152 research outputs found
Exploring Persian Lore in the Hebrew Book of Asaf
No full textThe Hebrew medical text referred to as Sefer refu’ot or Sefer Asaf (“Book of Asaf”) has long been considered one of the greatest mysteries of the Hebrew sciences with regards to fundamental questions such as the date and place of its composition and the identity of its author or authors. It has been dated anytime between the third and the eleventh centuries, and its composition has been located anywhere between Persia and southern Italy.
This paper explores some of the Persian lore in Sefer Asaf: the figure of Asaf himself, the similarity with other Persian or Persian-influenced accounts of the origins of the sciences; the appearance of the Indo-Iranian motif of the trees of medicine; the central importance given to Indic medical knowledge and the form and usage of the Persian months as they appear in the text.
Key contributions to the study of Sefer Asaf to date have argued for a Syriac connection while a number of other important studies have linked the text to a Persian cultural milieu. The data I present here links those two together and argues for dependence on material deriving from the Church of the East in Persia
THE ANIMA ARCHTYPE IN ASAF HÂLET ÇELEBİ’S POEMS
No full textEdebî eserde kodlanan kolektif bilinç dışı unsurları belirlemeyi hedefleyen arketipsel
eleştiri, Carl Gustav Jung tarafından şekillendirilmiştir. Yazar ya da şair, ortak/kolektif
bilinç dışında yer alan arketiplere seslendiğinde bireysellikten evrenselliğe
uzanabilmektedir. Cumhuriyet dönemi şairlerinden olan Asaf Hâlet Çelebi; Budizm, Eski
Doğu inançları, tasavvuf ve Türk divan edebiyatı geleneğine göndermelerde bulunarak
mistik bir anlayışla şiirlerini yazar. Masalsı bir atmosfere sahip olan şiirlerinde; bilinç
dışında yaşayan hayallerini, insan ruhunun ortak yanlarıyla kaynaştırarak ifade eder.
Şiirlerinde yer alan bilinç dışı izlerden birisi de, erkekteki dişil yön olarak tanımlanan
“anima” arketipidir. Bu çalışmada, Asaf Hâlet Çelebi’nin şiirlerinde anima arketipinin dışa vurumları araştırılmış ve elde edilen bulgular değerlendirilmiştir. Yapılan çalışma
sonucunda Jung’un, her bireyin ortak/kolektif bilinç dışında yer aldığını vurguladığı
arketiplerden olan anima arketipinin, Asaf Hâlet Çelebi’nin şiirlerinde de etkin bir şekilde
kullanıldığı görülmüştür. Böylece şairin arketiplerden yararlandığı, şiirleri sayesinde bilinç dışındakini bilinç düzeyine çıkarabildiği ve bireysellikten evrenselliğe uzanan köprüyü arketipler ile kurduğu sonucuna ulaşılmıştır.The archetypal critic that aims to detect collective unconscious objects
coded in literal works is formed by Carl Gustav Jung. When author or poet used archetypes
of humanity, he/she may reach to universality from individuality. Asaf Hâlet Çelebi who is
one of Republic period poets, expresses his unconscious dreams by mixing common traces
of human soul in his poems that have epic atmosphere. One of the unconscious traces in his
poems is “anima” archetype that is defined as feminine side of male. In this study,
expressions of anima archetype in Asaf Hâlet Çelebi’s poems are surveyed and outcomes
are evaluated. The performed study have shown that anima archetype which has been
expressed by Jung as a common/collective unconscious archetype in every person is widely
seen in Asaf Hâlet Çelebi’s poems. Therefore, it has been discovered that Poet benefited
from archetypes and outcomed the unconscious things to consciousness level. Once all the
obtained results of this study are evaluated, it is seen that the bridge from single personality
to universality can be formed by using archetypes in literal works
GILA, a Replacement for the Soft‐Agar Assay that Permits High‐Throughput Drug and Genetic Screens for Cellular Transformation
No full textThe International Arbitration of Territorial Disputes
No full textAsaf Siniver provides a systematic and comparative analysis of the role of international arbitration in the settlement of interstate territorial disputes. He engages with International Relations (IR) and International Law (IL) scholarships to locate the unique characteristics of arbitration as a legal method of dispute settlement, distinct from the other legal method of adjudication ('judicial settlement') and diplomatic methods such as negotiation and mediation.A novel framework examines both political and legal dimensions to analyse (i) under what conditions states are more likely to pursue a legal settlement of their territorial dispute via arbitration as opposed to the more popular diplomatic method of mediation, and (ii) what explains compliance with, or defiance of international law in such cases. In so doing, the author sets to reclaim the sui generis nature of arbitration as a unique legal-political method which enables the disputants to maintain the considerable flexibility and autonomy often found in mediation, whilst providing the same final and legally binding solution that adjudication offers.Exploring a wide range of primary sources, including interviews, archival research, and official documents, and employing qualitative research methods, Siniver applies the analytical framework to four contemporary cases of international arbitration: the arbitration over the Rann of Kutch between India and Pakistan (1966-68); the Beagle Channel arbitration between Chile and Argentina (1971-77), the Taba arbitration between Egypt and Israel (1986-88), and the South China Sea arbitration between The Philippines and China (2013-16)
Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity
No full textAbstract
Malignant brain tumours are the cause of a disproportionate level of morbidity and mortality among cancer patients, an unfortunate statistic that has remained constant for decades. Despite considerable advances in the molecular characterization of these tumours, targeting the cancer cells has yet to produce significant advances in treatment. An alternative strategy is to target cells in the glioblastoma microenvironment, such as tumour-associated astrocytes. Astrocytes control multiple processes in health and disease, ranging from maintaining the brain’s metabolic homeostasis, to modulating neuroinflammation. However, their role in glioblastoma pathogenicity is not well understood. Here we report that depletion of reactive astrocytes regresses glioblastoma and prolongs mouse survival. Analysis of the tumour-associated astrocyte translatome revealed astrocytes initiate transcriptional programmes that shape the immune and metabolic compartments in the glioma microenvironment. Specifically, their expression of CCL2 and CSF1 governs the recruitment of tumour-associated macrophages and promotes a pro-tumourigenic macrophage phenotype. Concomitantly, we demonstrate that astrocyte-derived cholesterol is key to glioma cell survival, and that targeting astrocytic cholesterol efflux, via ABCA1, halts tumour progression. In summary, astrocytes control glioblastoma pathogenicity by reprogramming the immunological properties of the tumour microenvironment and supporting the non-oncogenic metabolic dependency of glioblastoma on cholesterol. These findings suggest that targeting astrocyte immunometabolic signalling may be useful in treating this uniformly lethal brain tumour.</jats:p
Qadi an-Nu'man The Fatimid Jurist and Author
No full textAny complete biography of Qādī an-Nu'mān, the most illustrious of Ismā'īlī jurists, must necessarily be based on two kinds of sources, internal and external. He was a very prolific author, and although not all his works which were extant some 400 years ago have come down to us, a good many of his akhbār and fiqh works are still preserved. It would be necessary to go through all of these and collect all autobiographical information before the definitive biography of the Qāḍī can be attempted. Even purely fiqh works like the Mukhtaṣaru'l-Athār contain occasional references to contemporary events. The brief biography given below does not profess to be exhaustive; it is based in the main on three external sources, which seem to contain all that was definitely known of this great lawyer, the founder and the greatest exponent of Ismā'īlī jurisprudence. The difficulty of writing on Ismā'īlī subjects is well known; it is next to impossible to expect any co-operation from the sectarians themselves. I am trying, however, to obtain information from different sources, and if ever I am able to study all the works extant of the Qāḍī, a more comprehensive biography may be attempted.</jats:p
Cluster and alpha decay of superheavy nuclei
No full textWe investigated cluster radioactivity and alpha decay of some superheavy nuclei with atomic numbers Z = 119, 120 , which may be produced in the future. Two models are used to calculate the half-lives against cluster radioactivity: ASAF (Analytical Super-Asymmetric Fission) and UNIV (Universal Formula). For decay half-lives we are based on four models: ASAF, UNIV, semFIS (semi-empirical formula based on Fission Theory) and AKRA (first author Akrawy). The Q -values are calculated using the theoretical model of atomic masses WS10, which sometimes is called W4
Sintering time dependence of iron diffusion in MgB2 and its effect on superconducting properties
No full textWe have investigated the effects of the iron diffusion on the crystal structure and superconducting properties of pelletised magnesium dihoride (MgB2) bulk samples employing X-ray diffraction (XRD), critical transition temperature, and room temperature resistivity measurements. The Fe diffusion into MgB2 bulk pellets upon sintering at 900 degrees C has been studied for sintering time durations of 15 minutes, 30 minutes, 1 hour, 2 hours, and 4 hours. We have carried out XRD and room temperature resistivity determinations along the depth starting from iron coated surface by successive removal of thin layers from the surface mechanically. Sintering time dependence of the Fe diffusion coefficients has been calculated from depth profiles of lattice parameter c and room temperature resistivity values. It has been found that the Fe diffusion coefficient decreases with increasing sintering time
Abstract 600: Melanoma and ovarian cancer cells tested for drug sensitivity using anchorage-independent growth
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