumor site (e.g., the Becker, Rödel, or Rectal Cancer Regression Grading systems). TRGs provide valuable prognostic information, as in most cases, complete or subtotal tumor regression after neoadjuvant treatment is associated with better patient outcomes. This review describes the typical histopathological findings after neoadjuvant treatment, discusses the most commonly used TRG systems for gastroesophageal and rectal carcinomas, addresses the limitations and critical issues of tumor regression grading in these tumors, and describes the clinical impact of TRG

    Laos: Search For Peace in the Midst of War

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    Report on peacekeeping efforts in Laos on the part of the neutralist wing of the Royal Government and the political and military conflict between communists and others in the country.Pre-publication version of the article (for the Rand Corp) in the the Asian Survey. Search for Peace in the Midst of War ;Paul F. Langer; Asian Survey, Vol. 8, No. 1, A Survey of Asia in 1967- Part I (Jan., 1968), pp. 80-8
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