1,720,972 research outputs found

    Renal involvement in psychological eating disorders

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    Psychological eating disorders--anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder--are an increasing public health problem with severe clinical manifestations: hypothermia, hypotension, electrolyte imbalance, endocrine disorders and kidney failure; they are of interest to nephrologists, but pathophysiological mechanisms in determining the renal involvement are still unclear. We describe pathophysiology, histological features and clinical manifestations of the most frequent psychological eating disorders: AN and BN. Regarding AN, we analyze the recent literature, and identify 3 principal pathways towards renal involvement: chronic dehydration-hypokalemia, nephrocalcinosis and chronic rhabdomyolysis. Regarding BN, we describe the correlation between obesity and many proinflammatory cytokines, chemokines, growth factors and adipokines, having potential metabolic and hemodynamic effects on the kidney and an important role in the pathogenesis of obesity-related renal injury, independently of hypertension and diabetes

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Quality of life in Sicilian Patients on PD. Clinical and psychological changes with age and duration of treatment

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    Objective: In relation to chronological and dialytic age, we have studied for 6 months the quality of life (QoL) of 56 stable subjects on peritoneal dialysis (PD), and also nutritional, immunological, and dialytic efficiency factors, com- pared to psychological tests. Methods: We divided the patients (pts) into 4 age groups: G1 (up to 49 years), G2 (50–59 years), G3 (60–69 years), G4 (over 70 years). Age-based dialysis in months (m) in 3 groups: 1–12 m, 13–36 m, 37– 90 m. Clinical parameters: nutritional, immunological, and dialytic efficiency values: albumin, Hb, WBC, ferritin, C3, C4, BMI, IgG, IgA, IgM, C-reactive pro- tein (CRP), CA125, Ca19-9, GFR, Kt/V, CCL, PTH. Psychometric tests: SF-36, POMS, MHLCS, MPSS, COPE. Results: In all pts during the observations is detected: significant worsening of SF-36 AF (0.04) and SF-36 AS (0.02) and MHLC internal (0.05), that shows the tendency of pts to personally manage their health condition; decrease of GFR (0.00) and CCL Tot (0.00); increase of Ca19-9 (0.01); decrease of Kt/V close to significance (0.07); increase of C3 close to significance (0.07); an increase of BMI close to significance (0.06). Chronological age (yrs): G1 (up to 49): worsening levels of depression and anxiety (POMS) almost significant (0.07). Decrease of GFR values close to significance (0.07). G2 (up to 59): worsening of SF-36 AS (0.07), increased levels of anxiety and tension at the POMS (0.03), of research support-help (COPE; 0.05), of PCR (0.04), C3 (0.00), and IgM (0.04). G3 (60–69): increase of PCR (0.02) and Alb (0.04), no significant increase in BMI. G4 (over 70): no significant changes in studied parameters. Dialytic age (m): 1–12: increase of Ca19-9 (0.05), C3 (0.01), and PTH (0.04); 13–36: worsening of SF-36-AF (0, 05); 37–90: increase of C3 (0.01) and PTH (0.04). Conclusions: Our study suggests that PD pts, especially those of G2 and dialytic age 13–36 months, implement a worse QoL compared to the physical capabilities and the impact of pain (SF-36, POMS). Proinflammatory indices (C3, Ca19-9, PCR, PTH) vary with dialytic age, prob- ably for the current poor biocompatibility of PD. With the support of family and life expectancy, pts over 70 years are the only group without significant changes, confirming that the PD treatment is more convenient at this age

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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