4,057 research outputs found
"Venture philanthropy in public schools in Australia: tracing policy mobility and policy networks": Conference Presentation by Emma Rowe. (As part of Symposium: "Philanthropy in Australian Public Schooling", with Anna Hogan, Jessica Gerrard, Elisa Di Gregorio and Alexandra Williamson.)
No full text"Venture philanthropy in public schools in Australia: tracing policy mobility and policy networks": Conference Presentation by Emma Rowe. (As part of Symposium: "Philanthropy in Australian Public Schooling", with Anna Hogan, Jessica Gerrard, Elisa Di Gregorio and Alexandra Williamson.
Plasmodium falciparum:Rosettes do not protect merozoites from invasion-inhibitory antibodies
No full textRosetting is a parasite adhesion phenotype associated with severe malaria in African children. Why parasites form rosettes is unknown, although enhanced invasion or immune evasion have been suggested as possible functions. Previous work showed that rosetting does not enhance parasite invasion under standard in vitro conditions. We hypothesised that rosetting might promote invasion in the presence of host invasion-inhibitory antibodies, by allowing merozoites direct entry into the erythrocytes in the rosette and so minimising exposure to plasma antibodies. We therefore investigated whether rosetting influences invasion in the presence of invasion-inhibitory antibodies to MSP-1. We found no difference in invasion rates between isogenic rosetting and non-rosetting lines from two parasite strains, R29 and TM284, in the presence of MSP-1 antibodies (P = 0.62 and P = 0.63, Student's t test, TM284 and R29, respectively). These results do not support the hypothesis that rosettes protect merozoites from inhibitory antibodies during invasion. The biological function of rosetting remains unknown
Author, Philosopher Alexandra Stoddard to Speak March 2 at Williams Library
No full textOXFORD, Miss. – Contemporary philosopher, author, interior designer and speaker Alexandra Stoddard gives an inspirational lecture and reading March 2 at the University of Mississippi
Stages for the More Sustainable Farm
No full textCurrently, agricultural farm units are faced with a double and most times contradictory challenge, in order to be successful: on the one hand the invested capital has to be profitable and the economic performance has to be maximised. On the other hand, given the socio-environmental situation, it is necessary to preserve and to protect the environment and natural resources. Given the potential conflict of the two aims, since the satisfaction of one implies the underperformance of the other (and vice versa), the question then is: which is the solution to choose? We intend, in this work, to formulate a farm plan with the purpose of reconciling the criteria of environmental sustainability with that of economic competitiveness. For this achievement we proceed to the comparative study of sustainability of different groups of farms identified in the study area (first evaluation cycle) through MESMIS (“Marco para la Evaluación de Sistemas de Manejo de Recursos Naturales Mediante Indicadores de Sustentabilidad” - Framework for Evaluation of Natural-Resource Systems Handling through Sustainability Indicators) methodology, that allowed to select the more sustainable group of farms. Based on the found potentialities and weakness on these production systems, we stepped to the planning of a production unit of bovine meat, which obeys simultaneously to economic and environmental objectives, using Multicriteria Decision. We finished the work with the sustainability evaluation between groups of farms identified previously and the planned farms (second evaluation cycle), based, again, in the MESMIS methodology, to confirm (or not) the greatest sustainability of the last ones. Analyses of the results allow us to confirm the greatest relative sustainability of the planned farm, for the diverse traced scenarios.Decision taking, planning, sustainability, Environmental Economics and Policy, Farm Management,
Assessing phenotypes of Thioclava electrotrophica
No full textBy Alexandra Marquardt, Biology
Advisor: Annette Rowe
Presentation ID: PM_D25
Abstract: One of the main challenges of understanding microbial function in environmental systems is the lack of genetic techniques that allow us to assess phenotypes. This has been especially true in chemolithoautotrophs which are often challenging to grow in the lab. To aim this, we have been developing techniques for transferring genetic information into the facultative chemolithoautotroph, Thioclava electrotrophica ElOx9. Having developed a media compatible for growth with both E. coli and T. electrotrophic, we have successfully developed a conjugation protocol that has allowed us to transform T. electrotrophica with both a fluorescent marker and introduce the minMar transposon. In this work we will present the mating efficacy for this process. In order, assess future compatibility with more additional genetic techniques like CRISPR CAS-9 mediated genome editing, we have also been investigating the potential for electroporation, stemming from recent work published for Shewanella. Our current work suggested that Thioclava are capable of withstanding the electroporation conditions, which hold promise for the potential of this approach to yield genetic transformation. Our future work will entail using these techniques to construct a library of gene deletion mutants using transposon mutagenesis that can be used to assess the genes involved in chemolithoautotrophic growth of T. electrotrophica on elementals sulfur and electron uptake from electrodes, to further study the potential genes involved in these processes
Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies
No full textMalaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA). CSA binding infected erythrocytes also bind IgM natural antibodies from normal human serum, a process that may facilitate placental adhesion or promote immune evasion. The parasite ligands that mediate placental adhesion are thought to be members of the variant erythrocyte surface antigen family P. falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by the var genes. Two var gene sub-families, var1CSA and var2CSA, have been identified as parasite CSA binding ligands and are leading candidates for a vaccine to prevent pregnancy-associated malaria. We investigated whether these two var gene subfamilies implicated in CSA binding are also the molecules responsible for IgM natural antibody binding. By heterologous expression of domains in COS-7 cells, we found that both var1CSA and var2CSA PfEMP1 variants bound IgM, and in both cases the binding region was a DBL epsilon domain occurring proximal to the membrane. None of the domains from a control non-IgM-binding parasite (R29) bound IgM when expressed in COS-7 cells. These results show that PfEMP1 is a parasite ligand for non-immune IgM and are the first demonstration of a specific adhesive function for PfEMP1 epsilon type domains
Exhibiting Fashion Symposium: Dr. Alexandra Palmer “Fashion Exhibitions: The Good, the Bad, and the Pointless”
No full textThe Museum at FIT presented Exhibiting Fashion, its twenty-first academic symposium on Friday, March 8, 2019. This symposium explored the history of fashion curating, the different ways fashion is displayed in museum settings, and how national and regional identities influence fashion exhibitions. The symposium was organized in conjunction with Exhibitionism: 50 Years of The Museum at FIT, which commemorated the rich history of the museum, the site of more than 200 exhibitions since the 1970s.Dr. Alexandra Palmer is the Nora E. Vaughan Senior Curator at the Royal Ontario Museum. She has curated numerous exhibitions including Christian Dior, and she is the author of the book Christian Dior: History and Modernity, 1947–1957
Reescrita de si pelo outro: identidade portuguesa e paródia em Deus-dará, de Alexandra Lucas Coelho / Rewriting oneself through the other: Portuguese identity and parody in Deus-dará, by Alexandra Lucas Coelho
No full textResumo: O artigo aponta o modo como o romance Deus-dará de Alexandra Lucas Coelho, escritora portuguesa contemporânea, pode ser compreendido como um exercício de renegociação da identidade portuguesa em relação a questões referentes à colonização no Brasil. Mais do que isso, problematiza-se como, por meio da estratégia da paródia no texto ficcional, a autora consegue expressar uma necessidade e possibilidade de se redefinir pelo outro em um movimento contrário ao do discurso colonial – o que também ocorre em suas entrevistas e em suas narrativas de viagens, tais como em Vai, Brasil e Cinco Voltas na Bahia e um beijo para Caetano Veloso. Palavras-chave: identidade portuguesa; paródia; pós-modernismo; escrita portuguesa contemporânea; Alexandra Lucas Coelho. Abstract: The article observes how the novel Deus-dará, by Alexandra Lucas Coelho, a Portuguese contemporary writer consists in an exercise of renegotiation for the Portuguese identity in relation to issues that refer to the colonization process in Brazil. Moreover, this text seeks to show how parody as a fictional literary strategy helps the author in expressing a necessity and a possibility of redefining oneself through the other, in a direction that goes in the opposite way of the colonial speech. This necessity and this possibility also appear in the author’s interviews and travel books, such as Vai, Brasil and Cinco Voltas na Bahia e um beijo para Caetano Veloso, which will also be mentioned in this article.Keywords: Portuguese identity; parody; post-modernism; Portuguese contemporary writing; Alexandra Lucas Coelho
Author Rights Workshop
No full textLearning material associated with Alexandra Kohn's presentation as a part of the ABC Copyright 2020 Fall Speaker Series, hosted by the University of Alberta Copyright Office
Athaliah and Alexandra: Gender and Queenship in Josephus [Author Accepted Manuscript]
No full textAthaliah and Alexandra were the only two women to rule as queens of Judah/Judaea in their own right and both women’s reigns are reported in Josephus’ writings. Despite their uniqueness, however, Athaliah and Alexandra are rarely compared in scholarship; the former is usually dismissed, and focus centred on the latter. This article contends that there are historical similarities between the two, but literary differences. Josephus could have referred to Athaliah or used elements of her portrayal in his presentation of Alexandra but does not, creating the impression that Alexandra was completely different to her predecessor. It may be instructive, therefore, to consider why Josephus literarily isolates the queens and what this means for his interpretation of Alexandra
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