102,146 research outputs found
Prima caratterizzazione morfologica e chimica di semi e baccelli di una varietà locale di vigna
No full textLe leguminose da granella hanno rappresentato tradizionalmente una importante fonte alimentare diffusa tra tutte
le popolazioni italiane che hanno provveduto nel corso del tempo a selezionare quelle più idonee ai diversi ambienti di
coltivazione. La conclusione recente dei progetti Agrigenet e Salve, finanziati dal PSR Regione Campania 2007-2013,
ha messo in evidenza un abbondante patrimonio di varietà tradizionali particolarmente di fagiolo, cece e cicerchia. Tra i
legumi meno noti e poco diffusi in coltivazione vi sono le vigne. La Vigna unguiculata (L.) Walp.è una specie che era
presente nelle coltivazioni del territorio campano, seppure in misura molto ridotta rispetto al fagiolo. Nell’ambito delle
attività di salvaguardia della agrobiodiversità e di rivalutazione dei legumi come alimenti funzionali è stato avviato lo
studio su una varietà locale di Vigna unguiculata reperita presso un agricoltore (Angela Capuano) che ne tramanda la
coltivazione così come veniva fatta dalla bisnonna dalla prima metà del secolo scorso nel territorio di Castel San
Giorgio (SA), caratterizzato da suoli prevalentemente limoso-sabbiosi, di buona fertilità
Alignment-Free Sequence Comparison over Hadoop for Computational Biology
No full textSequence comparison i.e., The assessment of how similar two biological sequences are to each other, is a fundamental and routine task in Computational Biology and Bioinformatics. Classically, alignment methods are the de facto standard for such an assessment. In fact, considerable research efforts for the development of efficient algorithms, both on classic and parallel architectures, has been carried out in the past 50 years. Due to the growing amount of sequence data being produced, a new class of methods has emerged: Alignment-free methods. Research in this ares has become very intense in the past few years, stimulated by the advent of Next Generation Sequencing technologies, since those new methods are very appealing in terms of computational resources needed and biological relevance. Despite such an effort and in contrast with sequence alignment methods, no systematic investigation of how to take advantage of distributed architectures to speed up alignment-free methods, has taken place. We provide a contribution of that kind, by evaluating the possibility of using the Hadoop distributed framework to speed up the running times of these methods, compared to their original sequential formulatio
Neoliberalism’s public-sector impact: the US and Germany compared
No full textSauer C, Valet P, Roscigno VJ, Wilson G. Neoliberalism’s public-sector impact: the US and Germany compared. In: Warhurst C, Mathieu C, Dwyer RE, eds. The Oxford Handbook of Job Quality. Oxford: Oxford University Press; 2022: 469-485
Phytomorphological and Essential-Oil Characterization in situ and ex situ of Wild Biotypes of Oregano Collected in the Campania Region (Southern Italy)
No full textOregano is an aromatic species of great interest which spreads spontaneously in the Mediterranean area but its genetic resources are not yet adequately developed. Moreover the results of studies of wild strains of different origin - although quite numerous - are not always comparable, and therefore the effects of environment and genotype cannot be distinguished. The identify of three wild, white-flowered biotypes of oregano collected in the Campania Region (Southern Italy) and the assessment of the effects of genotype and environment through the comparison in situ and ex situ were studied. The determination allowed to identify the biotypes belonging to two different subspecies: Origanum vulgare ssp. virens and Origanum vulgare ssp. viridulum. The percentage of oil yield was higher for the biotype belonging to ssp. virens and it was significantly correlated with the glandular and stomatal density. The chemical characterization of the oils obtained by hydrodistillation was found to be influenced by the genotype and conditions of plant growth
Complex Formation between Poly(vinylpyrrolidone) and Sodium Decyl Sulfate Studied through NMR
No full textRecent experimental studies have shown a preferential interaction of poly(vinylpyrrolidone) (PVP) toward the alkyl sulfate surfactants rather than toward those belonging to the alkyl sulfonate series. To gain information on the complex formation between PVP and the alkyl sulfate surfactants, we have performed H-1 and C-13 NMR and NOESY measurements on aqueous solutions of sodium decyl sulfate (C10OS) in the presence and absence of PVP at 1wt %. The results show that C10OS interacts with PVP, forming micelle-like clusters bound onto the polymer, and furthermore suggest that the PVP-C10OS complex formation implies the synergic effects of the electrostatic attractions between the surfactant headgroup and the nitrogen and oxygen atoms in the pyrrolidone ring of PVP and of the hydrophobic interaction between the surfactant alkyl moiety and the ring carbons of PVP
Ultrasmall Carbon Nanodots as Theranostic Nanoheaters for Precision Breast Cancer Phototherapy: Establishing the Translational Potential in Tumor-in-a-Dish Models
No full text: This study investigates the remarkable attributes of sulfur-doped carbon nanodots (CDs) synthesized in high yield and a narrow size distribution (4.8 nm). These CDs exhibit notable features, including potential bioelimination through renal clearance and efficient photothermal conversion in the near-infrared region with multicolor photoluminescence across the visible spectrum. Our research demonstrates high biocompatibility and effective near-infrared (NIR)-triggered photothermal toxicity when targeting mammospheres and patient-derived tumor organoids. Moreover, the study delves into the intricate cellular responses induced by CD-mediated hyperthermia. This involves efficient tumor mass death, activation of the p38-mitogen-activated protein kinase (MAPK) pathway, and upregulation of genes associated with apoptosis, hypoxia, and autophagy. The interaction of CDs with mammospheres reveals their ability to penetrate the complex microenvironment, impeded at 4 °C, indicating an energy-dependent endocytosis mechanism. This observation underscores the CDs' potential for targeted drug delivery, particularly in anticancer therapeutics. This investigation contributes to understanding the multifunctional properties of sulfur-doped CDs and highlights their promising applications in cancer therapeutics. Utilizing 3-D tumor-in-a-dish patients' organoids enhances translational potential, providing a clinically relevant platform for assessing therapeutic efficacy in a context mirroring the physiological conditions of cancerous tissues
Reversal of chloroquine resistance of wild isolates of Plasmodium falciparum by desipramine
No full textComplex formation between poly(vinylpyrrolidone) and sodium decyl sulfate studied through NMR
No full text- …
