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When a death apparently associated to sexual assault is instead a natural death due to idiopathic hypereosinophilic syndrome: The importance of gamma-hydroxybutyric acid analysis in vitreous humor
Get PDFWe here report a case involving a 21-year-old female, found dead in a central square of a city in the south of
Italy. Initial evidences and circumstances were suggestive of a death associated with a sexual assault. Two
peripheral blood and two vitreous humor samples were collected for the purpose of gamma-hydroxybutyric acid
(GHB) testing from the dead body at two different post-mortem intervals (PMIs): approximately 2 (t0) and 36 (t1)
hours. The obtained results showed that, between t0 and t1, there was an increase of GHB concentrations in
peripheral blood and vitreous humor of 66.3% and 8.1%, respectively.
This case was the first evidence of GHB post mortem production in a dead body and not in vitro, showing that
vitreous humor is less affected than peripheral blood in GHB post-mortem production.
The value detected at t1 in peripheral blood (53.4 μg/mL) exceeded the proposed cut-off and if interpreted
alone would have led to erroneous conclusions. This was not the case of vitreous humor GHB, whose postmortem increase was minimal and it allowed to exclude a GHB exposure.
Only after a broad forensic investigation including a complete autopsy, serological, histological, toxicological
and haematology analyses, a diagnosis of idiopathic hypereosinophilic syndrome, a myeloproliferative disorder
characterized by persistent eosinophilia associated with damage to multiple organs, was made and the cause of
death was due to a pulmonary eosinophilic vasculitis responsible for an acute respiratory failure
L’utilizzo della matrice urinaria in tossicologia forense
No full textThe analysis of conventional (such as blood and urine) and unconventional (such as hair, saliva, sweat) biological matrices allows to detect substances of abuse at different time windows of exposure and provides an important support to forensic toxicology examinations. In this review, the use of the urine matrix in the determination of psychoactive substances and the employed analytical techniques are reported, identifying their advantages and disadvantages, considering also the challenges faced in the investigation on New Psychoactive Substances (NPS). Urine samples are the prevalently used in clinical and forensic toxicology for a number of reasosns: the collection is not invasive, large volumes can be easily obtained, it is possible to analyze exogenous substances and their metabolites after several days of intake. Liquid chromatography and gas chromatography are the most used techniques for screening tests in forensic toxicology since both techniques allow to identify the chemical structure of the analytes under investigation, to distinguish and quantify related substances and their metabolites. In forensic toxicology, the detection of substances of abuse in the urine matrix requires to strictly adhere to definite criteria and steps, from the collection of the sample to its final storage
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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