67 research outputs found
Raising a Child With Congenital Muscular Dystrophy: Impact on the Family
No full textAbstract
Date Presented 3/31/2017
This study examines the impact on families of raising children with congenital muscular dystrophy. The findings expand the understanding of challenges they face and contribute to an evidence-based approach for families.
Primary Author and Speaker: Yoonjeong Lim
Additional Authors and Speakers: Consuelo Kreider, Roxanna Bendixen</jats:p
Examining the Effects of the Mealtime PREP Intervention for Toddlers With Sensory Food Aversions
No full textAbstract
Date Presented 3/30/2017
The Mealtime PREP intervention shows promise to improve dietary variety and mealtime behaviors and lower risk of nutritional deficiency in toddlers with sensory food aversions. Moderate to large effect sizes were observed in a small sample of 11 families trained to deliver this intervention in the home.
Primary Author and Speaker: Angela Caldwell
Contributing Authors: Roxanna Bendixen, Cynthia Danford, Lauren Terhorst, Elizabeth Skidmore</jats:p
Remittance behavior among new U.S. immigrants
No full textI analyze remittance behavior among new legal immigrants in the US using a nationally representative survey of immigrants admitted to legal permanent residency in 2003. I find that the distribution of remittances is skewed to the right, with a small number of immigrants sending very large amounts. I find evidence against the pure altruism model and find that remittances may be used for investments in the home country. Using longitudinal data from the NIS, I construct a measure of permanent income and estimate remittance-income elasticities. I find that large country differentials in remittance behavior are only partially explained by observable characteristics of the donor, recipient and origin country. Future work will incorporate later waves of the 2003 NIS in order to observe return migration (and its relationship to remittance and home country investment decisions) and life cycle income-remittance movements.Immigrants ; Remittances
A mixed‐methods investigation of sensory response patterns in Barth syndrome: A clinical phenotype?
No full textReview of Occupational Therapy Research in the Practice Area of Children and Youth
No full textAbstract
We conducted a systematic review focusing on articles in the occupational therapy practice category of Children and Youth published in the American Journal of Occupational Therapy over the 2-yr period of 2009–2010. We used the frameworks of the International Classification of Functioning, Disability and Health (ICF) and Positive Youth Development (PYD) to explore occupational therapy research progress toward the goals of the Centennial Vision. We organized 46 research articles by research type and classified them within these two frameworks. Most reviewed published research investigated variables representing constructs falling within the ICF domains of Body Functioning and Activity. The effect of occupational therapy interventions on PYD resided primarily in building competence. To meet the tenets of the Centennial Vision, occupational therapists must document changes in children’s engagement in everyday life situations and build the evidence of occupational therapist’s efficacy in facilitating participation.</jats:p
Participation and quality of life in children with Duchenne muscular dystrophy using the International Classification of Functioning, Disability, and Health
No full textAbstract Background Duchenne muscular dystrophy (DMD) is characterized by muscle damage and progressive loss of muscle function in male children. DMD is one of the most devastating genetically linked neuromuscular diseases for which there is currently no cure. Most clinical studies for DMD utilize a standard protocol for measurement exploring pathophysiology, muscle strength and timed tasks. However, we propose that examining broader components of health as emphasized by the International Classification of Functioning, Disability and Health-Children and Youth Version (ICF-CY) may be of great value to children and their families, and important outcomes for future clinical trials. Methods Fifty boys with DMD and 25 unaffected age-matched boys completed two self-report measures: the Children’s Assessment of Participation and Enjoyment and the Pediatric Quality of Life InventoryTM 4.0. We investigated differences between the two groups with regard to participation in life activities and perceived quality of life (QoL). Additionally, we compared participation in activities and QoL in both cohorts of younger and older boys. Results Participation in physical activities was significantly lower in boys with DMD than unaffected boys. Perceived QoL was markedly diminished in children with DMD relative to unaffected controls, except in the emotional domain. The amount of time boys engage in an activity, as well as participation in social activities, declined for our older boys with DMD but no changes were observed for our older unaffected boys. For both groups, QoL remained constant over time. Conclusions The ICF-CY provides a conceptual framework and specific terminology that facilitates investigation of the consequences of impairment in children and youth. Our study is one of the first to explore participation in a cohort of boys with DMD. It was not surprising that activities of choice for boys with DMD were less physical in nature than unaffected boys their age, but the consequences of less social engagement as the boys with DMD age is of great concern. Results from our study underscore the need to further evaluate activities that children elect to participate in, with special emphasis on facilitators and barriers to participation and how participation changes throughout the course of a disease.</p
The Relationship of Home Range to Functional Status and Cognitive Status of Frail Elders
No full textA Pilot Study Examining Activity Participation, Sensory Responsiveness, and Competence in Children with High Functioning Autism Spectrum Disorder
No full textGenome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
No full textGenetic factors have been implicated in stroke risk, but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke and its subtypes in 3,548 affected individuals and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 affected individuals and 6,281 controls. We replicated previous associations for cardioembolic stroke near PITX2 and ZFHX3 and for large vessel stroke at a 9p21 locus. We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10<sup>−11</sup>; odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28–1.57). All four loci exhibited evidence for heterogeneity of effect across the stroke subtypes, with some and possibly all affecting risk for only one subtype. This suggests distinct genetic architectures for different stroke subtypes
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