135 research outputs found

    Memories of a Newfoundland Seaman by Wilfred G. Rowe (1916-2003).

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    Wilfred G. Rowe describes growing up in a small outport community in the 1920s and 30s, his life as a fisherman’s son and detailing trips to the lumber woods. He relives the events he experienced in the Royal Navy during WWII

    The Design of a Situation-Based Lygon Metainterpreter: I. Simple Changes and Persistence.

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    this report, the author was supported by Project Dynamo, funded by EPSRC. The views expressed in the report are the author's own, and the principal investigators of the project -- John Bell and Wilfred Hodges -- bear no responsibility for them. 5 Two-Sided Resolution 16 6 Implementation 1

    My Old Comrade (2)

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    (Black and White) This card is another version of "My Old Comrade." It appears very similar except that the top question begins by mentioning "has excellent references" and does not provide a price after asking for help. The bottom reads "Please buy a copy" but provides no information to the composer of the song. This card is uninscribed and unposted.This collection previously belonged to Dominic Hibberd, an English biographer most noted for the biographies of Wilfred Owen and Harold Monro, World War I poets. He collected these postcards for research purposes

    For the Empire

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    (Color) This picture looks like an unrolled scroll held down by two small weights and a stem of small white flowers against a red background. The poem, "British Pluck," appears to be written on the paper. The card is unposted but there is a pencil marking of "WWI" on the top left hand corner of the back and some pen writing in the space provided for the stamp that reads "30/12/1914/ Sa: Le:/ (illegible initials)."This collection previously belonged to Dominic Hibberd, an English biographer most noted for the biographies of Wilfred Owen and Harold Monro, World War I poets. He collected these postcards for research purposes

    Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

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    SummaryThe underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DNA repair pathways in laboratory animal models and humans. We demonstrate that dermal fibroblasts from PD patients display flawed nucleotide excision repair (NER) capacity and that Ercc1 mutant mice with mildly compromised NER exhibit typical PD-like pathological alterations, including decreased striatal dopaminergic innervation, increased phospho-synuclein levels, and defects in mitochondrial respiration. Ercc1 mouse mutants are also more sensitive to the prototypical PD toxin MPTP, and their transcriptomic landscape shares important similarities with that of PD patients. Our results demonstrate that specific defects in DNA repair impact the dopaminergic system and are associated with human PD pathology and might therefore constitute an age-related risk factor for PD

    ROTATION--VIBRATION SPECTRUM OF LITHIUM HYDRIDE

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    Author Institution: Department of Chemistry, Harvard University“The rotation-vibration spectrum of LiH has been measured with a small grating spectrometer in the region 1600 to 900cm.1900 cm.^{-1} Three bands, 01,12,230-1, 1-2, 2-3 are prominent. The intensities of lines in these bands will be discussed.

    Low-frequency EPR of ferrimyoglobin fluoride and ferrimyoglobin cyanide: a case study on the applicability of broadband analysis to high-spin hemoproteins and to HALS hemoproteins

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    An EPR spectrometer has been developed that can be tuned to many frequencies in the range of ca 0.1–15 GHz. Applicability has been tested on ferrimyoglobin fluoride (MbF) and ferrimyoglobin cyanide (MbCN). MbF has a high-spin (S = 5/2) spectrum with 19F superhyperfine splitting that is only resolved in X-band along the heme normal. Low-frequency EPR also resolves the splitting in the heme plane. Measurement of linewidth as a function of frequency provides the basis for an analysis of inhomogeneous broadening in terms of g-strain, zero-field distribution, unresolved superhyperfine splittings and dipolar interaction. Rhombicity in the g tensor is found to be absent. MbCN (S = 1/2) has a highly anisotropic low spin (HALS) spectrum for which gx cannot be determined unequivocally in X-band. Low-frequency EPR allows for measurement of the complete spectrum and determination of the g-tensor. Graphical abstract: [Figure not available: see fulltext.]BT/Biocatalysi

    The R. F. A.

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    (Color) This is a poem honoring the Royal Fleet Auxiliary, part of the British Navy. It appears as if written on a scroll under six Allied flags and a the Royal Standard. The stamp is green, British, and cost half-penny. The postcard was postmarked at Chelmsford on November 8, 1915, at 2 P.M. The card was sent from Ernest to his mother.This collection previously belonged to Dominic Hibberd, an English biographer most noted for the biographies of Wilfred Owen and Harold Monro, World War I poets. He collected these postcards for research purposes.TRANSCRIPTION; MESSAGE: C. A. W., Chelmsford; Dear Mother; Just a line to tell you I expect to come home in 5 days leave before leaving England for Inda I expect it will be Inda I don't now will tell you more later Ernest; SENT TO: Mrs. Wilesmith; Uphampton; Ombersley; W Droitwich; Worchestershir

    Somewhere in France

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    (Color) The text of the poem is bordered with dots and roses, with an image of the French and Union Flags at the top. The stamp was removed, and the card is postmarked Sheerness on August 7, 1916, at 9:00 (A.M. or p.m is illegible). The card was sent to "Mam" from "Clever Dom."This collection previously belonged to Dominic Hibberd, an English biographer most noted for the biographies of Wilfred Owen and Harold Monro, World War I poets. He collected these postcards for research purposes.TRANSCRIPTION; MESSAGE: Dear Mam, received letter safe if Den. go to see the boat tell him to come [and] see me. Best love to you. Clever Dom; SENT TO: Miss L. Neal [stamp removal tore off part of the name]; 22 Radnor St; Swindon; Wilts[hire

    INFRARED SPECTRA OF LITHIUM HALIDES

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    1Klemperer and Rice, J. Chem. Phys. 26, 618 (1967), 2^{2}Honig, Mandel, Stitch and Townes, Phys. Rev. 96, 629 (1954). 2^{2}Miller and Kuseh, J. Chem. Phys. 25, 860 (1956).Author Institution: Department of Chemistry, Harvard University“Infrared absorption spectra of LiC1, LiBr, and LiI vapors have been measured with a small grating spectrometer in the region of the fundamental vibration frequency. The absorptions previously reported1 are now definitely assigned to diatomic molecules. Considerably more accurate vibration frequencies together with anharmonic constants have been obtained. These data when combined with microwave measurements2 provide values for the first six derivatives of the potential energy curve. Other weak absorptions have now been observed and are assigned as the infrared active fundamentals of the dimeric molecules.3
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