309,960 research outputs found
Castaneda, M. Ruiz -- 1953-65 -- Correspondence, Individual -- letter, 1965-02-02
No full textLetter from Ruiz-Castaneda, M. to Sabin, Albert B. dated 1965-02-02.Sabin Collection Fair Use Policy</a
Contribuciones a la Lingüística y a la Comunicación Social. Tributo a Vitelio Ruiz Hernández
No full textEn el volumen se reúnen distintos trabajos relacionados con la Adquisición del español como lengua primera (L1), el Análisis del discurso, la Antropología lingüística, el Español como lengua extranjera (ELE), el Español como segunda lengua (EL2), la Fonética, la Fonología, las Humanidades digitales, la Lexicografía, la Lexicología, la Lingüística computacional, la Lingüística de corpus, etc
In vivo effects of romidepsin on T-cell activation, apoptosis and function in the BCN02 HIV-1 kick&kill clinical trial
No full textCopyright © 2020 Rosás-Umbert, Ruiz-Riol, Fernández, Marszalek, Coll, Manzardo,Cedeño, Miró, Clotet, Hanke, Moltó, Mothe, Brander and the BCN02 study group.This is an open-access article distributed under the terms of the Creative CommonsAttribution License (CC BY). The use, distribution or reproduction in other forumsis permitted, provided the original author(s) and the copyright owner(s) are creditedand that the original publication in this journal is cited, in accordance with acceptedacademic practice. No use, distribution or reproduction ispermitted which does notcomply with these terms.Romidepsin (RMD) is a well-characterized histone deacetylase inhibitor approved for the treatment of cutaneous T-cell lymphoma. in vitro and in vivo studies have demonstrated that it is able to induce HIV-1 gene expression in latently infected CD4+ T cells from HIV-1+ individuals on suppressive antiretroviral therapy. However, in vitro experiments suggested that RMD could also impair T-cell functionality, particularly of activated T cells. Thus, the usefulness of RMD in HIV-1 kick&kill strategies, that aim to enhance the immune system elimination of infected cells after inducing HIV-1 viral reactivation, may be limited. In order to address whether the in vitro observations are replicated in vivo, we determined the effects of RMD on the total and HIV-1-specific T-cell populations in longitudinal samples from the BCN02 kick&kill clinical trial (NCT02616874). BCN02 was a proof-of-concept study in 15 early treated HIV-1+ individuals that combined MVA.HIVconsv vaccination with three weekly infusions of RMD given as a latency reversing agent. Our results show that RMD induced a transient increase in the frequency of apoptotic T cells and an enhanced activation of vaccine-induced T cells. Although RMD reduced the number of vaccine-elicited T cells secreting multiple cytokines, viral suppressive capacity of CD8+ T cells was preserved over the RMD treatment. These observations have important implications for the design of effective kick&kill strategies for the HIV-1 cure.Peer ReviewedArticle signat per 13 autors/es i un grup de recerca: Miriam Rosás-Umbert,Marta Ruiz-Riol, Marco A. Fernández, Marta Marszalek, Pep Coll, Christian Manzardo, Samandhy Cedeño, José M. Miró, Bonaventura Clotet, Tomáš Hanke, José Moltó, Beatriz Mothe, Christian Brander, and the BCN02 study groupPostprint (published version
Ruiz, M.
No full textCentro Asturiano membership record of M. Ruiz; Socio Number: 82487.https://digitalcommons.usf.edu/asturiano_membership/5311/thumbnail.jp
[Telegram from Daniel Ruiz to Frank M. Pinedo]
No full textCarbon copy of a telegram sent to Frank M. Pinedo from Daniel Ruiz, informing Pinedo that John J. Herrera will be attending the Open House in Bryan, Texas. The date on this document is May 13th, but no year is specified
Recommended from our members
Oral History Interview with Ramon M. Ruiz, September 29, 2012
No full textInterview with Ramon Ruiz, a civil servant of the Department of Education and advocate for Hispanic education from La Copita, Texas. Ruiz discusses his family history, growing up, school in Kingsville, local relations between Mexicans and white people, high school football, playing for North Texas State, becoming a coach for elementary school, joining the Job Corps, teaching inmates, working with school districts on desegregation in Texas, and work on various federal education programs in Washington with an emphasis on Hispanic communities and cooperation with Mexico. In appendix is a biography of Ruiz and his resumé
RUIZ, M.
No full textLetter from Mr. M. Ruiz to Gen. Francisco R. Serrano informing that some offices of the Obregonista party were open in the city of Puebla, where some guns have been arriving and he fears that an attack against him can happen when he visits Puebla. / Carta del Sr. M. Ruiz al Gral. Francisco R. Serrano informando que en la ciudad de Puebla se instalaron unas oficinas del Partido Obregonista a donde se han estado llevando armas y teme se cometa un atentado en su contra cuando visite Puebla
RUIZ, M.
No full textLetter from Mr. M. Ruiz to Gen. Francisco R. Serrano informing that some offices of the Obregonista party were open in the city of Puebla, where some guns have been arriving and he fears that an attack against him can happen when he visits Puebla. / Carta del Sr. M. Ruiz al Gral. Francisco R. Serrano informando que en la ciudad de Puebla se instalaron unas oficinas del Partido Obregonista a donde se han estado llevando armas y teme se cometa un atentado en su contra cuando visite Puebla
Factura, 1925 en. 1, Madrid, de Antonio Ruiz Elías a Sr. Don Santiago M. Palacio
No full textFactura impresa mecanografiada en tinta azulAlcance y contenido: Versa sobre los honorarios de cuatro asistencias médicas al Sr. Santiago M. PalacioEn el membrete: "El Doctor Antonio Ruiz Elías / E. L. M. / s/c San Mateo, 30, 2º izqda. / Teléfono 20-49 M. / Consulta de 3 a 4"Recibí firmado y rubricado por A. Ruiz ElíasMembrete con los datos del nombre, actividad y dirección del establecimiento en la parte superior en diferentes líneas. En el lateral izquierdo de la página del interior, datos de la gráfica: "Sucesor de R. Velasco"Papel en color crema con rayas, con forma de cuadernill
Tartamura agatelin Bustamante & Ruiz 2017
No full textTartamura agatelin Bustamante & Ruiz, 2017 Tartamura agatelin Bustamante & Ruiz, 2017: 326, figs 2, 8F, 18–19 (Holotype Ƌ: ECUADOR: Orellana: Yasuní Reserve Station Area, 0.6806°S, 76.3940°W, 260 m a.s.l., leg. W.P. Maddison, 9.VIII.2011 (roadside tree), QCAZ—re-examined). Description and diagnosis. See Bustamante & Ruiz (2017). Other material examined (new records). ECUADOR: Orellana: Yasuní Reserve Station Area, 0.6806°S, 76.3940°W, 260 m a.s.l., leg. W.P. Maddison, 9.VIII.2011 (roadside tree), 1Ƌ (UBC-SEM); Lagunas trail, 0.6722°S, 76.3994°W, leg. W.P. Maddison, E. Piasick & M. Vega, 280 m a.s.l., 5.VIII.2011 (day-old treefall), 1Ƌ (UBC-SEM). Distribution. Known only from a few localities in Orellana, Ecuador.Published as part of Bustamante, Abel A. & Ruiz, Gustavo R. S., 2020, New species and records of thiodinines from North and South America (Araneae Salticidae: Salticinae: Thiodinini), pp. 115-140 in Zootaxa 4899 (1) on page 123, DOI: 10.11646/zootaxa.4899.1.6, http://zenodo.org/record/440075
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